Patents by Inventor Srividya Akella

Srividya Akella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Autonomous replication sequences and episomal DNA molecules
    Patent number: 9447422
    Abstract: The present invention provides autonomous replication sequences (ARSs) isolated from Nannochloropsis that support the replication of episomal DNA molecules (EDMs) in eukaryotic cells. The ARSs and EDMs provided herein can be used for expressing genes in organisms including algae and heterokonts.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: September 20, 2016
    Assignee: Synthetic Genomics, Inc.
    Inventors: Peter DeHoff, Leah Soriaga, Srividya Akella
  • Cell systems and methods for improving fatty acid synthesis by expression of dehydrogenases
    Patent number: 9181568
    Abstract: The invention relates to methods for producing lipids such as fatty acid products in recombinant host cells engineered to express a non-native gene encoding a dehydrogenase. The recombinant microorganisms are able to proliferate at a higher rate as compared with microorganisms that do not express a non-native dehydrogenase gene, and cultures of microorganisms that are engineered for lipid production and that express a non-native dehydrogenase produce more lipid than cultures of control microorganisms that do not include a non-native dehydrogenase gene.
    Type: Grant
    Filed: April 23, 2012
    Date of Patent: November 10, 2015
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: Robert Christopher Brown, Jennifer Coppersmith, Prachee Prakash, Srividya Akella, Rekha Seshadri
  • AUTONOMOUS REPLICATION SEQUENCES AND EPISOMAL DNA MOLECULES
    Publication number: 20150094209
    Abstract: The present invention provides autonomous replication sequences (ARSs) isolated from Nannochloropsis that support the replication of episomal DNA molecules (EDMs) in eukaryotic cells. The ARSs and EDMs provided herein can be used for expressing genes in organisms including algae and heterokonts.
    Type: Application
    Filed: December 6, 2013
    Publication date: April 2, 2015
    Applicant: Synthetic Genomics, Inc.
    Inventors: Peter DeHoff, Leah Soriaga, Srividya Akella
  • Regulation of toxin and antitoxin genes for biological containment
    Patent number: 8975061
    Abstract: The present invention relates to the regulation of a toxin and/or antitoxin genes in a genetically engineered microorganism, such as cyanobacterial or eukaryotic algal strains, in particular for preventing unintentional and/or uncontrolled spread of the microorganisms.
    Type: Grant
    Filed: June 28, 2012
    Date of Patent: March 10, 2015
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: Vincent A. Bielinski, Nicholas Bauman, Kate Lyons Boyd, Srividya Akella, Stanley Bower, Paul G. Roessler
  • CELL SYSTEMS AND METHODS FOR IMPROVING FATTY ACID SYNTHESIS BY EXPRESSION OF DEHYDROGENASES
    Publication number: 20130280793
    Abstract: The invention relates to methods for producing lipids such as fatty acid products in recombinant host cells engineered to express a non-native gene encoding a dehydrogenase. The recombinant microorganisms are able to proliferate at a higher rate as compared with microorganisms that do not express a non-native dehydrogenase gene, and cultures of microorganisms that are engineered for lipid production and that express a non-native dehydrogenase produce more lipid than cultures of control microorganisms that do not include a non-native dehydrogenase gene.
    Type: Application
    Filed: April 23, 2012
    Publication date: October 24, 2013
    Applicant: ExxonMobil Research and Engineering Company
    Inventors: Robert Christopher Brown, Jennifer Coppersmith, Prachee Prakash, Srividya Akella, Rekha Seshadri
  • REGULATION OF TOXIN AND ANTITOXIN GENES FOR BIOLOGICAL CONTAINMENT
    Publication number: 20130023035
    Abstract: The present invention relates to the regulation of a toxin and/or antitoxin genes in a genetically engineered microorganism, such as cyanobacterial or eukaryotic algal strains, in particular for preventing unintentional and/or uncontrolled spread of the microorganisms.
    Type: Application
    Filed: June 28, 2012
    Publication date: January 24, 2013
    Applicant: ExxonMobil Research and Engineering Company
    Inventors: Vincent A. Bielinski, Nicholas Bauman, Kate Lyons Boyd, Srividya Akella, Stanley Bower, Paul G. Roessler