Patents by Inventor Stanislav Jaracz
Stanislav Jaracz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20170258693Abstract: The disclosure provides oral care compositions comprising zinc ions and citrate ions with molar ratios which unexpectedly high zinc bioavailability, together with methods of preparing and using the same.Type: ApplicationFiled: December 15, 2015Publication date: September 14, 2017Applicant: Colgate-Palmolive CompanyInventors: Stanislav JARACZ, Harsh M. TRIVEDI, Lyndsay SCHAEFFER-KORBYLO
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Publication number: 20170113989Abstract: Disclosed herein are improved methods for the synthesis of honokiol, as well as methods for the synthesis of 3,3?-di-tert-butyl-5,5?-dimethyl-[1,1?-biphenyl]-2,4?-diol, 3?,5-dimethyl-[1,1?-biphenyl]-2,4?-diol, and 2,4?-dimethoxy-3?,5-dimethyl-1,1?-biphenyl, 3,3?,5,5?-tetra-tert-butyl-[1,1?-biphenyl]-2,4?-diol, and certain tetrasubstituted bisphenols, and uses therefor.Type: ApplicationFiled: October 21, 2016Publication date: April 27, 2017Inventors: Stanislav JARACZ, Marisa KOZLOWSKI, Young EUN LEE, Sun Min KIM
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Patent number: 9625449Abstract: An in vitro method for determining the bioavailability of zinc (II) ions from an oral care composition comprises: providing a sample comprising, the oral care composition; contacting the sample with a biorelevant substrate, separating the biorelevant substrate from the sample, contacting the biorelevant substrate with an indicator under conditions selected such that the indicator is capable of reacting with zinc (II) ions, and determining a light absorbance of the indicator. The indicator is zincon or a salt thereof. The method is useful for estimating the ability of an oral care composition to deliver therapeutically-active zinc (II) ions to the oral cavity. Also provided is the use of zincon and a biorelevant substrate in vitro to determine the bioavailability of zinc (II) ions from an oral care composition comprising, a zinc source.Type: GrantFiled: December 23, 2014Date of Patent: April 18, 2017Assignee: Colgate-Palmolive CompanyInventors: Stanislav Jaracz, Harsh M. Trivedi, Lyndsay Schaeffer-Korbylo, Lynette Zaidel
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Publication number: 20170020795Abstract: Described herein are compositions comprising combinations of metal salts, and methods of preparing and using the same.Type: ApplicationFiled: October 6, 2016Publication date: January 26, 2017Inventors: Venda Porter Maloney, Vyoma Patel, Steven Wade Fisher, Andre Michelle Morgan, Michael Prencipe, Stanislav Jaracz
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Patent number: 9486396Abstract: Described herein are compositions comprising combinations of metal salts, and methods of preparing and using the same.Type: GrantFiled: December 21, 2010Date of Patent: November 8, 2016Assignee: Colgate-Palmolive CompanyInventors: Venda Porter Maloney, Vyoma Patel, Steven Wade Fisher, Andre Michelle Morgan, Michael Prencipe, Stanislav Jaracz
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Patent number: 9439843Abstract: The invention provides oral care compositions comprising isobutyl magnolol and propylene glycol monolaurate, together with methods of making and using the same. Also described is a method of enhancing the solubility of isobutyl magnolol in an oral care composition comprising effective amount of propylene glycol monolaurate. The composition is for use in the treatment of caries, gingivitis, periodontitis, tooth yellowing and halitosis.Type: GrantFiled: December 2, 2011Date of Patent: September 13, 2016Assignee: Colgate-Palmolive CompanyInventors: Lin Fei, Stanislav Jaracz, Ying Yang, Guofeng Xu
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Patent number: 9435745Abstract: A method of measuring the relative rates of release of a target metal ion from two or more samples includes: (i) providing at least two aliquots of a solution including an indicator, the indicator having a color; (ii) dispersing a sample into each aliquot; and (iii) during step (ii), monitoring the color of the indicator in situ to determine the rates of release of the target metal ions from the samples relative to one another. Each sample includes at least one source of the target metal ion. The indicator contains zincon. The samples are oral care compositions selected from a toothpaste, a tooth gel, and a tooth powder. The target metal ion is selected from the stannous and zinc (II).Type: GrantFiled: December 23, 2014Date of Patent: September 6, 2016Assignee: Colgate-Palmolive CompanyInventors: Stanislav Jaracz, Ravi Subramanyam, Michael Prencipe
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Publication number: 20160178527Abstract: A method of measuring the relative rates of release of a target metal ion from two or more samples includes: (i) providing at least two aliquots of a solution including an indicator, the indicator having a colour; (ii) dispersing a sample into each aliquot; and (iii) during step (ii), monitoring the colour of the indicator in situ to determine the rates of release of the target metal ions from the samples relative to one another. Each sample comprises at least one source of the target metal ion. The indicator comprises zincon. The samples are oral care compositions selected from a toothpaste, a tooth gel, and a tooth powder. The target metal ion is selected from the stannous and zinc (II).Type: ApplicationFiled: December 23, 2014Publication date: June 23, 2016Inventors: Stanislav Jaracz, Ravi Subramanyam, Michael Prencipe
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Publication number: 20160178595Abstract: A method of detecting stannous ions that includes providing a zincon-containing indicator having a colour, contacting the indicator with a sample, and detecting any resulting change in the colour of the indicator, wherein a change in the colour of the indicator from the colour to colourless indicates that stannous ions are present in the sample. The method is useful for the analysis of oral care compositions. Also provided is the use of zinc on as an indicator for detecting stannous ions.Type: ApplicationFiled: December 23, 2014Publication date: June 23, 2016Inventors: Stanislav Jaracz, Michael Prencipe
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Publication number: 20160178617Abstract: An in vitro method for determining the bioavailability of zinc (II) ions from an oral care composition comprises: providing a sample comprising, the oral care composition; contacting the sample with a biorelevant substrate, separating the biorelevant substrate from the sample., contacting the biorelevant substrate with an indicator under conditions selected such that the indicator is capable of reacting with zinc (II) ions, and determining a light absorbance of the indicator. The indicator is zincon or a salt thereof. The method is useful for estimating the ability of an oral care composition to deliver therapeutically-active zinc (II) ions to the oral cavity. Also provided is the use of zincon and a biorelevant substrate in vitro to determine the bioavailability of zinc (II) ions from an oral care composition comprising, a zinc source.Type: ApplicationFiled: December 23, 2014Publication date: June 23, 2016Inventors: Stanislav Jaracz, Harsh M. Trivedi, Lyndsay Schaeffer-Korbylo, Lynette Zaidel
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Patent number: 9370475Abstract: Oral care compositions comprising isobutyl magnolol and n-butyl magnolol. A method of enhancing the solubility of isobutyl magnolol in an oral care composition comprises admixing n-butyl magnolol with an orally acceptable carrier comprising isobutyl magnolol. The composition may be used to treat diseases or conditions of the oral cavity such as caries, gingivitis, periodontitis, tooth yellowing and halitosis.Type: GrantFiled: December 2, 2011Date of Patent: June 21, 2016Assignee: Colgate-Palmolive CompanyInventors: Lin Fei, Stanislav Jaracz, Ying Yang, Guofeng Xu
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Patent number: 9354219Abstract: A method of detecting stannous ions that includes providing a zincon-containing indicator having a color, contacting the indicator with a sample, and detecting any resulting change in the color of the indicator, wherein a change in the color of the indicator from the color to colorless indicates that stannous ions are present in the sample. The method is useful for the analysis of oral care compositions. Also provided is the use of zinc on as an indicator for detecting stannous ions.Type: GrantFiled: December 23, 2014Date of Patent: May 31, 2016Assignee: Colgate-Palmolive CompanyInventors: Stanislav Jaracz, Michael Prencipe
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Patent number: 9119879Abstract: Described herein are compositions comprising a quinone and one or more antibacterial agents, and methods of preparing and using the same.Type: GrantFiled: December 7, 2010Date of Patent: September 1, 2015Assignee: Colgate-Palmolive CompanyInventors: Laurence Du-Thumm, Lyndsay Schaeffer-Korbylo, David Santos, Stanislav Jaracz
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Publication number: 20150004104Abstract: Described herein are compositions comprising isopropyl magnolol; a surfactant system; and an orally acceptable carrier, together with methods of making and using the same.Type: ApplicationFiled: March 2, 2012Publication date: January 1, 2015Applicant: Colgate-Palmolive CompanyInventors: Lin Fei, Stanislav Jaracz, Ying Yang, Geofeng Xu
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Publication number: 20140356299Abstract: The invention provides oral care compositions comprising isobutyl magnolol and propylene glycol monolaurate, together with methods of making and using the same. Also described is a method of enhancing the solubility of isobutyl magnolol in an oral care composition comprising effective amount of propylene glycol monolaurate. The composition is for use in the treatment of caries, gingivitis, periodontitis, tooth yellowing and halitosis.Type: ApplicationFiled: December 2, 2011Publication date: December 4, 2014Applicant: Colgate-Palmolive CompanyInventors: Lin Fei, Stanislav Jaracz, Ying Yang, Guofeng Xu
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Publication number: 20140314688Abstract: Oral care compositions comprising isobutyl magnolol and n-butyl magnolol. A method of enhancing the solubility of isobutyl magnolol in an oral care composition comprises admixing n-butyl magnolol with an orally acceptable carrier comprising isobutyl magnolol. The composition may be used to treat diseases or conditions of the oral cavity such as caries, gingivitis, periodontitis, tooth yellowing and halitosis.Type: ApplicationFiled: December 2, 2011Publication date: October 23, 2014Applicant: COLGATE-PALMOLIVE COMPANYInventors: Lin Fei, Stanislav Jaracz, Ying Yang, Guofeng Xu
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Patent number: 8852559Abstract: A stabilized oral care composition comprising a borinic acid derivative, e.g., a borinic ester.Type: GrantFiled: June 3, 2010Date of Patent: October 7, 2014Assignee: Colgate-Palmolive CompanyInventors: Venda Porter, Andre Morgan, Stanislav Jaracz, Jennifer Gronlund, Guofeng Xu, Donghui Wu, Michael Prencipe, Ravi Subramanyam
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Publication number: 20130287709Abstract: Described herein are compositions comprising combinations of metal salts, and methods of preparing and using the same.Type: ApplicationFiled: December 21, 2010Publication date: October 31, 2013Applicant: Colgate-Palmolive CompanyInventors: Venda Porter Maloney, Vyoma Patel, Steven Wade Fisher, Andre Michelle Morgan, Michael Prencipe, Stanislav Jaracz
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Publication number: 20130272972Abstract: Described herein are compositions comprising a quinone and one or more antibacterial agents, and methods of preparing and using the same.Type: ApplicationFiled: December 7, 2010Publication date: October 17, 2013Applicant: Colgate-Palmolive CompanyInventors: Laurence Du-Thumm, Lyndsay Schaeffer- Korbylo, David Santos, Stanislav Jaracz
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Publication number: 20130164228Abstract: Described herein are compositions for topical use comprising an antibacterially effective concentration of a gallate or gallamide compound which is a polysubstituted cycloalkyl or heterocycloalkyl wherein the substituents are selected from hydroxy, hydroxymethyl, fluoro, chloro, amino, nitro, or a moiety of formula -X-(CO)-(3,4,5-trihydroxyphenyl), wherein X is selected from O and NH, provided that the substituents comprise at least two moieties of formula -X-(CO)-(3,4,5-trihydroxyphenyl) attached to adjacent carbons in free or in orally or topically acceptable salt form, as well as methods of making and using the same.Type: ApplicationFiled: December 21, 2011Publication date: June 27, 2013Applicant: Colgate-Palmolive CompanyInventors: Stanislav Jaracz, Guofeng Xu, Steven Miller, Leonora Leigh, Guillaume Picquet, Laurence Du-Thumm