Patents by Inventor Stanley Vickers

Stanley Vickers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glucoronide adduct as gaba ligand
    Publication number: 20040259818
    Abstract: The quaternary ammonium N-glucuronide adduct of 7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-yl-methoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine is cleavable by glucuronidase enzymes in the body and can thereby act as a prodrug of a therapeutic agent which is a selective ligand for GABAA receptors, in particular having high affinity for the &agr;2 and/or &agr;3 subunit thereof, and is accordingly of benefit in the treatment and/or prevention of disorders of the central nervous system, including anxiety and convulsions.
    Type: Application
    Filed: July 26, 2004
    Publication date: December 23, 2004
    Inventors: Byron Halevy, Matthew Paul, Donghui Cui, Stacey Lynn Polsky, A. David Rodrigues, Jose Miguel Vega, Stanley Vickers
  • HMG-COA reductase inhibitor metabolites
    Patent number: 5385932
    Abstract: This invention relates to compounds of formulae I and II ##STR1## which are metabolites of tetrahydrosimvastatin and 5-hydroxy-tetrahydrosimvastatin and which are HMG--CoA reductase inhibitors.
    Type: Grant
    Filed: February 18, 1992
    Date of Patent: January 31, 1995
    Assignee: Merck & Co., Inc.
    Inventor: Stanley Vickers
  • HMG-CoA reductase inhibitor metabolites
    Patent number: 5112857
    Abstract: This invention relates to compounds of formulae I and II ##STR1## which are metabolites of tetrahydrosimvastatin and 5-hydroxy-tetrahydrosimvastatin and which are HMG-CoA reductase inhibitors.
    Type: Grant
    Filed: September 4, 1990
    Date of Patent: May 12, 1992
    Assignee: Merck & Co., Inc.
    Inventor: Stanley Vickers
  • .alpha.-Methyldopa-L-ascorbic acid compositions
    Patent number: 4434177
    Abstract: The application discloses a pharmaceutical composition for treating hypertension containing (A) L-.alpha.-methyl-3,4-dihydroxyphenylalanine and (B) salicylamide, phenylglyoxal or L-ascorbic acid.
    Type: Grant
    Filed: October 28, 1981
    Date of Patent: February 28, 1984
    Assignee: Merck & Co., Inc.
    Inventor: Stanley Vickers
  • 2-Substituted propoxy-3-cyano-5-hydroxypyridines and use as antihypertensives
    Patent number: 4374140
    Abstract: The present application discloses certain 2-substituted propoxy-3-cyano-5-hydroxypyridines. The compounds have pharmaceutical activity e.g. as antihypertensives.
    Type: Grant
    Filed: February 10, 1981
    Date of Patent: February 15, 1983
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Gerald S. Ponticello, Stanley Vickers, Alfred Steuerwald
  • .alpha.-methyldopa compositions
    Patent number: 4321264
    Abstract: The application discloses a pharmaceutical composition for treating hypertension containing (A) L-.alpha.-methyl-3,4-dihydroxyphenylalanine and (B) salicylamide, phenylglyoxal or L-ascorbic acid.
    Type: Grant
    Filed: April 14, 1980
    Date of Patent: March 23, 1982
    Assignee: Merck & Co., Inc.
    Inventor: Stanley Vickers