Abstract: Provided are methods for eliminating hematologic cancer stem cells in vivo, and thus preventing cancer relapse. The methods comprise a Signal Transducer and Activator of Transcription 5 (STAT5) antagonist (e.g., a PPAR? agonist) after the patient has had ana initial course of treatment with an anti-cancer agent (e.g., a TKI), to eliminate residual cancer stem cells which cause relapse.

Abstract: Provided are methods for eliminating hematologic cancer stem cells in vivo, and thus preventing cancer relapse. The methods comprise a Signal Transducer and Activator of Transcription 5 (STAT5) antagonist (e.g., a PPARy agonist) after the patient has had ana initial course of treatment with an anti-cancer agent (e.g., a TKI), to eliminate residual cancer stem cells which cause re lapse.

Abstract: The invention concerns a protein present at the surface of hematopoietic stem cells of the lymphoid cell line and mature NK cells, the corresponding isolated cDNA sequence and their uses as marker of said cells and for preparing antibodies directed against said protein. The invention also concerns the uses of said antibodies for selecting cells expressing at their surface said protein.

Abstract: The invention concerns an interconnect device in particular for connection and/or line terminals arranged on-line, comprising first and second interconnect combs facing each other and comprising each a connecting bar, and teeth, extending substantially perpendicularly from the connecting bar, the device comprising elastic teeth and rigid teeth. The teeth of each of the first and second combs are alternately rigid and elastic. The elastic teeth and the rigid teeth of the first comb are located respectively opposite the rigid teeth and the elastic teeth of the second comb.

Abstract: This spring allows an electrical connection to a stripped wire to be made in a terminal strip. It has bearing branch intended to bear against a conducting fixed part and a rear branch, facing the bearing branch, linked via a springy linking region to the latter and the free end of which is curved toward the bearing branch in order to form a moveable pinching branch having, on the same side as its free end, an appreciably plane part provided with an opening intended for passage of the conducting fixed part and of the stripped wire in such a way that the edge of the opening lying on the same side as the free end of the moveable pinching branch keeps the stripped end of the wire pressed against the conducting fixed part. A linking region springingly links the two branches. On the opposite side from the rear branch, the bearing branch is provided with a guiding region which extends parallel to the pinching branch.

Abstract: This device is made from a flat resilient material, which has a first branch intended to bear against a fixed conducting part of a connection terminal, a moving sharply-angled second branch having, on the side of its free end, an approximately planar part provided with an opening intended for passage of the end of a cable to be connected and a part facing the first branch, as well as a linking region which joins the two branches, thus forming a loop. Each branch has a part which is concave toward the outside of the loop and the two concave parts are approximately facing each other and form a narrows inside the loop.