Patents by Inventor Stacie Marie Halbert

Stacie Marie Halbert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protease inhibitors
    Publication number: 20020049316
    Abstract: The present invention provides compounds of formula (I) which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods for treating diseases of excessive bone loss or cartilage or matrix degradation, including osteoporosis; gingival disease including gingivitis and periodontitis; arthritis, more specifically, osteoarthritis and rheumatoid arthritis; Paget's disease; hypercalcemia or malignancy; and metabolic bone disease therewith.
    Type: Application
    Filed: December 17, 2001
    Publication date: April 25, 2002
    Inventors: Stacie Marie Halbert, Evelyne Michaud, Scott Kevin Thompson, Daniel Frank Veber
  • Protease inhibitors
    Patent number: 6331542
    Abstract: The present invention provides compounds which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods for treating diseases of excessive bone loss or cartilage or matrix degradation, including osteoporosis; gingival disease including gingivitis and periodontitis; arthritis, more specifically, osteoarthritis and rheumatoid arthritis; Paget's disease; hypercalcemia of malignancy; and metabolic bone disease, comprising inhibiting said bone loss or excessive cartilage or matrix degradation by administering to a patient in need thereof a compound of the present invention.
    Type: Grant
    Filed: April 19, 2000
    Date of Patent: December 18, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Thomas Joseph Carr, Renee Louise Desjarlais, Timothy Francis Gallagher, Stacie Marie Halbert, Hye-Ja Oh, Scott Kevin Thompson, Daniel Frank Veber, Dennis Shinji Yamashita, Jack Hwekwo Yen
  • Carbohydrazide protease inhibitors
    Patent number: 6284777
    Abstract: The present invention provides compounds which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods for treating diseases of excessive bone loss or cartilage or matrix degradation, inducing osteoporosis; gingival disease including gingivitis and periodontists; arthritis, more specifically, osteoarthritis and rheumatoid arthritis; Paget's disease; hypercalcemia of malignancy; and metabolic bone disease, comprising inhibiting said bone loss or excessive cartilage or matrix degradation by administering to a patient in need thereof a compound of the present invention.
    Type: Grant
    Filed: April 19, 2000
    Date of Patent: September 4, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Stacie Marie Halbert, Scott Kevin Thompson
  • Protease inhibitors
    Patent number: 6232342
    Abstract: The present invention provides compounds which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods for treating diseases of excessive bone loss or cartilage or matrix degradation, including osteoporosis; gingival disease including gingivitis and periodontitis; arthritis, more specifically, osteoarthritis and rheumatoid arthritis; Paget's disease, hypercalcemia of malignancy; and metabolic bone disease, comprising inhibiting and bone loss or excessive cartilage or matrix degradation by administering to a patient in need thereof a compound of the present invention.
    Type: Grant
    Filed: June 11, 1999
    Date of Patent: May 15, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Thomas Joseph Carr, Renee Louise Desjarlais, Timothy Francis Gallagher, Stacie Marie Halbert, Hye-Ja Oh, Scott Kevin Thompson, Daniel Frank Veber, Dennis Shinji Yamashita, Jack Hwekwo Yen
  • Protease inhibitors
    Patent number: 5998470
    Abstract: Disclosed herein is a compound of the formula ##STR1## known as 2-[N-(N-benzyloxycarbonyl-L-leucinyl)]-2'-[N'-[4-(N,N-dimethylaminomethyl) benzyloxy]carbonyl-L-leucinyl]carbohydrazide; and pharmaceutically acceptable salts, hydrates and solvates thereof.
    Type: Grant
    Filed: April 13, 1999
    Date of Patent: December 7, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Stacie Marie Halbert, Scott Kevin Thompson, Daniel Frank Veber
  • Compounds
    Patent number: 5684032
    Abstract: This invention relates to novel carboxylic acid indole compounds and compositions for use in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
    Type: Grant
    Filed: October 5, 1995
    Date of Patent: November 4, 1997
    Assignee: SmithKline Beecham Corporation
    Inventors: John Duncan Elliott, Jack Dale Leber, Scott Kevin Thompson, Stacie Marie Halbert