Abstract: A bio-hazardous waste processor and optional encasement is described that uses a coolant such as liquid nitrogen to make the waste brittle in the hopper before crushing, keep the waste brittle in the down chute after crushing and also during shredding in the demolition chamber. After shredding, a fog of sterilant is used to disinfect the waste. The apparatus comprises an input hopper with a crushing wheel and dead plate towards its base to reduce the size of large particles, and a down chute which leads the crushed waste from the crushing wheel to a demolition chamber. In the demolition chamber, shredding is implemented by: one or more hammers and one or more commercially available off-the-shelf saw blades, the hammer(s) and saw blade(s) rotating in the same or opposite directions; or, one or more commercially available off-the-shelf dado saw blades, adjacent dados rotating in opposite directions.