Abstract: A tubing occlusion clip comprising a first wall portion, first and second arms joined to spaced regions of the first wall portion and a closing wall portion joined to the first arm and extendible to the second arm such that the arms cooperate with the wall portions to form a closed loop. The wall portions have openings, and a tube is coupled to the first wall portion and extends across the closed loop and through the opening of the closing wall portion. First and second clamping members are carried by the first and second arms, respectively, and they are adapted to have the tube extend therebetween. The arms are relatively movable toward each other to a clamping position in which the tube is clamped between the clamping members and relatively movable away from each other to a releasing position. Interlocking members are provided on the closing wall portion and the second arm for positively locking the closed loop against opening when the arms are in the releasing position.