Abstract: Wide-spread application of screening colonoscopy is increasing the detection of T1 cancers. These superficial cancers are treated with endoscopic resection as first-line treatment; offering potentially curative, organ-preserving minimally invasive treatment for early cancer. Pathological examination of the tumor determines histological criteria associated with an increased risk of lymph node metastasis. Therefore, their presence justifies an additional radical surgery but results in perioperative complications as well as post-operative mortality. These pejorative histological criteria are detected in half of the patients however overall incidence of lymph node metastasis is only of 20%. Therefore, organ preservation could be offered to a larger number of patients if new biomarkers could complete the tumor histological evaluation.

Abstract: A device for protecting against an airborne contamination of a medical device including an air circulation cooling system is disclosed. The device also includes an enclosure defining a sealed receiving volume for the medical device, the protection device further comprising structure for circulating gas flow, within the enclosure, the gas flow having predetermined composition and/or quality criteria different from the external environment and able to be used by the cooling system of the medical device in operation.