Patents by Inventor Stanley Durrleman

Stanley Durrleman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for determining the temporal progression of a biological phenomenon and associated methods and devices
    Patent number: 10832089
    Abstract: Provided herein is a method for determining the temporal progression of a biological phenomenon which may affect a studied subject, the method including the steps of providing first data relative to biomarkers for the studied subject, the biomarkers being relative to the progression of the biological phenomenon, providing a numerical model, converting the first data into at least one point on the same Riemann manifold, and using a numerical model to determine a temporal progression for the biological phenomenon for the studied subject, the numerical model being a function in a Riemann manifold, the numerical model associating to values of biomarkers a temporal progression trajectory for the biological phenomenon and data relative to the dispersion of the progression trajectory for the biological phenomenon among a plurality of subjects, the numerical model being obtained by using a stochastic approximation in an expectation-maximization technique on data relative to biomarkers.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: November 10, 2020
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE, ECOLE POLYTECHNIQUE, INRIA INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET AN AUTOMATIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SORBONNE UNIVERSITÉ, ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
    Inventors: Stanley Durrleman, Jean-Baptiste Schiratti, Stéphanie Allassonniere, Olivier Colliot
  • A METHOD FOR DETERMINING THE TEMPORAL PROGRESSION OF A BIOLOGICAL PHENOMENON AND ASSOCIATED METHODS AND DEVICES
    Publication number: 20190138846
    Abstract: Provided herein is a method for determining the temporal progression of a biological phenomenon which may affect a studied subject, the method including the steps of providing first data relative to biomarkers for the studied subject, the biomarkers being relative to the progression of the biological phenomenon, providing a numerical model, converting the first data into at least one point on the same Riemann manifold, and using a numerical model to determine a temporal progression for the biological phenomenon for the studied subject, the numerical model being a function in a Riemann manifold, the numerical model associating to values of biomarkers a temporal progression trajectory for the biological phenomenon and data relative to the dispersion of the progression trajectory for the biological phenomenon among a plurality of subjects, the numerical model being obtained by using a stochastic approximation in an expectation-maximization technique on data relative to biomarkers.
    Type: Application
    Filed: May 11, 2016
    Publication date: May 9, 2019
    Inventors: Stanley Durrleman, Jean-Baptiste Schiratti, Stéphanie Allassonniere, Olivier Colliot
  • Methods and systems to produce continuous trajectories from discrete anatomical shapes
    Patent number: 9142042
    Abstract: A method of estimating changes in an anatomical structure over time. The method includes steps of obtaining a plurality of shapes of an anatomical structure from a plurality of points in time, wherein the plurality of shapes of the anatomical structure includes a baseline shape of the anatomical structure; continuously deforming the baseline shape of the anatomical structure using a growth model parameterized by acceleration; fitting the deformed baseline shape to at least one of the plurality of shapes of the anatomical structure; and using the deformed baseline shape to estimate at least one shape of the anatomical structure at a time corresponding to a time that is different than any of the plurality of points in time.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: September 22, 2015
    Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Guido Gerig, Stanley Durrleman, James Fishbaugh
  • METHODS AND SYSTEMS TO PRODUCE CONTINUOUS TRAJECTORIES FROM DISCRETE ANATOMICAL SHAPES
    Publication number: 20130188849
    Abstract: A method of estimating changes in an anatomical structure over time. The method includes steps of obtaining a plurality of shapes of an anatomical structure from a plurality of points in time, wherein the plurality of shapes of the anatomical structure includes a baseline shape of the anatomical structure; continuously deforming the baseline shape of the anatomical structure using a growth model parameterized by acceleration; fitting the deformed baseline shape to at least one of the plurality of shapes of the anatomical structure; and using the deformed baseline shape to estimate at least one shape of the anatomical structure at a time corresponding to a time that is different than any of the plurality of points in time.
    Type: Application
    Filed: September 13, 2012
    Publication date: July 25, 2013
    Inventors: Guido Gerig, Stanley Durrleman, James Fishbaugh