Patents by Inventor Srishtee Arora

Srishtee Arora has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and use of a fibrinogen binding motif present in EFB and COA for therapeutics and vaccines against
    Patent number: 11407819
    Abstract: The present disclosure provides methods and composition including vaccines, monoclonal antibodies, polyclonal antibodies, chimeric molecule of an extracellular fibrinogen binding protein (Efb) and targeted agent delivery pharmaceutical composition comprising at least a portion of a modified N-terminus region, at least a portion of a modified C-terminus region, or both, wherein the modified extracellular fibrinogen binding protein results in inhibiting the fibrinogen binding, C3 binding, or both or administering to a subject a pharmacologically effective amount of a vaccine in a pharmaceutically acceptable excipient, comprising a modified extracellular fibrinogen binding protein comprising at least a portion of a modified N-terminus region, at least a portion of a modified C-terminus region, or both, wherein the modified extracellular fibrinogen binding protein results in not shielding the staphylococcus bacterium from recognition by a phagocytic receptor.
    Type: Grant
    Filed: May 20, 2020
    Date of Patent: August 9, 2022
    Assignees: The Texas A&M University System, Technische Universität Braunschweig, Università Degli Studi Di Pavia
    Inventors: Ya-Ping Ko, Magnus Hook, Srishtee Arora, Livia Visai, Federico Bertoglio, Michael Hust, Doris Meier