Patents by Inventor Stanley Kahler

Stanley Kahler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biologically active taxane analogs and methods of treatment
    Publication number: 20110028539
    Abstract: The present application relates to new taxane analogs, pharmaceutical compositions comprising such analogs and methods of treating cancer comprising such compositions. The compounds according to the present application have the general formula: wherein R1 and R2 are each selected from H, alkyl, alkenyl or aryl; R3 is hydroxyl or OP1; R4 is OH or R7COO; R7 is alkyl, alkenyl or aryl, R8 and R9 are each independently selected from H, alkyl or alkenyl. The compounds of the present application may particularly be 9,10-?,?-OH taxane analogs that are formed by a process starting with a standard taxane as the starting compound.
    Type: Application
    Filed: April 9, 2010
    Publication date: February 3, 2011
    Applicant: Tapestry Pharmaceuticals, Inc.
    Inventors: James D. McChesney, Rodger Lamb, Stanley Kahler
  • Biologically active taxane analogs and methods of treatment
    Publication number: 20110009480
    Abstract: The present application relates to new taxane analogs, pharmaceutical compositions comprising such analogs and methods of treating cancer comprising such compositions. The compounds according to the present application have the general formula: wherein R1 and R2 are each selected from H, alkyl, alkenyl or aryl; R3 is hydroxyl or OP1; R4 is OH or R7COO; R7 is alkyl, alkenyl or aryl, R8 and R9 are each independently selected from H, alkyl or alkenyl. The compounds of the present application may particularly be 9,10-?,?-OH taxane analogs that are formed by a process starting with a standard taxane as the starting compound.
    Type: Application
    Filed: April 9, 2010
    Publication date: January 13, 2011
    Applicant: Tapestry Pharmaceuticals, Inc.
    Inventors: James D. McChesney, Rodger Lamb, Stanley Kahler
  • Biologically active taxane analogs and methods of treatment
    Publication number: 20080269319
    Abstract: The present application relates to new taxane analogs, pharmaceutical compositions comprising such analogs and methods of treating cancer comprising such compositions. The compounds according to the present application have the general formula: wherein R1 and R2 are each selected from H, alkyl, alkenyl or aryl; R3 is hydroxyl or OP1; R4 is OH or R7COO; R7 is alkyl, alkenyl or aryl, R8 and R9 are each independently selected from H, alkyl or alkenyl. The compounds of the present application may particularly be 9,10-?,?-OH taxane analogs that are formed by a process starting with a standard taxane as the starting compound.
    Type: Application
    Filed: June 26, 2008
    Publication date: October 30, 2008
    Applicant: Tapestry Pharmaceuticals, Inc.
    Inventors: James D. McChesney, Rodger Lamb, Stanley Kahler
  • Biologically active taxane analogs and methods of treatment
    Publication number: 20080207744
    Abstract: The present application relates to new taxane analogs, pharmaceutical compositions comprising such analogs and methods of treating cancer comprising such compositions. The compounds according to the present application have the general formula: wherein R1 and R2 are each selected from H, alkyl, alkenyl or aryl; R3 is hydroxyl or OP1; R4 is OH or R7COO; R7 is alkyl, alkenyl or aryl, R8 and R9 are each independently selected from H, alkyl or alkenyl. The compounds of the present application may particularly be 9,10-?,?-OH taxane analogs that are formed by a process starting with a standard taxane as the starting compound.
    Type: Application
    Filed: May 3, 2007
    Publication date: August 28, 2008
    Inventors: James D. McChesney, Rodger Lamb, Stanley Kahler
  • Biologically Active Taxane Analogs and Methods of Treatment
    Publication number: 20080207743
    Abstract: The present application relates to new taxane analogs, pharmaceutical compositions comprising such analogs and methods of treating cancer comprising such compositions. The compounds according to the present application have the general formula: wherein R1 and R2 are each selected from H, alkyl, alkenyl or aryl; R3 is hydroxyl or OP1; R4 is OH or R7COO; R7 is alkyl, alkenyl or aryl, R8 and R9 are each independently selected from H, alkyl or alkenyl. The compounds of the present application may particularly be 9,10-?,?-OH taxane analogs that are formed by a process starting with a standard taxane as the starting compound.
    Type: Application
    Filed: February 28, 2007
    Publication date: August 28, 2008
    Inventors: Rodger Lamb, Stanley Kahler