Patents by Inventor Stacie Casman

Stacie Casman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

Proteins and nucleic acids encoding same

Patent number: 7141549

Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Type: Grant

Filed: February 8, 2005

Date of Patent: November 28, 2006

Inventors: Peter Mezes, Luca Rastelli, John Herrmann, John MacDougall, Haihong Zhong, Stacie Casman, Ferenc Boldog, Richard Shimkets, Linda Gorman, Andrew Eisen, Steven Spaderna, Corine Vernet, Constance Berghs, Kimberly Spytek, Vincent DiPippo, Bryan Zerhusen, John Peyman, Karen Ellerman, David Stone, William Grosse, John Alsobrook, II, Denise Lepley, Daniel Rieger, Catherine Burgess, Shlomit Edinger, Edward Voss, Charles Miller
Novel proteins and nucleic acids encoding same

Publication number: 20060084054

Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Type: Application

Filed: June 4, 2003

Publication date: April 20, 2006

Inventors: John Alsobrook, David Anderson, Jason Baumgartner, Constance Berghs, Ferenc Boldog, Catherine Burgess, Stacie Casman, Elina Catterton, Mohanraj Dhanabal, Shlomit Edinger, Karen Ellerman, Seth Ettenberg, Esha Gangolli, Valerie Gerlach, Linda Gorman, William Grosse, Erik Gunther, Xiaojia Guo, Vladimir Gusev, John Herrmann, Weizhen Ji, Ramesh Kekuda, Nikolai Khramtsov, William LaRochelle, Li Li, Hongping Liang, Kenneth Low, John MacDougall, Timothy Maclachlan, Uriel Malyankar, Kelly McQueeney, Amanda Mezick, Charles Miller, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, John Peyman, Xiaozhong Qian, Luca Rastelli, Daniel Rieger, Mark Rothenberg, Suresh Shenoy, Richard Shimkets, Glennda Smithson, Kimberly Spytek, David Stone, Sujatha Sukumaran, Edward Szekeres, Corine Vernet, Edward Voss, Adam Wolenc, Mei Zhong, Haihong Zhong
Therapeutic polypeptides, nucleic acids encoding same, and methods of use

Publication number: 20060063200

Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Type: Application

Filed: February 2, 2005

Publication date: March 23, 2006

Applicant: CuraGen Corporation

Inventors: David Anderson, Jason Baumgartner, Ferenc Boldog, Stacie Casman, Shlomit Edinger, Esha Gangolli, Valerie Gerlach, Linda Gorman, Xiaojia Guo, Tord Hjalt, Ramesh Kekuda, Li Li, John MacDougall, Uriel Malyankar, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, Carol Pena, Luca Rastelli, Richard Shimkets, David Stone, Kimberly Spytek, Corine Vernet, Edward Voss, Bryan Zerhusen
Proteins and nucleic acids encoding same

Publication number: 20060013813

Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Type: Application

Filed: February 8, 2005

Publication date: January 19, 2006

Inventors: Peter Mezes, Luca Rastelli, John Herrmann, John MacDougall, Haihong Zhong, Stacie Casman, Frenc Boldog, Richard Shimkets, Linda Gorman, Andrew Eisen, Steven Spaderna, Corine Vernet, Constance Berghs, Kimberly Spytek, Vincent DiPippo, Bryan Zerhusen, John Peyman, Karen Ellerman, David Stone, William Grosse, John Alsobrook, Denise Lepley, Daniel Rieger, Catherine Burgess, Sholmit Edinger, Edward Voss, Charles Miller
Therapeutic polypeptides, nucleic acids encoding same, and methods of use

Publication number: 20060003323

Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Type: Application

Filed: June 3, 2003

Publication date: January 5, 2006

Inventors: John Alsobrook, Enrique Alvarez, David Anderson, Ferenc Boldog, Stacie Casman, Elina Catterton, Andrei Chapoval, Julie Crabtree-Bokor, Shlomit Edinger, Karen Ellerman, Seth Ettenberg, Esha Gangolli, Valerie Gerlach, Linda Gorman, Erik Gunther, Xiaojia (Sasha) Guo, Vladimir Gusev, John Herrmann, Weizhen Ji, Ramesh Kekuda, Li Li, Xiaohong Liu, John MacDougall, Timothy Machlachlan, Uriel Malyankar, Amanda Mezick, Isabelle Millet, Vishnu Mishra, Muralidhara Padigaru, Meera Patturajan, Carol Pena, John Peyman, Debasish Raha, Luca Rastelli, Daniel Rieger, Mark Rothenberg, Paul Sciore, Suresh Shenoy, Richard Shimkets, Glennda Smithson, Kimberly Spytek, David Stone, Corine Vernet, Edward Voss, Mei Zhong, Hiahong Zhong
Polypeptides and nucleic acids encoding same

Publication number: 20050260713

Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Type: Application

Filed: April 21, 2005

Publication date: November 24, 2005

Inventors: Esha Gangolli, Meera Patturajan, Corine Vernet, Uriel Malyankar, Ramesh Kekuda, David Stone, David Anderson, Richard Shimkets, Catherine Burgess, Bryan Zerhusen, Xiaohong Liu, Kimberly Spytek, Stacie Casman, Ference Boldog, Glennda Smithson, Li Li, Weizhen Ji, John MacDougall
Novel human proteins and polynucleotides encoding them

Publication number: 20050170380

Abstract: The present invention provides novel isolated SECX polynucleotides and the membrane-associated or secreted polypeptides encoded by the SECX polynucleotides. Also provided are the antibodies that immunospecifically bind to a SECX polypeptide or any derivative, variant, mutant or fragment of the SECX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the SECX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.

Type: Application

Filed: October 21, 2004

Publication date: August 4, 2005

Applicant: CuraGen Corporation

Inventors: Elma Fernandes, Corine Vernet, Richard Shimkets, David Anderson, Muralidhara Padigaru, Ferenc Boldog, Li Li, Suresh Shenoy, Stacie Casman, Luca Rastelli
Therapeutic polypeptides, nucleic acids encoding same, and methods of use

Publication number: 20050053930

Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Type: Application

Filed: June 3, 2003

Publication date: March 10, 2005

Inventors: David Anderson, Ferenc Boldog, Catherine Burgess, Stacie Casman, Shlomit Edinger, Andrew Eisen, Karen Ellerman, Valerie Gerlach, Linda Gorman, Xiaojia Guo, Vladimir Gusev, Weizhen Ji, Li Li, John MacDougall, Uriel Malyankar, Isabelle Millet, Tatiana Ort, Muralidhara Padigaru, Sudhirdas Prayaga, Meera Patturajan, Carol Pena, John Peyman, Daniel Rieger, Mark Rothenberg, Paul Sciore, Suresh Shenoy, Glennda Smithson, Kimberly Spytek, David Stone, Raymond Taupier, Velizar Tchernev, Corine Vernet, Edward Voss, Bryan Zerhusen, Mei Zhong
Therapeutic polypeptides, nucleic acids encoding same, and methods of use

Publication number: 20040229779

Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Type: Application

Filed: August 8, 2003

Publication date: November 18, 2004

Inventors: Ramesh Kekuda, Uriel Malyankar, Li Li, David Anderson, Xiaojia (Sasha) Guo, Mei Zhong, Muralidhara Padigaru, Stacie Casman, Ferenc Boldog, Charles Miller, Nikolai Khramtsov, Corine Vernet, Meera Patturajan
Therapeutic polypeptides, nucleic acids encoding same, and methods of use

Publication number: 20040162236

Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Type: Application

Filed: March 31, 2003

Publication date: August 19, 2004

Inventors: John Alsobrook, Patricia Bento, Ferenc Boldog, Catherine Burgess, Stacie Casman, Julie Crabtree Bokor, Shlomit R. Edinger, Karen Ellerman, Elma Fernandes, Valerie Gerlach, William Grosse, Erik Gunther, Vladimir Gusev, Melvyn Heyes, Denise Lepley, Li Li, John R. MacDougall, Uriel M. Malyankar, Isabelle Millet, Meera Patturajan, John A. Peyman, Luca Rastelli, Daniel Rieger, Suresh Shenoy, Richard Shimkets, Glennda Smithson, David Stone, Corine Vernet, Edward Voss
Novel proteins and nucleic acids encoding same

Publication number: 20040043930

Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Type: Application

Filed: March 31, 2003

Publication date: March 4, 2004

Inventors: David W. Anderson, Patricia Bento, Ferenc Boldog, Catherine Burgess, Stacie Casman, Katarzyna Furtak, Linda Gorman, Bonnie Gould-Rothberg, Erik Gunther, Melvyn Heyes, Li Li, Kimberly Spytek, David Stone, Mei Zhong, Uriel Malyankar, Shlomit Edinger, Meera Patturajan, Mark Rothenberg, Glennda Smithson
Therapeutic polypeptides, nucleic acids encoding same, and methods of use

Publication number: 20040029150

Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Type: Application

Filed: March 31, 2003

Publication date: February 12, 2004

Inventors: John Alsobrook, David Anderson, Ferenc Boldog, Catherine Burgess, Stacie Casman, Shlomit R. Edinger, Valerie Gerlach, William Grosse, Xiaojia Guo, Vladimir Gusev, Weizhen Ji, William LaRochelle, Denise Lepley, Li Li, Xiaohong Liu, John R. MacDougall, Uriel M. Malyankar, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, John A. Peyman, Luca Rastelli, Daniel Rieger, Mark E. Rothenberg, Richard Shimkets, David J. Stone, Raymond Taupier, Corine Vernet, Bryan Zerhusen
Novel human proteins, polynucleotides encoding them and methods of using the same

Publication number: 20040024181

Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Type: Application

Filed: October 26, 2001

Publication date: February 5, 2004

Inventors: Esha A. Gangolli, Kimberly A. Spytek, Jennifer Gilbert, Stacie Casman, Angela Blalock, Li Li, Corine Vernet, Suresh Shenoy, Vishnu S. Mishra, Katarzyna Furtak, Valerie L. Gerlach, Shlomit Edinger, Uriel Malyanker, David Stone, Isabelle Millet, Glennda Smithson, Erik Gunther, Karen Ellerman, Muralidhara Padigaru, Raymond J. Taupier, David W. Anderson
Novel proteins and nucleic acids encoding same

Publication number: 20030216545

Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Type: Application

Filed: September 27, 2001

Publication date: November 20, 2003

Inventors: Kimberly A. Spytek, Stacie Casman, Muralidhara Padigaru, Kevin S. Dickson, Corine Vernet, Steven K. Spaderna, Suresh G. Shenoy, Valerie Gerlach, Karen Ellerman, Shlomit Edinger, John R. MacDougall, Glennda Smithson, Li Li, Uriel M. Malyankar, Sarah Taylor, Erik Gunther, Velizar T. Tchernev
Novel proteins and nucleic acids encoding same

Publication number: 20030211485

Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Type: Application

Filed: May 29, 2002

Publication date: November 13, 2003

Inventors: Valerie L. Gerlach, John R. MacDougall, David J. Stone, Glennda Smithson, Muralidhara Padigaru, Catherine Burgess, Corine Vernet, Elma Fernandes, Richard A. Shimkets, Velizar T. Tchernev, Vishnu Mishra, Stacie Casman, Kimberly A. Spytek, Bryan Zerhusen
Novel proteins and nucleic acids encoding same

Publication number: 20030212255

Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and TRA 1536859v1 antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Type: Application

Filed: July 25, 2001

Publication date: November 13, 2003

Inventors: Muralidhara Padigaru, Peter Mezes, Vishnu Mishra, Catherine Burgess, Stacie Casman, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Valerie L. Gerlach, John R. MacDougall, Glennda Smithson
Novel proteins and nucleic acids encoding same

Publication number: 20030195335

Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Type: Application

Filed: January 11, 2002

Publication date: October 16, 2003

Inventors: William M. Grosse, Edward S. Szekeres, Stacie Casman, John P. Alsobrook, Catherine E. Burgess, Muralidhara Padigaru, Sarah Taylor, Velizar T. Tchernev, Kimberly A. Spytek, Li Li, Suresh Shenoy, Ramesh Kekuda, Esha A. Gangolli, David J. Stone, Glennda Smithson, John R. MacDougall
Novel proteins and nucleic acids encoding same

Publication number: 20030165829

Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Type: Application

Filed: February 27, 2001

Publication date: September 4, 2003

Inventors: Muralidhara Padigaru, Kumud Majumder, Catherine E. Burgess, Corine A.M. Vernet, Elma R. Fernandes, Richard A. Shimkets, Velizar T. Tchernev, Vishnu Mishra, Stacie Casman, Kimberly A. Spytek, Bryan D. Zerhusen