Patents by Inventor Stéphanie Gabrielle DARBRE ABDELRAHMAN

Stéphanie Gabrielle DARBRE ABDELRAHMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210145950
    Abstract: The present application relates to arenaviruses with rearrangements of their open reading frames (“ORF”) in their genomes. In particular, described herein is a modified arenavirus genomic segment, wherein the arenavirus genomic segment is engineered to carry a viral ORF in a position other than the wild-type position of the ORF. Also described herein are trisegmented arenavirus particles comprising one L segment and two S segments or two L segments and one S segment. The arenavirus, described herein may be suitable for vaccines and/or treatment of diseases and/or for the use in immunotherapies.
    Type: Application
    Filed: July 7, 2020
    Publication date: May 20, 2021
    Inventors: Daniel David Pinschewer, Doron Merkler, Sandra Margarete Kallert, Mario Kreutzfeldt, Stéphanie Gabrielle Darbre Abdelrahman, Nicolas Jean Page
  • Patent number: 10722564
    Abstract: The present application relates to arenaviruses with rearrangements of their open reading frames (“ORF”) in their genomes. In particular, described herein is a modified arenavirus genomic segment, wherein the arenavirus genomic segment is engineered to carry a viral ORF in a position other than the wild-type position of the ORF. Also described herein are trisegmented arenavirus particles comprising one L segment and two S segments or two L segments and one S segment. The arenavirus, described herein may be suitable for vaccines and/or treatment of diseases and/or for the use in immunotherapies.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: July 28, 2020
    Assignee: UNIVERSITÉ DE GENÉVE
    Inventors: Daniel David Pinschewer, Doron Merkler, Sandra Margarete Kallert, Mario Kreutzfeldt, Stéphanie Gabrielle Darbre Abdelrahman, Nicolas Jean Page
  • Publication number: 20170319673
    Abstract: The present application relates to arenaviruses with rearrangements of their open reading frames (“ORF”) in their genomes. In particular, described herein is a modified arenavirus genomic segment, wherein the arenavirus genomic segment is engineered to carry a viral ORF in a position other than the wild-type position of the ORF. Also described herein are trisegmented arenavirus particles comprising one L segment and two S segments or two L segments and one S segment. The arenavirus, described herein may be suitable for vaccines and/or treatment of diseases and/or for the use in immunotherapies.
    Type: Application
    Filed: November 12, 2015
    Publication date: November 9, 2017
    Inventors: Daniel David Pinschewer, Doron Merkler, Sandra Margarete Kallert, Mario Kreutzfeldt, Stéphanie Gabrielle Darbre Abdelrahman, Nicolas Jean Page
  • Patent number: 9809801
    Abstract: Provided herein are genetically modified arenaviruses suitable as vaccines against mycobacterial infections. The invention also relates to pharmaceutical compositions and methods for the prevention and treatment of mycobacterial infections. Specifically, provided herein are pharmaceutical compositions, vaccines, and methods of preventing and treating infections in Mycobacterium tuberculosis.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: November 7, 2017
    Assignee: Université de Genève
    Inventors: Elodie Anne Françoise Belnoue, Stéphanie Gabrielle Darbre Abdelrahman, Arun Thomas Kamath, Paul Lambert, Claire-Anne Siegrist-Julliard, Daniel David Pinschewer
  • Publication number: 20160024476
    Abstract: Provided herein are genetically modified arenaviruses suitable as vaccines against mycobacterial infections. The invention also relates to pharmaceutical compositions and methods for the prevention and treatment of mycobacterial infections. Specifically, provided herein are pharmaceutical compositions, vaccines, and methods of preventing and treating infections in Mycobacterium tuberculosis.
    Type: Application
    Filed: March 14, 2014
    Publication date: January 28, 2016
    Inventors: Elodie Anne Françoise BELNOUE, Stéphanie Gabrielle DARBRE ABDELRAHMAN, Arun Thomas KAMATH, Paul LAMBERT, Claire-Anne SIEGRIST-JULLIARD, Daniel David PINSCHEWER