Patents by Inventor Stanley Tyms

Stanley Tyms has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiviral compounds
    Patent number: 7601735
    Abstract: Use of certain castanospermine esters in the treatment of diseases caused by flaviviruses, in particular in the treatment of disease caused by the hepatitis C virus (HCV) and compositions containing said esters in combination with adjunctive therapeutic agents.
    Type: Grant
    Filed: May 2, 2002
    Date of Patent: October 13, 2009
    Assignee: Virogen Ltd.
    Inventors: Albert Stanley Tyms, Debra Lynn Taylor
  • Benzodiazepine derivatives and pharmaceutical compositions containing them
    Patent number: 7582624
    Abstract: Benzodiazepine derivative of formula (I), and pharmaceutically acceptable salts thereof, are found to be active against RSV.
    Type: Grant
    Filed: September 22, 2003
    Date of Patent: September 1, 2009
    Assignee: Arrow Therapeutics Limited
    Inventors: Malcolm Carter, Philip Chambers, Verity Dowdell, Elisa Ann Henderson, Richard David Kelsey, Debra Taylor, Stanley Tyms, Lara Wilson
  • Antiviral compounds
    Publication number: 20040147549
    Abstract: Use of certain castanospermine esters in the treatment of diseases caused by flaviviruses, in particular in the tretment of disease caused by the hepatitis C virus (HCV) and compositions containing said esters in combination with adjunctive therapeutic agents.
    Type: Application
    Filed: March 9, 2004
    Publication date: July 29, 2004
    Inventors: Albert Stanley Tyms, Debra Lynn Taylor
  • Combinations of retroviral inhibitors
    Patent number: 5939430
    Abstract: The combination of compounds of formula I and II can be used for the treatment of retroviraI infections. The combination can be used to treat AIDS and ARC and other diseases caused by the retrovirus HTV or other related viruses.
    Type: Grant
    Filed: July 20, 1995
    Date of Patent: August 17, 1999
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: A. Stanley Tyms, Debra L. Taylor
  • Sulfonic stilbene compounds in the treatment of viral diseases
    Patent number: 5932614
    Abstract: Sulfonic acid stilbenes block the infection of cells by HIV and these compounds can be used to prevent viral infection.
    Type: Grant
    Filed: November 5, 1996
    Date of Patent: August 3, 1999
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Alan D. Cardin, A. Stanley Tyms
  • Sulfonic stilbene derivatives in the treatment of viral diseases
    Patent number: 5672625
    Abstract: Sulfonic acid stilbenes block the infection of cells by HSV and CMV and these compounds can be used to treat viral infection.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: September 30, 1997
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Alan D. Cardin, A. Stanley Tyms
  • Sulfonic stilbene derivatives in the treatment of viral disease
    Patent number: 5494932
    Abstract: Sulfonic acid stilbenes block the infection of cells by HSV, and CMV and these compounds can be used to treat viral infection.
    Type: Grant
    Filed: May 25, 1994
    Date of Patent: February 27, 1996
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Alan D. Cardin, A. Stanley Tyms
  • Anti-herpes castanospermine esters
    Patent number: 5385911
    Abstract: Certain Castanospermine ester derivatives of the formula: ##STR1## wherein R, R.sub.1 and R.sub.2 are each independently hydrogen, C.sub.1-14 alkanoyl, C.sub.1-14 alkenoyl, cyclohexanecarbonyl, C.sub.1-8 alkoxyacetyl, ##STR2## naphthalenecarbonyl optionally substituted by methyl or halogen; phenyl (C.sub.2-6 alkanoyl) wherein the phenyl is optionally substituted by methyl or halogen; cinnamoyl; pyridinecarbonyl optionally substituted by methyl or halogen; dihydropyridine carbonyl optionally substituted by C.sub.1 -C.sub.10 alkyl; thiophenecarbonyl optionally substituted by methyl or halogen; or furancarbonyl optionally substituted by methyl or halogen; Y is hydrogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, halogen, trifluoromethyl, C.sub.1-4 alkylsulfonyl, C.sub.1-4 alkylmercapto, cyano or dimethylamino; Y' is hydrogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, halogen or it is combined with Y to give 3,4-methylenedioxy; Y" is hydrogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy or halogen; with R, R.sub.1 and R.sub.
    Type: Grant
    Filed: April 1, 1993
    Date of Patent: January 31, 1995
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Sai P. Sunkara, Paul S. Liu, A. Stanley Tyms, Debra L. Taylor
  • Method of treating herpesviruses
    Patent number: 4957926
    Abstract: A method is disclosed for the treatment of herpesvirus infections comprising treating the infected host with an effective amount of an N-alkyl derivative of deoxynojirimycin in which the alkyl group contains from one to about six carbon atoms, and preferably is butyl.
    Type: Grant
    Filed: December 22, 1988
    Date of Patent: September 18, 1990
    Assignee: Monsanto Company
    Inventors: Gary S. Jacob, A. Stanley Tyms, Thomas W. Rademacher, Raymond A. Dwek