Abstract: A method of affecting metabolic function is presented which utilizes a conductive coating, film, or covering on a body tissue to distribute electrical charge, either passively or in conjunction with applied electrical energy.

Abstract: A method of affecting metabolic function is presented which utilizes a conductive coating, film, or covering on a body tissue to distribute electrical charge, either passively or in conjunction with applied electrical energy.

Abstract: A reusable endoscopic surgical instrument includes a handle assembly attached to a slender shaft assembly. The shaft assembly includes inner and outer shafts, with the inner shaft being rotatable by operation of the handle assembly to rotate a surgical tool operably connected to the distal end of a pushrod disposed within the inner shaft. The handle assembly includes first actuating mechanism for actuating the pushrod to operate the surgical tool and a second actuating mechanism for rotating the inner shaft. The outer shaft is axially slidable with respect to the inner shaft to cover a flush port system in the handle assembly for cleaning and improved sterilizability of the instrument.

Abstract: A method and apparatus is disclosed for supporting and handling blot membranes during the course of blotting, analysis and storage.

Abstract: A method is disclosed for molding thin gel slabs horizontally having deep, large volume sample wells molded integrally and in communication with the thin gel slab. The disclosure includes a method for molding at least two contiguous thin gel slabs horizontally.

Abstract: A rapid and effective method and apparatus or blotting is provided whereby a relatively thin gel slab containing electrophoresed, electrostatically charged material is transferred to a porous membrane of opposite charge by means of simple electrostatic attraction free of any external influence or inducement.

Abstract: A method and apparatus is disclosed for supporting and handling blot membranes during the course of blotting, analysis and storage.

Abstract: A method and apparatus is disclosed for molding thin gel slabs horizontally having deep, large volume sample wells molded integrally and in communication with the thin gel slab. The disclosure includes a method and apparatus for molding at least two contiguous thin gel slabs horizontally.

Abstract: The apparatus and process of the present invention resolves sample species in an electrolyte solution containing two or more types of ions, wherein the sample species to be resolved will move in response to fluid flow of the electrolyte and a non-linear voltage gradient such that the non-linear voltage gradient serves to counteract forces of diffusion as the sample travels along the electrophoresis chamber good resolution is obtained in species of widely divergent electrophoretic mobility.

Abstract: An isoelectric focusing technique and apparatus is described in which a steady-state pH gradient is established by the use of a series of parallel electrodes which border the focusing chamber and which may be clamped at varying voltages independently of one another. By maintaining appropriate voltages along with length of the chamber, the ionic species present in the buffer solution will be concentrated at either the anode or cathode end, depending on their charge, and the charge imbalance resulting from this concentration effect will cause the dissociation of water with the concommitant establishment of a pH gradient. By varying the intensity and shape of the voltage gradient, a wide range of pH gradients, and median values for these gradients, may be selected. Further, the gradient may be altered at will during the isoelectric focusing run without disturbing the components being resolved, allowing maximum resolution of a number of components from one run.