Patents by Inventor Stanley Chungsing Hiew

Stanley Chungsing Hiew has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Spiroindolinones and therapeutic uses thereof
    Patent number: 11174267
    Abstract: Small molecules comprised of spiroindolinone analogues are provided. Some spiroindolinones are provided with a particular relative stereochemistry in which the indolone carbonyl and all three hydrogens are on the same face of the central pyrrolidine ring. A stereoselective method of synthesis is provided for making some of the spiroindolinones described above. Formulations and medicaments are also provided that are directed to the treatment of disease, such as, for example, fungal infections. Therapeutics are also provided containing a therapeutically effective dose of one or more small molecule compounds, present either as pharmaceutically effective salt or in pure form, including, but not limited to, formulations for oral, intravenous, or intramuscular administration.
    Type: Grant
    Filed: June 13, 2016
    Date of Patent: November 16, 2021
    Assignee: The Regents of the University of California
    Inventors: David Lee Van Vranken, Haoping Liu, Ilandari Dewage Udara Anulal Premachandra, Fuqiang Wang, Chengtian Shen, Kevin Andre Scott, Shelley Ren-An Lane, Aaron David Mood, Stanley Chungsing Hiew
  • Spiroindolinones and Therapeutic Uses Thereof
    Publication number: 20200140449
    Abstract: Small molecules comprised of spiroindolinone analogues are provided. Some spiroindolinones are provided with a particular relative stereochemistry in which the indolone carbonyl and all three hydrogens are on the same face of the central pyrrolidine ring. A stereoselective method of synthesis is provided for making some of the spiroindolinones described above. Formulations and medicaments are also provided that are directed to the treatment of disease, such as, for example, fungal infections. Therapeutics are also provided containing a therapeutically effective dose of one or more small molecule compounds, present either as pharmaceutically effective salt or in pure form, including, but not limited to, formulations for oral, intravenous, or intramuscular administration.
    Type: Application
    Filed: June 13, 2016
    Publication date: May 7, 2020
    Applicant: The Regents of the University of California
    Inventors: David Lee Van Vranken, Haoping Liu, IIandari Dewage Premachandra, Fuqiang Wang, Chengtian Shen, Kevin Andre Scott, Shelley Ren-An Lane, Aaron David Mood, Stanley Chungsing Hiew