Patents by Inventor Stanton J. Rowe
Stanton J. Rowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12156813Abstract: This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In some implementations, a heart valve leaflet clipping mechanism includes a delivery apparatus and clipping arms. The clipping arms are coupled to the delivery apparatus. The clipping arms are movable between an open position and a closed position. The two clipping arms are biased to the closed position. The delivery apparatus is configured to hold the clipping arms in the open position. The delivery apparatus is configured to allow the clipping arms to move to the closed position to engage native heart valve leaflet tissue.Type: GrantFiled: December 8, 2022Date of Patent: December 3, 2024Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: Emil Karapetian, Maria Charles Vija Stanislaus, Gregory Bak-Boychuk, Christopher J. Olson, Cristobal R. Hernandez, William C. Brunnett, Netanel Benichou, Lauren R. Freschauf, Alexander J. Siegel, Stanton J. Rowe, Alison S. Curtis
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Patent number: 12115065Abstract: A prosthetic heart valve assembly includes a self-expandable stent having a flared upper portion, a lower portion, and an intermediate portion extending from the upper portion to the lower portion. The stent includes upwardly bent hooks extending from an outer surface of the stent, which are adapted to engage native leaflet tissue. The stent further includes an elongate anchoring member extending from the lower portion of the stent, which is adapted to be secured to a ventricle wall via a prong portion. When deployed within the native heart valve, the flared upper portion contacts a supra-annular surface of the native heart valve for preventing downward migration of the prosthetic heart valve assembly toward the ventricle and the upwardly bent hooks and the elongate anchoring member prevent upward migration of the prosthetic heart valve assembly toward an atrium.Type: GrantFiled: June 13, 2023Date of Patent: October 15, 2024Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: Stanton J. Rowe, Mark Chau, Son V. Nguyen
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Patent number: 12102310Abstract: A septal closure and port device for implantation in the atrial septum of a patient's heart includes an expandable frame with a central portion defining a lumen, and first and second opposing end portions. The frame can expand and contract between a compressed, tubular configuration for delivery through the patient's vasculature and an expanded configuration in which the first and second end portions extend radially outwardly from the opposite ends of the central portion. The device can also have a valve member supported on the frame and positioned to block at least the flow of blood from the left atrium to the right atrium through the lumen of the frame. The valve member permits a medical instrument to be inserted through the lumen and into the left atrium, for performing a subsequent medical procedure in the left side of the heart.Type: GrantFiled: February 22, 2022Date of Patent: October 1, 2024Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: Stanton J. Rowe, Ming H. Wu, Jinny Lee, Ralph Schneider, Sergio Delgado, Ilan Tamir
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Patent number: 12090049Abstract: Prosthetic valve systems for treating a native valve exhibiting regurgitation can include a support structure in which a separate prosthetic heart valve can be placed. A method for implant a prosthetic valve system can include advancing a first catheter delivery sheath through an introducer sheath and into a left ventricle of a patient's heart, deploying at least a portion of a support structure from the first catheter delivery sheath and positioning the support structure around native leaflets of the patient's native mitral valve, positioning a prosthetic heart valve in a radially collapsed configuration within the patient's native mitral valve, and expanding the prosthetic heart valve from the radially collapsed configuration to a radially expanded configuration, wherein the prosthetic heart valve contacts the native leaflets from within the patient's native mitral valve and is separated from the support structure by the native leaflets.Type: GrantFiled: April 1, 2021Date of Patent: September 17, 2024Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: Stanton J. Rowe, Francesco Maisano, Oded Meiri
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Publication number: 20240225469Abstract: Method and devices for treating a physiologic condition of a patient using measurements of pressure of an interstitial space of a patient as an indicator of required therapy.Type: ApplicationFiled: January 13, 2022Publication date: July 11, 2024Applicant: NXT Biomedical, LLCInventors: Robert S. Schwartz, Glen Rabito, Joseph Passman, Stanton J. Rowe, Abubaker Khalifa
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Publication number: 20240216136Abstract: The present invention relates to devices and methods for improving the function of a defective heart valve, and particularly for reducing regurgitation through an atrioventricular heart valve (i.e., mitral valve and/or tricuspid valve). For tricuspid repair, the device includes an anchor deployed in the tissue of the right ventricle, in an orifice opening to the right atrium, or anchored to the tricuspid valve. A flexible anchor rail connects to the anchor and a coaptation element on a catheter rides over the anchor rail. The catheter attaches to the proximal end of the coaptation element, and a locking mechanism fixes the position of the coaptation element relative to the anchor rail. There is a proximal anchoring feature to fix the proximal end of the coaptation catheter subcutaneously adjacent the subclavian vein. The coaptation element includes an inert covering and helps reduce regurgitation through contact with the valve leaflets.Type: ApplicationFiled: March 15, 2024Publication date: July 4, 2024Inventors: Stanton J. Rowe, Robert S. Schwartz, Robert A. Van Tassel, Vivian Khalil, Erin M. Spinner, Neil S. Zimmerman, Alexander J. Siegel
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Publication number: 20240130628Abstract: Method and devices for treating a physiologic condition of a patient using measurements of pressure of an interstitial space of a patient as an indicator of required therapy.Type: ApplicationFiled: January 13, 2022Publication date: April 25, 2024Applicant: NXT Biomedical, LLCInventors: Robert S. Schwartz, Glen Rabito, Joseph Passman, Stanton J. Rowe, Abubaker Khalifa
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Publication number: 20240123202Abstract: Methods and devices that prevent stasis in the LAA by either increasing the flow through the LAA or by closing off or sealing the LAA. Increasing the flow is accomplished through shunts, flow diverters, agitators, or by increasing the size of the ostium. Closing off the LAA is accomplished using seals or by cinching the LAA.Type: ApplicationFiled: December 27, 2023Publication date: April 18, 2024Applicant: NXT Biomedical, LLCInventors: Glen Rabito, Joseph Passman, Robert C. Taft, Stanton J. Rowe, Robert S. Schwartz, Alexander Siegel
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Patent number: 11944538Abstract: A method of reducing regurgitation between native leaflets of an atrioventricular heart valve includes advancing a delivery catheter through a sheath, wherein the delivery catheter has a valve leaflet coaptation element mounted over a distal end portion. The coaptation element is positioned within the heart valve and is permitted to radially expand from a compressed configuration to an enlarged configuration for filling a gap between the native leaflets of the heart valve. After deployment, the position of the coaptation element is fixed relative to the heart valve, thereby reducing regurgitation between the native leaflets of the heart valve and improving heart function.Type: GrantFiled: May 20, 2022Date of Patent: April 2, 2024Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: Stanton J. Rowe, Robert S. Schwartz, Robert A. Van Tassel, Vivian Khalil, Erin M. Spinner, Neil S. Zimmerman, Alexander J. Siegel
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Patent number: 11904120Abstract: Methods and devices that prevent stasis in the LAA by either increasing the flow through the LAA or by closing off or sealing the LAA. Increasing the flow is accomplished through shunts, flow diverters, agitators, or by increasing the size of the ostium. Closing off the LAA is accomplished using seals or by cinching the LAA.Type: GrantFiled: December 20, 2022Date of Patent: February 20, 2024Assignee: NXT Biomedical, LLCInventors: Glen Rabito, Joseph Passman, Robert C. Taft, Stanton J. Rowe, Robert S. Schwartz, Alexander Siegel
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Publication number: 20240041592Abstract: Expandable docking stations for docking an expandable valve can include a valve seat, one or in ore sealing portions, and one or more retaining portions. A system for deploying an expandable docking station can include a catheter having a sleeve for retaining the docking station.Type: ApplicationFiled: October 18, 2023Publication date: February 8, 2024Inventors: Dustin P. Armer, Michael D. Franklin, Sergio Delgado, Abhijeet Joshi, Dinesh L. Sirimanne, Russell T. Joseph, Eason Michael Abbott, Tram Ngoc Nguyen, Son V. Nguyen, Hien Tran Ngo, Vivian Tran, Charles L. Bowman, Stanton J. Rowe
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Publication number: 20240024657Abstract: Described herein are improved blood pumping devices, including improved intra-aortic balloon pumps and ventricular assist devices. The pumping efficiency of either device may be improved with the use of one or more valves, counter pulsation balloons, non-compliant tubular structures, secondary pumping balloons, and similar components.Type: ApplicationFiled: December 9, 2021Publication date: January 25, 2024Applicant: NXT Biomedical, LLCInventors: Robert C. Taft, Alexander Siegel, Glen Rabito, Joseph Passman, Stanton J. Rowe, Elliot Howard, Jeremy Koehler, Robert S. Schwartz, Abubaker Khalifa
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Patent number: 11819403Abstract: An expandable docking station frame includes a waist portion, a sealing portion connected to the waist portion, and a retaining portion connected to the sealing portion. The sealing portion is expandable radially outward of the waist portion to provide a seal against a first location of an inner surface of a circulatory system at a deployed position over a range of sizes of expansion. The retaining portion is expandable radially outward to engage a second location of the inner surface of the circulatory system at the deployed position, to retain the docking station at the deployed position in the circulatory system. When the expandable docking station frame is in an expanded and unconstrained state, the sealing portion and the retaining portion are joined by a concave profile portion radially inward of each of a first outermost diameter of the sealing portion and a second outermost diameter of the retaining portion.Type: GrantFiled: November 24, 2021Date of Patent: November 21, 2023Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: Dustin P. Armer, Michael D. Franklin, Sergio Delgado, Abhijeet Joshi, Dinesh L. Sirimanne, Russell T. Joseph, Eason Michael Abbott, Tram Ngoc Nguyen, Son V. Nguyen, Hien Tran Ngo, Vivian Tran, Charles L. Bowman, Stanton J. Rowe
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Publication number: 20230346552Abstract: A method treating a deficient native mitral valve includes advancing the distal end portion of a delivery catheter into a heart, wherein the delivery catheter contains a support band stretched into a linear form, wherein the support band comprises a shape-memory material, and then ejecting the support band from the distal end portion of the delivery catheter such that the support band transitions from the linear form to a curved shape extending around native leaflets of the native mitral valve.Type: ApplicationFiled: July 11, 2023Publication date: November 2, 2023Inventors: Stanton J. Rowe, Francesco Maisano, Oded Meiri
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Publication number: 20230346548Abstract: Prosthetic heart valves are described. A prosthetic heart valve can include a radially collapsible and expandable frame with a plurality of struts arranged to form a plurality of circumferentially extending rows of closed cells. A prosthetic heart valve can further include a leaflet structure with a plurality of leaflet sections joined to form commissures. The frame includes a plurality of pairs of posts, the posts of each pair spaced apart from each other to define an opening. Each commissure extends radially outwardly through the opening of a respective pair of posts. The pairs of posts have respective lower ends that are axially spaced from a lower end of the frame. An uppermost row of closed cells is formed partly by an uppermost row of circumferentially extending struts interconnecting adjacent posts. A lowermost row of closed cells includes a greater number of closed cells than the uppermost row of closed cells.Type: ApplicationFiled: June 6, 2023Publication date: November 2, 2023Inventors: Netanel Benichou, Stanton J. Rowe, Sean Chow
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Publication number: 20230320847Abstract: A prosthetic heart valve assembly includes a self-expandable stent having a flared upper portion, a lower portion, and an intermediate portion extending from the upper portion to the lower portion. The stent includes upwardly bent hooks extending from an outer surface of the stent, which are adapted to engage native leaflet tissue. The stent further includes an elongate anchoring member extending from the lower portion of the stent, which is adapted to be secured to a ventricle wall via a prong portion. When deployed within the native heart valve, the flared upper portion contacts a supra-annular surface of the native heart valve for preventing downward migration of the prosthetic heart valve assembly toward the ventricle and the upwardly bent hooks and the elongate anchoring member prevent upward migration of the prosthetic heart valve assembly toward an atrium.Type: ApplicationFiled: June 13, 2023Publication date: October 12, 2023Applicant: EDWARDS LIFESCIENCES CORPORATIONInventors: Stanton J. Rowe, Mark Chau, Son V. Nguyen
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Publication number: 20230320877Abstract: Devices and methods of treating conditions cause or exacerbated by excessive fluid pressures or retentions, such as pulmonary hypertension, that involves shunting excessive fluid pressure from one bodily chamber or vessel to another bodily chamber or vessel.Type: ApplicationFiled: June 13, 2023Publication date: October 12, 2023Applicant: NXT Biomedical, LLCInventors: Robert S. Schwartz, Stanton J. Rowe, Robert C. Taft, Glen Rabito, Alexander Siegel, Joseph Passman
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Publication number: 20230263949Abstract: A variety of methods and devices for manipulating tissue using stents and shunts that foreshorten when expanded. Many of the devices have ends that expand radially more than a center portion of the device, creating an hourglass or rivet shape that is useful for anchoring the device or putting a squeezing force on the tissue.Type: ApplicationFiled: June 25, 2021Publication date: August 24, 2023Applicant: NXT Biomedical, LLCInventors: Joseph Passman, Alexander Siegel, Glen Rabito, Stanton J. Rowe, Elliot Howard, Abubaker Khalifa, Robert C. Taft
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Patent number: 11730589Abstract: Prosthetic heart valves are described. Prosthetic heart valves can include radially expandable and compressible inner and outer metal frames. The inner frame can be disposed within a lumen of the outer frame and can be coupled to the outer frame. An outflow end of the inner frame can be coupled to and/or located at an outflow end of the outer frame. An end portion of the inner frame can be spaced radially inwardly from an inner surface of the outer frame, such that a radial gap exists between the inner surface of the outer frame and an outer surface of the inner frame. Prosthetic heart valves can further include a plurality of leaflets disposed within and supported by the inner frame, such as by commissure posts of the inner frame.Type: GrantFiled: July 19, 2021Date of Patent: August 22, 2023Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: Netanel Benichou, Stanton J. Rowe, Sean Chow
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Patent number: 11717399Abstract: An expandable stent for implantation in a right ventricular outflow tract includes a frame having a waist portion that expands to a deployed size having a first diameter, first and second sealing portions extending in opposite directions from the waist portion and expanding radially outward of the waist portion. The first and second sealing portions are sized to seal against first and second portions of the inner surface of the right ventricular outflow tract at the deployed position over a range of sizes of expansion larger than the first diameter. A band is secured to the waist portion of the frame, restricting expansion of the waist portion substantially beyond the first diameter, such that the waist portion is configured to be spaced apart from the inner surface of the right ventricular outflow tract at the deployed position.Type: GrantFiled: January 25, 2022Date of Patent: August 8, 2023Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: Dustin P. Armer, Michael D. Franklin, Sergio Delgado, Abhijeet Joshi, Dinesh L. Sirimanne, Russell T. Joseph, Eason Michael Abbott, Tram Ngoc Nguyen, Son V. Nguyen, Hien Tran Ngo, Vivian Tran, Charles L. Bowman, Stanton J. Rowe