Abstract: The present invention concerns methods of diagnosing and/or prognostication of non-alcoholic fatty liver disease (NAFLD) or alcohol-related fatty liver disease (ARLD) in a subject, wherein said methods comprise detecting somatic mutations in DNA, RNA and/or protein that confer a selective advantage on one or more liver cells of the subject. The present invention also provides methods for identifying subjects suffering from NAFLD or ARLD who would benefit from treatment with a therapeutic agent and/or identifying subjects suffering from NAFLD or ARLD who would benefit from increased disease monitoring. The present invention also provides therapeutic agents that find utility in the treatment of NAFLD or ARLD.

Abstract: There is described herein an assay comprising, for each of DNMT3B, ZBTB46, NYNRIN, ARHGAP22, LAPTM4B, MMRN1, DPYSL3, KIAA0125, CDK6, CPXM1, SOCS2, SMIM24, EMP1, NGFRAP1, CD34, AKR1C3, GPR56, a pair of probes complementary and hybridizable thereto on an array, optionally with a set of reference genes.

Abstract: There is described herein a method of prognosing or classifying a subject with acute myeloid leukemia (AML) comprising: (a) determining the expression level of at least 3 genes in a test sample from the subject selected from the group consisting of DNMT3B, ZBTB46, NYNRIN, ARHGAP22, LAPTM4B, MMRN1, DPYSL3, KIAAQ125. CDK6, CPXM1, SOCS2, SMIM24, EMP1, NGFRAP1, CD34, AKR1C3, GPR56; and (b) comparing expression of the at least 3 genes in the test sample with reference expression levels of the at least 3 genes from control samples from a cohort of patients; wherein a difference or similarity in the expression of the at least 3 genes in the test sample and the reference expression levels is used to prognose or classify the subject with AML into a low risk group or a high risk group for worse survival.

Abstract: There is described herein a method of prognosing or classifying a subject with acute myeloid leukemia (AML) comprising: (a) determining the expression level of at least 3 genes in a test sample from the subject selected from the group consisting of DNMT3B, ZBTB46, NYNRIN, ARHGAP22, LAPTM4B, MMRN1, DPYSL3, KIAAQ125. CDK6, CPXM1, SOCS2, SMIM24, EMP1, NGFRAP1, CD34, AKR1C3, GPR56; and (b) comparing expression of the at least 3 genes in the test sample with reference expression levels of the at least 3 genes from control samples from a cohort of patients; wherein a difference or similarity in the expression of the at least 3 genes in the test sample and the reference expression levels is used to prognose or classify the subject with AML into a low risk group or a high risk group for worse survival.

Abstract: Multiband antenna decoupling networks and systems including multiband antenna decoupling networks are provided herein. A multiband decoupling network is connected to two or more closely spaced antennas. The multiband decoupling network includes lumped components and is reconfigurable to decouple the two or more antennas at a plurality of distinct communication frequency bands. The multiband decoupling network may include tunable lumped components and be reconfigurable through tuning the tunable lumped components. A pi network may be used for the multiband decoupling network. At least one separate impedance-matching network may also be used to match the input impedance of the multiband decoupling network to the output impedance of transmission lines leading to the multiband decoupling network.

Abstract: Mobile communication devices include multi-band antennas that use an internal conductor and a perimeter conductor to define antenna sections that are coupled together based on an RF wavelength of interest. The antenna sections can be selected or deselected by shunting to ground using a passive filter device or an active RF switch. In other examples, filters or switches are configured to couple an internal conductor and a portion of a perimeter conductor together to provide an effective antenna length associated with a selected frequency.

Abstract: This is directed to a personalized avatar providing a true representation of the user's body, such that the avatar provides a substantially accurate graphical representation of the user's body. The avatar can be defined using any suitable approach, including by providing measurements of the user's body or extracting measurements from photographs of the user. The user can direct an electronic device to apply selected articles of clothing, accessories, or other items to the user's avatar to preview the appearance of the items on the user. In some embodiments, an electronic device can recommend different clothing items or other objects based on the user's body type.

Abstract: Multiband antenna decoupling networks and systems including multiband antenna decoupling networks are provided herein. A multiband decoupling network is connected to two or more closely spaced antennas. The multiband decoupling network includes lumped components and is reconfigurable to decouple the two or more antennas at a plurality of distinct communication frequency bands. The multiband decoupling network may include tunable lumped components and be reconfigurable through tuning the tunable lumped components. A pi network may be used for the multiband decoupling network. At least one separate impedance-matching network may also be used to match the input impedance of the multiband decoupling network to the output impedance of transmission lines leading to the multiband decoupling network.

Abstract: Improved techniques for interaction between a host computer (e.g., personal computer) and a media player are disclosed. According to one embodiment, interaction between a host device (e.g., host computer) and a media player can be performed over a wireless channel. The interaction over the wireless channel can be used to automatically synchronize media contents stored on the media player with media contents stored on the host device. According to another embodiment, interaction between a host device and a media player, such as automatic synchronization of media contents stored on a media player with media contents stored on a host device, can be restricted. In still another embodiment, synchronization can be automatically performed when the media player is placed in a docking station that supports wireless communications.

Abstract: Improved techniques for interaction between a host computer (e.g., personal computer) and a media player are disclosed. According to one embodiment, interaction between a host device (e.g., host computer) and a media player can be performed over a wireless channel. The interaction over the wireless channel can be used to automatically synchronize media contents stored on the media player with media contents stored on the host device. According to another embodiment, interaction between a host device and a media player, such as automatic synchronization of media contents stored on a media player with media contents stored on a host device, can be restricted. In still another embodiment, synchronization can be automatically performed when the media player is placed in a docking station that supports wireless communications.

Abstract: Improved techniques for interaction between a host computer (e.g., personal computer) and a media player are disclosed. According to one embodiment, interaction between a host device (e.g., host computer) and a media player can be performed over a wireless channel. The interaction over the wireless channel can be used to automatically synchronize media contents stored on the media player with media contents stored on the host device. According to another embodiment, interaction between a host device and a media player, such as automatic synchronization of media contents stored on a media player with media contents stored on a host device, can be restricted. In still another embodiment, synchronization can be automatically performed when the media player is placed in a docking station that supports wireless communications.

Abstract: This is directed to a personalized avatar providing a true representation of the user's body, such that the avatar provides a substantially accurate graphical representation of the user's body. The avatar can be defined using any suitable approach, including by providing measurements of the user's body or extracting measurements from photographs of the user. The user can direct an electronic device to apply selected articles of clothing, accessories, or other items to the user's avatar to preview the appearance of the items on the user. In some embodiments, an electronic device can recommend different clothing items or other objects based on the user's body type.

Abstract: This is directed to a system and method for providing social networking services using a portable electronic device. In some embodiments, a user may identify one or more articles of interest and transmit identifying information for the articles to mobile or other devices of the user's friends. The user's friends can review the identified articles, and provide comments for the user. For example, the user's friends can give a thumbs up/down, a star rating, a comment (e.g., text, audio or video), or any other type of comment. In some embodiments, the user can request the assistance of a salesperson using the social networking application device, for example to request recommended articles based on a particular event or need. In some embodiments, the social networking application can provide information to or from a kiosk.

Abstract: A system and method for the managed distribution of digital media. A capture station captures media resources by converting the media resources into digital form. Once captured in digital form, the digital media is communicated to a formatting server. The formatting server encodes and encrypts the digital media into a desired form for distribution by the system. The digital media is stored in a master media server. Users are allowed to access the digital media using a media presentation client. A user can request access to digital media stored on the master media server. The system allows various access restrictions to be defined to restrict access to the digital media. If a user is authorized to access a piece of digital media, the digital media may be delivered to the media presentation client by the master media server.

Abstract: The present invention pertains to improved feedback mechanisms for touch pads. One aspect relates to devices capable of illuminating the touch sensitive surface of the touch pad. Another aspect relates to methods for providing visual feedback at the touch pad.

Abstract: The present invention pertains to improved feedback mechanisms for touch pads. One aspect relates to devices capable of illuminating the touch sensitive surface of the touch pad. Another aspect relates to methods for providing visual feedback at the touch pad.

Abstract: Techniques for securing and controlling access to digital data are disclosed. A security-code is generated based on a plurality of input received from an input device which does not have to be a keyboard (e.g., joy-stick, sensor, touch-screen), but can detect movement input by a user. The movement can, for example, be received as rotational movement to emulate a mechanical combination lock which is familiar and easy to use. Digital data is secured by a security code generated in response to movement (e.g., rotational movement) which can be conveniently entered by users. Users can conveniently reenter the security-code by input movement in order to access secured digital data.

Abstract: Improved techniques for interaction between a host computer (e.g., personal computer) and a media player are disclosed. According to one embodiment, interaction between a host device (e.g., host computer) and a media player can be performed over a wireless channel. The interaction over the wireless channel can be used to automatically synchronize media contents stored on the media player with media contents stored on the host device. According to another embodiment, interaction between a host device and a media player, such as automatic synchronization of media contents stored on a media player with media contents stored on a host device, can be restricted. In still another embodiment, synchronization can be automatically performed when the media player is placed in a docking station that supports wireless communications.