Patents by Inventor Stanley F. Wolf

Stanley F. Wolf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ASSAYS AND METHODS FOR EVALUATING MULTIMERIC COMPLEXES
    Publication number: 20090156421
    Abstract: Assays, e.g., homogenous assays, and methods for identifying, quantifying and/or monitoring the formation and/or stability of a multimeric complex, e.g., a ternary complex are disclosed. The methods and assays of the invention can be used to identify and/or evaluate agents (e.g., proteins, peptides, antibody molecules, and small and large molecules) that interfere with and/or inhibit the formation of a multimeric complex (e.g., a ternary complex) or that disrupt a previously formed complex.
    Type: Application
    Filed: November 6, 2008
    Publication date: June 18, 2009
    Applicant: WYETH
    Inventors: Xiaoke Yang, Lori J. Fitz, Julie M. Lee, Jonathan Brooks, Stanley F. Wolf
  • Natural killer stimulatory factor
    Patent number: 7122633
    Abstract: This application relates to antibodies reactive with a novel homogenous human cytokine, Natural Killer Stimulator Factor (NKSF), having the ability to induce the production of gamma interferon in vitro in human peripheral blood lymphocytes, and a pharmaceutical preparation containing such antibodies.
    Type: Grant
    Filed: February 5, 2003
    Date of Patent: October 17, 2006
    Assignees: The Wistar Institute, Wyeth
    Inventors: Giorgio Trinchieri, Bice Perussia, Stanley F. Wolf, Steven C. Clark, Gordon G. Wong, Rodney Hewick, Michiko Kobayashi
  • Enhancing immune responses with B7-1 or B7-2 in the absence of a crosslinking agent
    Patent number: 7011833
    Abstract: Methods of enhancing immune responses in which soluble forms of costimulatory molecules, e.g., B7 molecules, are administered to augment immune responses to antigens, e.g., to tumor cells and infectious agents are provided. The subject methods are useful for both prophylactic and therapeutic immunization of subjects.
    Type: Grant
    Filed: May 5, 2000
    Date of Patent: March 14, 2006
    Assignee: Genetics Institute, Inc.
    Inventors: Knut Sturmhoefel, Stanley F. Wolf, Margot O'Toole
  • Antibodies to natural killer stimulatory factor
    Publication number: 20040044186
    Abstract: This application relates to antibodies reactive with a novel homogenous human cytokine, Natural Killer Stimulator Factor (NKSF), having the ability to induce the production of gamma interferon in vitro in human peripheral blood lymphocytes, and a pharmaceutical preparation containing such antibodies.
    Type: Application
    Filed: February 5, 2003
    Publication date: March 4, 2004
    Applicant: Wyeth and The Wistar Institute
    Inventors: Giorgio Trinchieri, Bice Perussia, Stanley F. Wolf, Steven C. Clark, Gordon G. Wong, Rodney Hewick, Michiko Kobayashi
  • Antibodies to natural killer stimulatory factor
    Patent number: 5811523
    Abstract: A novel homogeneous human cytokine, Natural Killer Stimulatory Factor, having the ability to induce the production of gamma interferon in vitro in human peripheral blood lymphocytes, and a pharmaceutical preparation containing it.
    Type: Grant
    Filed: October 22, 1997
    Date of Patent: September 22, 1998
    Inventors: Giorgio Trinchieri, Bice Perussia, Steven C. Clark, Gordon G. Wong, Rodney Hewick, Michiko Kobayashi, Stanley F. Wolf
  • Use of interleukin-12 to prevent graft versus host disease
    Patent number: 5756085
    Abstract: The use of interleukin-12 to prevent, to ameliorate, and to treat graft-versus-host disease in a mammal in need of such treatment is disclosed. In other embodiments, graft-vs. leukemia effects are maintained or promoted.
    Type: Grant
    Filed: April 30, 1996
    Date of Patent: May 26, 1998
    Assignees: Genetics Institute, Inc., The General Hospital Corporation
    Inventors: Megan Sykes, Stanley F. Wolf
  • Methods of inducing gamma interferon and stimulating blood cell populations using natural killer stimulatory factor
    Patent number: 5648072
    Abstract: Methods of inducing gamma interferon production and stimulating lymphocyte populations using Natural Killer Stimulatory Factor (NKSF) are disclosed.
    Type: Grant
    Filed: March 13, 1995
    Date of Patent: July 15, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: Giorgio Trinchieri, Bice Perussia, Steven C. Clark, Michiko Kobayashi, Gordon G. Wong, Rodney Hewick, Stanley F. Wolf
  • Natural killer cell stimulatory factor
    Patent number: 5648467
    Abstract: A novel homogeneous human cytokine, Natural Killer Stimulatory Factor, having the ability to induce the production of gamma interferon in vitro in human peripheral blood lymphocytes, and a pharmaceutical preparation containing it.
    Type: Grant
    Filed: March 13, 1995
    Date of Patent: July 15, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: Giorgio Trinchieri, Bice Perussia, Steven C. Clark, Gordon G. Wong, Rodney Hewick, Michiko Kobayashi, Stanley F. Wolf
  • Use of interleukin-12 to prevent graft versus host disease
    Patent number: 5573764
    Abstract: The use of interleukin-12 to prevent, to ameliorate, and to treat graft-versus-host disease in a mammal in need of such treatment is disclosed.
    Type: Grant
    Filed: January 21, 1994
    Date of Patent: November 12, 1996
    Assignees: Genetics Institute, Inc., The General Hospital Corporation
    Inventors: Megan Sykes, Stanley F. Wolf
  • Methods of treating infection using natural killer stimulatory factor
    Patent number: 5569454
    Abstract: Methods of treating an infection using Natural Killer Stimulatory Factor (NKSF) are disclosed.
    Type: Grant
    Filed: March 13, 1995
    Date of Patent: October 29, 1996
    Assignee: Genetics Institute, Inc.
    Inventors: Giorgio Trinchieri, Bice Perussia, Steven C. Clark, Gordon G. Wong, Rodney Hewick, Michiko Kobayashi, Stanley F. Wolf