Patents by Inventor Stacie Calad

Stacie Calad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250182848
    Abstract: Embodiments are directed to a method for determining relationships between genes, phenotypes, and diseases that includes extracting a first set of biological data containing gene data, phenotype data, and disease data from a database, extracting a second set of biological data from a database, creating nodes on a network pertaining to each individual gene, phenotype, and disease data extracted from one of a database and documents, training multiple machine learning (ML) algorithms on a set of extracted data with matching empirical results, using at least one of the ML algorithms and the second set of biological data for determining relationships between the nodes, creating at least one of a gene-disease association score, gene-phenotype association score, and disease-phenotype association score for the relationships based on the relative association of the nodes, and displaying at least one of the association scores to a user.
    Type: Application
    Filed: November 28, 2022
    Publication date: June 5, 2025
    Applicant: BioSymetrics, Inc.
    Inventors: Victoria M. Catterson, Nishanth Merwin, Shahrzad Hosseini Vajargah, Mikalai Malinouski, Stacie Calad-Thomson, Kevin C.H. Ha, Stephny Geread, Steven Bishop, Jonathan R. Volpatti, David Kokel, Gabriel Musso
  • Publication number: 20110230660
    Abstract: The present invention relates to a method comprising the step of contacting a protected N,N-bis(2-X-ethyl)amine with a (2-fluorophenyl)acetonitrile in the presence of a water-soluble phase transfer reagent, concentrated aqueous base, and an immiscible organic solvent, and under such conditions to form a 4-(2-fluorophenyl)-4-piperidinecarbonitrile in at least a 70% yield, wherein X is a leaving group. The 4-(2-fluorophenyl)-4-piperidinecarbonitrile is useful in preparing spiroindolines, which can be used as precursors of compounds that are modulators of CCR2 receptor.
    Type: Application
    Filed: December 3, 2009
    Publication date: September 22, 2011
    Inventors: Stacie Calad, Brian Daniel Doan