Abstract: A machine for manufacturing air pillows from plastic bags includes a frame, a conveyor mechanism, and an air inflating mechanism. The conveyor mechanism includes a motor, a first conveyor linked to the motor and supported in a compartment of the frame, and a second conveyor driven by the first conveyor and supported at a sidewall of the frame out of the compartment for guiding and conveying the plastic bags. The second conveyor has a conveying clearance for fitting the plastic bag when the plastic bags are conveyed by the second conveyor. The air inflating mechanism includes a sealing unit for sealing an opening of the plastic bag and an air needle protruded from the sidewall of the frame for inflating the plastic bag before the opening of the plastic bag is sealed.