Patents by Inventor Stanislav POSPÍSIL

Stanislav POSPÍSIL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210263173
    Abstract: The investigated object containing a source of positrons is placed into a system of n position and energy-sensitive gamma radiation detectors (Di), each having detection elements (Dijk), where one of a pair of annihilation photons interacts in the detection element (D1jk) and the other interacts in another detection element (D2jk). The detectors store the coordinates of simultaneously affected detector elements, the time of interactions and the energies E1 and E2 of the annihilation photons. The recorded events in the detection elements (D1jk) and (D2jk) leads to recognition of individual pairs of annihilation photons. An analysis is performed of the registration of the photons by the detection elements (D1jk) and (D2jk) with energies in the interval from 507 keV to 513 keV to obtain an approximate spatial depiction of positions of positron annihilation and, registration of the photons from the positron annihilation with significantly Doppler shifted energies outside of that interval.
    Type: Application
    Filed: April 29, 2021
    Publication date: August 26, 2021
    Applicant: CZECH TECHNICAL UNIVERSITY IN PRAGUE, INSTITUTE OF EXPERIMENTAL AND APPLIED PHYSICS
    Inventors: Claude LEROY, Stanislav POSPÍSIL
  • Patent number: 9447062
    Abstract: A manumycin-type metabolite called Colabomycin E which inhibits caspase 1 and creation of interleukins, strain produces the Colabomycin E and a method of a production of the Colabomycin E. Colabomycin E is a new member of the manumycin-type metabolites produced by the strain Streptomyces aureus SOK1/5-04 deposited in The Czech collection of microorganisms under number CCM8556. The structure of 5 is similar to that of the already known metabolite colabomycin A (3) isolated from Streptomyces griseoflavus. However, the upper polyene chain of 5 is two carbons longer. Therefore, it was named Colabomycin E. Biological activity assays indicated that colabomycin E significantly inhibited IL-1? release from THP-1 cells and might thus potentially act as an anti-inflammatory agent.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: September 20, 2016
    Assignees: BIOLOGY CENTRE AS CR, V.V.I., INSTITUTE OF MICROBIOLOGYH AS CR, V.V.I., INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE
    Inventors: Miroslav Petricek, Katerina Petrickova, Stanislav Pospisil, Marek Kuzma, Alica Chronakova, Vaclav Kristufek, Ilja Striz
  • Publication number: 20160168106
    Abstract: A manumycin-type metabolite called Colabomycin E which inhibits caspase 1 and creation of interleukins, strain produces the Colabomycin E and a method of a production of the Colabomycin E. Colabomycin E is a new member of the manumycin-type metabolites produced by the strain Streptomyces aureus SOK1/5-04 deposited in The Czech collection of microorganisms under number CCM8556. The structure of 5 is similar to that of the already known metabolite colabomycin A (3) isolated from Streptomyces griseoflavus. However, the upper polyene chain of 5 is two carbons longer. Therefore, it was named Colabomycin E. Biological activity assays indicated that colabomycin E significantly inhibited IL-1? release from THP-1 cells and might thus potentially act as an anti-inflammatory agent.
    Type: Application
    Filed: December 15, 2014
    Publication date: June 16, 2016
    Applicants: BIOLOGY CENTRE AS CR, v. v. i.,, INSTITUTE OF MICROBIOLOGY AS CR, v. v. i., INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE
    Inventors: Miroslav Petricek, Katerina Petrickova, Stanislav Pospisil, Marek Kuzma, Alica Chronakova, Vaclav Kristufek, Ilja Striz
  • Publication number: 20140027648
    Abstract: The invention relates to a neutron detector (1) comprising a semiconductor detector substrate (10) and a conductive neutron converting layer (20), such as of TiB2. The neutron detector (1) thereby comprises a conductive contact made of a neutron conversion material (20).
    Type: Application
    Filed: May 2, 2012
    Publication date: January 30, 2014
    Inventors: Sture Petersson, Göran Thungström, Stanislav Pospisil, Tomas Slavicek, David Krapohl
  • Patent number: 8168953
    Abstract: A method and an apparatus for measuring the dose, the dose rate and/or the composition of radiation is disclosed. In the method, a detector means is exposed to a radiation environment, the detector means comprising an array of radiation sensing detector elements. The detector means is switched in a sensitive state for the duration of a sensitive time period, and during said sensitive time period, an interaction pattern generated by individual radiation quanta interacting with one or more of the detector elements is recorded. The duration of the sensitive time period can be precisely adapted to the intensity of the radiation that has to be recorded. The interaction pattern is analyzed to distinguish individual radiation quanta received during the sensitive time period, and a radiation category is assigned to each of the distinguished radiation quanta based on its corresponding interaction pattern.
    Type: Grant
    Filed: May 23, 2011
    Date of Patent: May 1, 2012
    Assignees: CERN-European Organization for Nuclear Research, Czech Technical University of Prague
    Inventors: Erik Henricus M. Heijne, Stanislav Pospisil
  • Publication number: 20120006991
    Abstract: A method and an apparatus for measuring the dose, the dose rate and/or the composition of radiation is disclosed. In the method, a detector means is exposed to a radiation environment, the detector means comprising an array of radiation sensing detector elements. The detector means is switched in a sensitive state for the duration of a sensitive time period, and during said sensitive time period, an interaction pattern generated by individual radiation quanta interacting with one or more of the detector elements is recorded. The duration of the sensitive time period can be precisely adapted to the intensity of the radiation that has to be recorded. The interaction pattern is analyzed to distinguish individual radiation quanta received during the sensitive time period, and a radiation category is assigned to each of the distinguished radiation quanta based on its corresponding interaction pattern.
    Type: Application
    Filed: May 23, 2011
    Publication date: January 12, 2012
    Applicant: CERN-European Organization for Nuclear Research
    Inventors: Erik Henricus M. Heijne, Stanislav Pospisil
  • Publication number: 20110297836
    Abstract: A method and an apparatus for measuring the dose, the dose rate and/or the composition of radiation is disclosed. In the method, a detector means is exposed to a radiation environment, the detector means comprising an array of radiation sensing detector elements. The detector means is switched in a sensitive state for the duration of a sensitive time period, and during said sensitive time period, an interaction pattern generated by individual radiation quanta interacting with one or more of the detector elements is recorded. The duration of the sensitive time period can be precisely adapted to the intensity of the radiation that has to be recorded. The interaction pattern is analyzed to distinguish individual radiation quanta received during the sensitive time period, and a radiation category is assigned to each of the distinguished radiation quanta based on its corresponding interaction pattern.
    Type: Application
    Filed: September 30, 2008
    Publication date: December 8, 2011
    Applicants: Czech Technical University of Prague, CERN-European Organization for Nuclear Research
    Inventors: Erik Henricus M. HEIJNE, Stanislav Pospisil
  • Publication number: 20090057562
    Abstract: A method and an apparatus for measuring the dose, the dose rate and/or the composition of radiation is disclosed. In the method, a detector means is exposed to a radiation environment, the detector means comprising an array of radiation sensing detector elements. The detector means is switched in a sensitive state for the duration of a sensitive time period, and during said sensitive time period, an interaction pattern generated by individual radiation quanta interacting with one or more of the detector elements is recorded. The duration of the sensitive time period can be precisely adapted to the intensity of the radiation that has to be recorded. The interaction pattern is analyzed to distinguish individual radiation quanta received during the sensitive time period, and a radiation category is assigned to each of the distinguished radiation quanta based on its corresponding interaction pattern.
    Type: Application
    Filed: September 30, 2008
    Publication date: March 5, 2009
    Applicants: CERN-European Organization for Nuclear Research, Czech Technical University of Prague
    Inventors: Erik Henricus M. HEIJNE, Stanislav Pospisil