Abstract: A photon-counting detector includes a first subset of detector modules and at least one second subset of detector modules. Each detector module has power-consuming circuitry. Power-consuming circuitry of detector modules in the first subset is configured, in an operational mode in which the detector modules are powered on, to consume a first amount of power. Correspondingly, power-consuming circuitry of detector modules in the at least one second subset is configured, in the operational mode, to consume a second amount of power that is lower than the first amount of power.

Abstract: Disclosed is an edge-on photon counting detector and a method for manufacturing a charge collecting side of such detector. The edge-on photon counting detector comprises a semi-conducting substrate. The semi-conducting substrate comprises, a first end adapted to face an x-ray source and a second end opposite the first end in the direction of incoming x-rays, and at least one strip having N depth segments, N?2, each of the depth segments comprising a charge collecting metal electrode and a charge collecting side comprising doped regions and insulating regions, wherein each of the charge collecting metal electrodes is arranged over a corresponding doped region and is connected to a respective routing trace arranged on the insulating regions, the respective routing trace being adapted to conduct signals from the charge collecting metal electrode to a read-out pad E, connectable to front-end electronics, arranged at the second end.

Abstract: An X-ray detector system includes a photon-counting detector with multiple detector modules including a respective power-consuming circuitry. At least some of the detector modules include a temperature sensor to monitor a temperature on the detector module and generate a temperature representing signal. A detector controller selectively switches, for at least a subset of the detector modules, the detector modules between an idle mode in which at least a respective part of the detector modules is powered off and an operational mode in which the detector modules are powered on. The power-consuming circuitries of the at least a subset of detector modules generate calibration data based on the temperature representing signals to correct for any temperature-induced changes to image data generated by the photon-counting detector.

Abstract: There is provided a detector module (1) for a modular x-ray detector, wherein the detector module (1) includes multiple x-ray detector substrates (10) and associated anti-scatter collimators (20). Each x-ray detector substrate (10) has a number of detector diodes, and each x-ray detector substrate has an associated anti-scatter collimator (20). Each x-ray detector substrate (10) has an integrated circuit (30) for collecting x-ray signals from the diodes attached to the x-ray detector substrate at the bottom of the x-ray detector substrate assuming the top is where the x-rays enter, and the associated anti-scatter collimator (20) is placed above the integrated circuit (30).

Abstract: Disclosed is a detector system for x-ray imaging. The detector system includes a detector having a plurality of edge-on detector modules. Each of the edge-on detector modules includes a first edge that is adapted to be oriented towards an x-ray source and a front-side running essentially parallel to the direction of incoming x-rays. The front-side includes at least one charge collecting electrode. At least a subset of the plurality of edge-on detector modules being pairwise arranged, front-side to front-side, whereby a front-side to front-side gap is defined between the front-sides of the pairwise arranged edge-on detector modules. The pairwise arranged edge-on detector modules are associated with an anti-scatter collimator arranged in the x-ray path between the x-ray source and the edge-on detector modules and overlapping the front-side to front-side gap.

Abstract: Disclosed is an edge-on photon counting detector and a method for manufacturing a charge collecting side of such detector. The edge-on photon counting detector comprises a semi-conducting substrate. The semi-conducting substrate comprises, a first end adapted to face an x-ray source and a second end opposite the first end in the direction of incoming x-rays, and at least one strip having N depth segments, N?2, each of the depth segments comprising a charge collecting metal electrode and a charge collecting side comprising doped regions and insulating regions, wherein each of the charge collecting metal electrodes is arranged over a corresponding doped region and is connected to a respective routing trace arranged on the insulating regions, the respective routing trace being adapted to conduct signals from the charge collecting metal electrode to a read-out pad E, connectable to front-end electronics, arranged at the second end.

Abstract: Disclosed is an edge-on photon counting detector and a method for manufacturing a charge collecting side of such detector. The edge-on photon counting detector includes a semi-conducting substrate. The semi-conducting substrate includes, a first end adapted to face an x-ray source and a second end opposite the first end in the direction of incoming x-rays, and at least one strip having N depth segments, N?2, each of the depth segments including a charge collecting metal electrode and a charge collecting side including doped regions and insulating regions, wherein each of the charge collecting metal electrodes is arranged over a corresponding doped region and is connected to a respective routing trace arranged on the insulating regions, the respective routing trace being adapted to conduct signals from the charge collecting metal electrode to a read-out pad E, connectable to front-end electronics, arranged at the second end.

Abstract: Disclosed is an edge-on photon counting detector and a method for manufacturing a charge collecting side of such detector. The edge-on photon counting detector includes a semi-conducting substrate. The semi-conducting substrate includes, a first end adapted to face an x-ray source and a second end opposite the first end in the direction of incoming x-rays, and at least one strip having N depth segments, N?2, each of the depth segments including a charge collecting metal electrode and a charge collecting side including doped regions and insulating regions, wherein each of the charge collecting metal electrodes is arranged over a corresponding doped region and is connected to a respective routing trace arranged on the insulating regions, the respective routing trace being adapted to conduct signals from the charge collecting metal electrode to a read-out pad E, connectable to front-end electronics, arranged at the second end.

Abstract: Disclosed is a detector system for x-ray imaging. The detector system includes a detector having a plurality of edge-on detector modules. Each of the edge-on detector modules includes a first edge that is adapted to be oriented towards an x-ray source and a front-side running essentially parallel to the direction of incoming x-rays. The front-side includes at least one charge collecting electrode. At least a subset of the plurality of edge-on detector modules being pairwise arranged, front-side to front-side, whereby a front-side to front-side gap is defined between the front-sides of the pairwise arranged edge-on detector modules. The pairwise arranged edge-on detector modules are associated with an anti-scatter collimator arranged in the x-ray path between the x-ray source and the edge-on detector modules and overlapping the front-side to front-side gap.

Abstract: An X-ray detector system includes a photon-counting detector with multiple detector modules including a respective power-consuming circuitry. At least some of the detector modules include a temperature sensor to monitor a temperature on the detector module and generate a temperature representing signal. A detector controller selectively switches, for at least a subset of the detector modules, the detector modules between an idle mode in which at least a respective part of the detector modules is powered off and an operational mode in which the detector modules are powered on. The power-consuming circuitries of the at least a subset of detector modules generate calibration data based on the temperature representing signals to correct for any temperature-induced changes to image data generated by the photon-counting detector.

Abstract: A photon-counting detector includes a first subset of detector modules and at least one second subset of detector modules. Each detector module has power-consuming circuitry. Power-consuming circuitry of detector modules in the first subset is configured, in an operational mode in which the detector modules are powered on, to consume a first amount of power. Correspondingly, power-consuming circuitry of detector modules in the at least one second subset is configured, in the operational mode, to consume a second amount of power that is lower than the first amount of power.

Abstract: The proposed technology relates to an x-ray detector arrangement having x-ray detector sub-modules arranged in two or more layers, where the separation between adjacent sub-modules in a lower layer is smaller than the corresponding separation between sub-modules in an upper layer.

Abstract: There is provided a detector module (1) for a modular x-ray detector, wherein the detector module (1) includes multiple x-ray detector substrates (10) and associated anti-scatter collimators (20). Each x-ray detector substrate (10) has a number of detector diodes, and each x-ray detector substrate has an associated anti-scatter collimator (20). Each x-ray detector substrate (10) has an integrated circuit (30) for collecting x-ray signals from the diodes attached to the x-ray detector substrate at the bottom of the x-ray detector substrate assuming the top is where the x-rays enter, and the associated anti-scatter collimator (20) is placed above the integrated circuit (30).

Abstract: The proposed technology relates to an x-ray detector arrangement having x-ray detector sub-modules arranged in two or more layers, where the separation between adjacent sub-modules in a lower layer is smaller than the corresponding separation between sub-modules in an upper layer.

Abstract: A guide wire assembly includes a proximal end portion, a distal portion comprising a coil, a hollow stranded wire extending towards the distal portion, and a core wire. The guide wire assembly is characterized in that a proximal tube is provided, which extends from the proximal end portion to a proximal end of the hollow stranded wire such that the hollow stranded wire is directly joined to the proximal tube. The core wire extends into the distal portion and does not extend into the proximal tube. An entire length of the hollow stranded wire is in a range of 7.5 to 22.5% of an entire length of the guide wire assembly.

Abstract: A Silicon detector for x-ray imaging is based on multiple semiconductor detector modules (A) arranged together to form an overall detector area, where each semiconductor detector module includes an x-ray sensor of crystalline Silicon oriented edge-on to incoming x-rays and connected to integrated circuitry for registration of x-rays interacting in the x-ray sensor through the photoelectric effect and through Compton scattering and for an incident x-ray energy between 40 keV and 250 keV to provide the spatial and energy information from these interactions to enable an image of an object. Further, anti-scatter modules (B) are interfolded between at least a subset of the semiconductor detector modules to at least partly absorb Compton scattered x-rays.

Abstract: Sensor and guide wire assembly (1; 21) for intravascular measurement of physical variables inside a living body and comprises a proximal end portion (2; 22) and a sensor element (9; 29), which is located in a distal portion of the sensor and guide wire assembly (1; 21), and is characterized in that a proximal tube (3; 23) is provided, which extends from said proximal portion (2; 22) to a proximal end of a hollow stranded wire (4; 24), which extends to the distal end portion wherein the sensor element (9; 29) is located.

Abstract: Sensor and guide wire assembly (1; 21) for intravascular measurement of physical variables inside a living body and comprises a proximal end portion (2; 22) and a sensor element (9; 29), which is located in a distal portion of the sensor and guide wire assembly (1; 21), and is characterized in that a proximal tube (3; 23) is provided, which extends from said proximal portion (2; 22) to a proximal end of a hollow stranded wire (4; 24), which extends to the distal end portion wherein the sensor element (9; 29) is located.

Abstract: Compounds of formula (I) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.

Abstract: Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.