Patents by Inventor Stacey L. Hembruff

Stacey L. Hembruff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of isogenic drug-resistant cell lines to determine the sequence of chemotherapeutic drug treatment
    Patent number: 7588903
    Abstract: The present invention provides a method for determining a sequence to administer multiple types of chemotherapeutic drugs for killing cancerous cells to reduce the induction of drug cross-resistance in a patient. The methods also involves screening drug candidates to select a lead anticancer drug from amongst a plurality of candidate drugs, the lead having a reduced capacity to induce cross resistance in a patient against one or more known anticancer drugs, and all of the drugs having the ability to kill cancerous cells of the same selected tumour type. Moreover, the methods involve determining a sequence to administer multiple types of cytotoxic drugs for killing undesired cells to reduce the induction of drug cross-resistance in the cells.
    Type: Grant
    Filed: November 26, 2004
    Date of Patent: September 15, 2009
    Inventors: Amadeo Parissenti, Baoqing Guo, David J. Villeneuve, Stacey L. Hembruff