Abstract: Methods, systems, and devices for defining an action node series at a database system are described. In some examples, the workflow may include one or more nodes are associated with an action. When executed, the workflow may produce an outcome based on the occurrence of an event or parameter associated with the one or more nodes. In some examples, the workflow may include one or more branch nodes. A branch node may include logic such that, when the workflow is executed, the logic selects a particular workflow path that includes its own specific nodes. The path may be selected based on the occurrence of an event or a value of one or more parameters. Thus, when a workflow including one or more branch nodes is executed, the outcome of the workflow may be based on the occurrence of the event or the value of the parameter.

Abstract: Methods, systems, and devices for defining an action node series at a database system are described. In some examples, the workflow may include one or more nodes are associated with an action. When executed, the workflow may produce an outcome based on the occurrence of an event or parameter associated with the one or more nodes. In some examples, the workflow may include one or more branch nodes. A branch node may include logic such that, when the workflow is executed, the logic selects a particular workflow path that includes its own specific nodes. The path may be selected based on the occurrence of an event or a value of one or more parameters. Thus, when a workflow including one or more branch nodes is executed, the outcome of the workflow may be based on the occurrence of the event or the value of the parameter.

Abstract: The present invention provides replication competent polynucleotides that include a coding sequence encoding a hepatitis C virus polyprotein having adaptive mutations. The invention also includes methods for malting replication competent polynucleotides, identifying a compound that inhibits replication of a replication competent polynucleotide, selecting a replication competent polynucleotide, and detecting a replication competent polynucleotide.

Abstract: The present invention relates generally to the fields of biochemistry, molecular biology, and virology. More particularly, it relates to the identification of GB virus B (GBV-B)/HCV chimeras. The invention involves nucleic acid constructs and compositions encoding GBV-B/HCV chimera, including at least part of a 5? NTR derived from a HCV 5? NTR. This construct, and chimeric versions of it, may be employed to study GBV-B and related hepatitis family members, such as hepatitis C virus. The invention thus includes methods of preparing GBV-B/HCV chimeric sequences, constructs, and viruses, as well as methods of employing these compositions.

Abstract: The present invention relates generally to the fields of biochemistry, molecular biology, and virology. More particularly, it relates to the production and use of GB virus B (GBV-B)/HCV chimeras. The invention involves nucleic acid constructs and compositions encoding GBV-B/HCV chimera. The chimeric viruses may be employed to study GBV-B and related hepatitis family members, such as hepatitis C virus. The invention thus includes methods of preparing GBV-B/HCV chimeric sequences, constructs, and viruses, as well as methods of employing these compositions.

Abstract: The present invention provides a replication competent hepatitis C virus that includes a heterologous polynucleotide. The invention also includes methods for modifying a hepatitis C virus polynucleotide, selecting a replication competent hepatitis C virus polynucleotide, detecting a replication competent hepatitis C virus polynucleotide, and identifying a compound that inhibits replication of a hepatitis C virus polynucleotide.