Patents by Inventor Stanley Oyaghire

Stanley Oyaghire has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HYDROXYMETHYL-MODIFIED GAMMA-PNA COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20220372474
    Abstract: Peptide nucleic acid (PNA) oligomers having one or more hydroxymethyl ?-substitutions, also referred to herein as “ser?PNA”, are provided. The hydroxymethyl ?-substitution preserves and amplifies the helical preorganization that is valuable for DNA duplex invasion by the oligomer. ser?PNA-containing triplex-forming molecules can be used in combination with a donor DNA fragment to facilitate genome modification in vitro and in vivo.
    Type: Application
    Filed: June 22, 2020
    Publication date: November 24, 2022
    Inventors: Elias Quijano, Stanley Oyaghire, W. Mark Saltzman, Peter Glazer