Patents by Inventor Stacey Ruiz

Stacey Ruiz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATMENT OF RHEUMATOID ARTHRITIS AND ACCELERATED ATHEROSCLEROSIS
    Publication number: 20240131153
    Abstract: Compositions and methods for treating rheumatoid arthritis and/or accelerated atherosclerosis are provided, including an inhibitor of oxidized or malondialdehyde-modified low density lipoprotein (LDL) for administration to a subject. Exemplary inhibitors of oxidized LDL include an anti-oxidized LDL antibody, which results in a reduction in the secretion of pro-inflammatory cytokine from primary monocyte in vitro and the plasma cytokine level of inflammatory cytokine in vivo.
    Type: Application
    Filed: May 21, 2023
    Publication date: April 25, 2024
    Inventors: Bertrand C. LIANG, Stacey RUIZ, Christopher John FARINA
  • Methods for treatment of rheumatoid arthritis and accelerated atherosclerosis with an anti-Apo B100 antibody
    Patent number: 11690912
    Abstract: Compositions and methods for treating rheumatoid arthritis and/or accelerated atherosclerosis are provided, including an inhibitor of oxidized or malondialdehyde-modified low density lipoprotein (LDL) for administration to a subject. Exemplary inhibitors of oxidized LDL include an anti-oxidized LDL antibody, which results in a reduction in the secretion of pro-inflammatory cytokine from primary monocyte in vitro and the plasma cytokine level of inflammatory cytokine in vivo.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: July 4, 2023
    Assignee: Abcentra, LLC
    Inventors: Bertrand C. Liang, Stacey Ruiz, Christopher John Farina
  • METAL PROTOPORPHYRIN FOR TREATMENT OF BK VIRUS
    Publication number: 20230023467
    Abstract: The inactivation of BK virus in patients diagnosed with BK virus, those receiving a kidney that is infected or suspected of being infected by BK virus, or in the transplanted kidney before, during, and/or after transplant surgery is described.
    Type: Application
    Filed: July 8, 2022
    Publication date: January 26, 2023
    Inventors: Donald Jeffrey Keyser, Alvaro F. Guillem, Bhupinder Singh, Stacey Ruiz
  • METHODS AND COMPOSITIONS FOR TREATING CANCER
    Publication number: 20220403013
    Abstract: The present invention provides compositions and methods for treating cancer in a subject by administering to the subject an antibody or fragment thereof that binds to oxidized LDL. In some embodiments, the compositions and methods may reduce the size of the tumor, reduce macrophage infiltration, and/or inhibit metastasis.
    Type: Application
    Filed: November 12, 2020
    Publication date: December 22, 2022
    Inventors: Bertrand C. LIANG, Stacey RUIZ, Christopher John FARINA
  • METHOD FOR TREATMENT OF CORONAVIRUS INFECTION
    Publication number: 20210338708
    Abstract: The present invention involves a novel method for treatment of coronavirus infection, including SARS-COV-2. The method comprises administering stannous protoporphyrin and/or cyanocobalamin to a human patient at risk for developing complications from coronavirus infection. The method is particularly useful where a patient has been diagnosed with coronavirus infection or has been exposed to coronavirus but has not developed symptoms of coronavirus infection.
    Type: Application
    Filed: March 18, 2021
    Publication date: November 4, 2021
    Inventors: Donald Jeffrey KEYSER, Alvaro F. GUILLEM, Bhupinder SINGH, Richard A. ZAGER, Stacey RUIZ
  • COMPOSITIONS AND METHODS FOR TREATMENT OF RHEUMATOID ARTHRITIS AND ACCELERATED ATHEROSCLEROSIS
    Publication number: 20210214426
    Abstract: Compositions and methods for treating rheumatoid arthritis and/or accelerated atherosclerosis are provided, including an inhibitor of oxidized or malondialdehyde-modified low density lipoprotein (LDL) for administration to a subject. Exemplary inhibitors of oxidized LDL include an anti-oxidized LDL antibody, which results in a reduction in the secretion of pro-inflammatory cytokine from primary monocyte in vitro and the plasma cytokine level of inflammatory cytokine in vivo.
    Type: Application
    Filed: May 29, 2019
    Publication date: July 15, 2021
    Inventors: Bertrand C. LIANG, Stacey RUIZ, Christopher John FARINA
  • COMPOSITIONS AND METHODS FOR TREATMENT OF PSORIASIS
    Publication number: 20210205448
    Abstract: Compositions and methods for treating a subject with psoriasis are provided, including an inhibitor of oxidized low density lipoprotein (LDL), malondialdehyde-modified epitope in LDL or native LDL for administration. Exemplary inhibitors of oxidized or malondialdehyde-modified LDL include orticumab, a variant antibody or peptides capable of binding oxidized or malondialdehyde-modified LDL, which results in improvement in conditions of psoriasis even in patients that are refractory to ultraviolet A/B therapy and topical steroids.
    Type: Application
    Filed: May 29, 2019
    Publication date: July 8, 2021
    Inventors: Bertrand C. LIANG, Stacey RUIZ, Christopher John FARINA
  • Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody
    Patent number: 10858422
    Abstract: Described herein are peptides and antibodies for prevention and/or therapeutic treatment of mammals, including humans, against systemic lupus erythematosus, as well as diagnosing the presence or absence of antibodies related to increased or decreased risk of developing SLE and/or to disease grading, staging, and/or prognosis.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: December 8, 2020
    Assignee: Abcentra, LLC
    Inventors: Jan Nilsson, Ryan Benjamin Abbott, Bertrand C. Liang, Christopher John Farina, Stacey Ruiz
  • METHODS FOR DIAGNOSING AND TREATING SYSTEMIC LUPUS ERYTHEMATOSUS WITH AN ANTI-APOLIPOPROTEIN B ANTIBODY
    Publication number: 20190284268
    Abstract: Described herein are peptides and antibodies for prevention and/or therapeutic treatment of mammals, including humans, against systemic lupus erythematosus, as well as diagnosing the presence or absence of antibodies related to increased or decreased risk of developing SLE and/or to disease grading, staging, and/or prognosis.
    Type: Application
    Filed: May 31, 2019
    Publication date: September 19, 2019
    Applicant: Abcentra, LLC
    Inventors: Jan Nilsson, Ryan Benjamin Abbott, Bertrand C. Liang, Christopher John Farina, Stacey Ruiz
  • METHODS FOR DIAGNOSING AND TREATING SYSTEMIC LUPUS ERYTHEMATOSUS
    Publication number: 20180318387
    Abstract: Described herein are peptides and antibodies for prevention and/or therapeutic treatment of mammals, including humans, against systemic lupus erythematosus, as well as diagnosing the presence or absence of antibodies related to increased or decreased risk of developing SLE and/or to disease grading, staging, and/or prognosis.
    Type: Application
    Filed: June 15, 2018
    Publication date: November 8, 2018
    Applicant: CardioVax, LLC
    Inventors: Christopher John Farina, Bertrand C. Liang, Stacey Ruiz
  • METHODS FOR DIAGNOSING AND TREATING SYSTEMIC LUPUS ERYTHEMATOSUS
    Publication number: 20170340702
    Abstract: Described herein are peptides and antibodies for prevention and/or therapeutic treatment of mammals, including humans, against systemic lupus erythematosus, as well as diagnosing the presence or absence of antibodies related to increased or decreased risk of developing SLE and/or to disease grading, staging, and/or prognosis.
    Type: Application
    Filed: May 31, 2017
    Publication date: November 30, 2017
    Applicant: CardioVax, LLC
    Inventors: Mark Carvlin, Jan Nilsson, Stacey Ruiz