Patents by Inventor Stéphane DESGRANGES

Stéphane DESGRANGES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230404920
    Abstract: The present invention relates to calibrated (per)fluorocarbon nanodroplets comprising an outer layer and an inner core, said outer layer comprising a biocompatible fluorinated surfactant and said inner core comprising a (per)fluorocarbon. The invention further relates to a method of preparation of said calibrated (per)fluorocarbon nanodroplets through microfluidic technique, and to their use for in vivo or in vitro diagnostic and/or for therapy.
    Type: Application
    Filed: November 11, 2021
    Publication date: December 21, 2023
    Inventors: Romain MELICH, Philippe BUSSAT, Samir CHERKAOUI, Christiane CONTINO-PEPIN, Stéphane DESGRANGES
  • Publication number: 20230191383
    Abstract: A dry formulation obtained by desiccation of an emulsion comprises at least one surfactant, at least one lipophilic compound, and at least one metal catalyst. The dry formulation may be used to carry out a catalysed reaction in an aqueous medium. The dry formulation has a water content of less than (10) wt% relative to the total weight of the dry formulation, and wherein: - the at least one surfactant is selected from the group comprising dendrimers of Dendri-TAC type, oligomers of F,TACn or H,TACn type, TPGS 1000, TPGS 750 M, surfactants derived from sugars and/or amino acids, and combinations thereof; - the at least one lipophilic compound is selected from the group comprising lipids, hydrophobic complexing agents and combinations thereof; and - the metal catalyst comprises a metal selected from Groups (3) to (12) of the Periodic Table.
    Type: Application
    Filed: May 27, 2021
    Publication date: June 22, 2023
    Inventors: Frédéric Bihel, Damien Bourgeois, Christiane Contino-Pepin, Stéphane Desgranges, Valentin Lacanau
  • Publication number: 20220008340
    Abstract: The present description relates to a method for extracting at least one substance of interest, the method comprising the following steps: —providing an admixture comprising water, a source comprising the at least one substance of interest or at least one precursor thereof, at least one surfactant and at least one lipophilic compound; —the emulsification of the admixture, leading to the formation of an emulsion; wherein the emulsion comprises: —a continuous aqueous phase; and a discontinuous lipidic phase comprising the at least one lipophilic compound, the at least one surfactant and at least one substance of interest extracted from the source during the emulsification; wherein the method further comprises the addition of at least one cryoprotectant to the admixture and the lyophilisation of the emulsion.
    Type: Application
    Filed: November 27, 2019
    Publication date: January 13, 2022
    Applicants: AVIGNON UNIVERSITE, LYOFAL, Centre National de la Recherche Scientifique, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER, UNIVERSITE DE MONTPELLIER
    Inventors: Christiane Contino-Pepin, Stéphane Desgranges, Alice Dall`armellina, Charles Duval, Mathias Letan-Martin
  • Publication number: 20210252172
    Abstract: The present description relates to an emulsion comprising an amphiphilic compound, a first phase comprising droplets including at least one perfluorocarbon compound and a second phase, which is aqueous. The droplets have a diameter d4,3 of between 0.5 pm and 5.5 pm, and the at least one perfluorocarbon compound has a boiling point above 100° C. The present description also relates to such an emulsion for use as an improving agent in ultrasound ablation surgery (FIG. 3).
    Type: Application
    Filed: June 14, 2019
    Publication date: August 19, 2021
    Applicants: AVIGNON UNIVERSITE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS, INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE, SORBONNE UNIVERSITE, UNIVERSITE DE MONTPELLIER, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER
    Inventors: Christiane Contino-Pepin, Stéphane Desgranges, Nicolas Taulier
  • Patent number: 10752976
    Abstract: The present invention is in the field of surfactants to extract a platinum group metal or gold, in particular palladium, from organic compositions. In particular, the invention concerns the use of surfactants to back-extract a platinum group metal or gold, in particular palladium, from organic compositions further comprising an extractant of said platinum group metal or gold, in particular palladium from an aqueous solution.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: August 25, 2020
    Assignees: Universite de Strasbourg, Centre National de la Recherche Scientifique, Avignon Universite, Comissariat a l'Energie Atomique et aux Energies Alternatives
    Inventors: Frédéric Jean-Jacques Bihel, Damien Bourgeois, Stéphane Desgranges, Daniel Meyer, Christiane Contino-Pepin, Martine Schmitt, Patrick Hervé Denis Wagner
  • Publication number: 20190316223
    Abstract: The present invention is in the field of surfactants to extract a platinum group metal or gold, in particular palladium, from organic compositions. In particular, the invention concerns the use of surfactants to back-extract a platinum group metal or gold, in particular palladium, from organic compositions further comprising an extractant of said platinum group metal or gold, in particular palladium from an aqueous solution.
    Type: Application
    Filed: May 19, 2017
    Publication date: October 17, 2019
    Applicants: Centre National de la Recherche Scientifique, Universite d'Avignon et des Pays de Vaucluse, Universite de Strasbourg, Commissariat a l'Energie Atomique et aux Energies Alternatives, Ecole Nationale Superieure de Chimie de Montpellier, Universite de Montpellier
    Inventors: Frédéric Jean-Jacques Bihel, Damien Bourgeois, Stéphane Desgranges, Daniel Meyer, Christiane Contino-Pepin, Martine Schmitt, Patrick Hervé Denis Wagner
  • Patent number: 10286091
    Abstract: The present invention relates to novel amphiphilic dendrimers, hereafter denoted Dendri-TAC. The present invention also relates to perfluorocarbon nanoemulsions stabilized by these amphiphilic dendrimers and their uses for in vivo diagnostic and/or for therapy, notably as theranostic tools, for detection and/or treatment of cancer.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: May 14, 2019
    Assignees: UNIVERSITE D'AVIGNON ET DES PAYS DU VAUCLUSE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Stéphane Desgranges, Wlodzimierz Urbach, Lucie Somaglino, Nicolas Taulier, Christiane Pepin
  • Publication number: 20180126011
    Abstract: The present invention relates to novel amphiphilic dendrimers, hereafter denoted Dendri-TAC. The present invention also relates to perfluorocarbon nanoemulsions stabilized by these amphiphilic dendrimers and their uses for in vivo diagnostic and/or for therapy, notably as theranostic tools, for detection and/or treatment of cancer.
    Type: Application
    Filed: May 19, 2016
    Publication date: May 10, 2018
    Inventors: Stéphane DESGRANGES, Wlodzimierz URBACH, Lucie SOMAGLINO, Nicolas TAULIER, Christiane PEPIN