Patents by Inventor Stanley E. D'Souza

Stanley E. D'Souza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides and antibodies that inhibit integrin-ligand binding
    Patent number: 5262520
    Abstract: Polypeptides derived from the ligand-binding portion of an Integrin alpha subunit are disclosed as are their use for modulation of Integrin ligand binding. Anti-peptide antibodies, hybridomas secreting the antibodies, as well as methods of making and using such antibodies and recombinant DNA molecules coding for the polypeptides are also described. The polypeptides and antibodies to the polypeptides are effective inhibitors of fibrinogen binding to platelets.
    Type: Grant
    Filed: November 29, 1990
    Date of Patent: November 16, 1993
    Assignee: The Scripps Research Institute
    Inventors: Edward F. Plow, Stanley E. D'Souza, Mark H. Ginsberg
  • Peptides and antibodies that inhibit integrin-ligand binding
    Patent number: 5204445
    Abstract: Polypeptides which are derived from the Arg-Gly-Asp (RGD) binding portion of an Integrin beta subunit are disclosed as are their use for modulation of Integrin ligand binding. Anti-peptide antibodies, hybridomas secreting these antibodies, as well as methods of making and using such antibodies, and recombinant DNA molecules that define the structural gene coding for the polypeptides are also contemplated as within the scope of the present invention.
    Type: Grant
    Filed: October 2, 1989
    Date of Patent: April 20, 1993
    Assignee: The Scripps Research Institute
    Inventors: Edward F. Plow, Stanley E. D'Souza, Mark H. Ginsberg
  • Peptides and antibodies that inhibit integrin-ligand binding
    Patent number: 5196511
    Abstract: Polypeptides which are derived from the ligand-binding portion of an Integrin alpha subunit are disclosed as are their use for modulation of Integrin ligand binding. Anti-peptide antibodies, hybridomas secreting these antibodies, as well as methods of making and using such antibodies, and recombinant DNA molecules that define the structural gene coding for the polypeptides are also contemplated as within the scope of the present invention.
    Type: Grant
    Filed: December 1, 1989
    Date of Patent: March 23, 1993
    Assignee: The Scripps Research Institute
    Inventors: Edward F. Plow, Stanley E. D'Souza, Mark H. Ginsberg
  • Peptides and antibodies that inhibit integrin-ligand binding
    Patent number: 5149780
    Abstract: Polypeptides which are derived from the Arg-Gly-Asp (RGD) binding portion of an Integrin beta subunit are disclosed as are their use for modulation of Integrin ligand binding. Anti-antibody peptides, hybridomas secreting these antibodies, as well as methods of making any using such antibodies, and recombinant DNA molecules that define the structural gene coding for the polypeptides are also contemplated within the scope of the present invention.
    Type: Grant
    Filed: October 3, 1988
    Date of Patent: September 22, 1992
    Assignee: The Scripps Research Institute
    Inventors: Edward F. Plow, Stanley E. D'Souza, Mark H. Ginsberg