Patents by Inventor Stanton J. Rowe

Stanton J. Rowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10966827
    Abstract: A method of implanting a prosthetic mitral valve includes advancing a delivery apparatus into a left side of a patient's heart and deploying a support structure from the delivery apparatus. The support structure extends around native mitral valve leaflets such that the native leaflets are disposed radially within the support structure. The method also includes advancing a prosthetic heart valve within the native leaflets. The prosthetic heart valve is separate from the support structure and includes an annular frame and a valve structure positioned within the annular frame, and prosthetic heart valve is in a radially collapsed configuration. The method further includes expanding the prosthetic heart valve from the radially collapsed configuration to a radially expanded configuration. In the radially expanded configuration, the annular frame of the prosthetic heart valve engages the native leaflets and is separated from the support structure by the native leaflets.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: April 6, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Stanton J. Rowe, Francesco Maisano, Oded Meiri
  • Publication number: 20210085302
    Abstract: Using a delivery system, a disk is introduced into a left atrium (LA) of a heart of a subject. The left atrial appendage (LAA) is everted into the LA by, the from within the LAA, grasping tissue of the LAA, and pulling the LAA through an ostium of the LAA and into the LA. Within the LA, the disk is expanded, and the perimeter of the everted LAA is sandwiched between a periphery of the disk and the wall around the ostium such that the everted LAA covers the ostium. The everted LAA is secured covering the ostium by anchoring the periphery of the disk around the perimeter of the everted LAA. Other embodiments are also described.
    Type: Application
    Filed: December 9, 2020
    Publication date: March 25, 2021
    Inventors: Stanton J. Rowe, Robert S. Schwartz
  • Patent number: 10952846
    Abstract: A deficient native mitral valve is treated by implanting a prosthetic mitral valve assembly valve in a patient's heart. The prosthetic mitral valve assembly includes a stent having a flared upper portion, an intermediate portion, and a lower portion. The diameter at the inflow end of the stent is larger than at the outflow end. The prosthetic mitral valve assembly also includes a valve portion formed with pericardial tissue leaflets. A tether has a first end attached to the stent and a second end attached to an anchor. The tether extends through a wall of the left ventricle and the tissue anchor is placed outside the left ventricle. After implantation, the flared upper portion resists movement in the downstream direction and the tether resists movement in the upstream direction for securing the prosthetic mitral valve assembly in the native mitral valve.
    Type: Grant
    Filed: January 2, 2019
    Date of Patent: March 23, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Stanton J. Rowe, Mark Chau, Son V. Nguyen
  • Publication number: 20200405480
    Abstract: A prosthetic heart valve can include a support stent, a valve assembly, and a connection structure. The support stent can have an inlet end portion and an outlet end portion, and can be configured to be radially expandable from a crimped configuration to an expanded configuration. The valve assembly can have an inlet, an outlet, and a plurality of leaflets. The connection structure supports the valve assembly in the support stent such that the inlet of the valve assembly is spaced radially inwardly of the support stent and forms an annular space between an inner surface of the support stent and the valve assembly at the inlet of the valve assembly when the support stent is in the expanded configuration. The annular space can have a width in a radial direction between 0.5 cm and 3 cm.
    Type: Application
    Filed: September 9, 2020
    Publication date: December 31, 2020
    Applicant: Edwards Lifesciences Corporation
    Inventor: Stanton J. Rowe
  • Publication number: 20200391016
    Abstract: Methods and techniques are disclosed for performing transcatheter procedures on a patient that result in similar blood flow changes to the surgical Blalock-Taussig procedure, the Glenn procedure, and the Fontan procedure. Since these transcatheter procedures do not necessarily involve open chest surgery, they tend to be less traumatic for the patient, quicker and easier to perform, and may result in better patient outcomes.
    Type: Application
    Filed: June 17, 2020
    Publication date: December 17, 2020
    Applicant: NXT Biomedical
    Inventors: Joseph Passman, Robert S. Schwartz, Robert C. Taft, Stanton J. Rowe, Alexander Siegel, Glen Rabito
  • Publication number: 20200368018
    Abstract: Prosthetic heart valves are described. Prosthetic heart valves can include radially expandable and compressible inner and outer metal frames. The inner frame can be disposed within a lumen of the outer frame and can be coupled to the outer frame. An outflow end of the inner frame can be coupled to and/or located at an outflow end of the outer frame. An end portion of the inner frame can be spaced radially inwardly from an inner surface of the outer frame, such that a radial gap exists between the inner surface of the outer frame and an outer surface of the inner frame. Prosthetic heart valves can further include a plurality of leaflets disposed within and supported by the inner frame, such as by commissure posts of the inner frame.
    Type: Application
    Filed: August 13, 2020
    Publication date: November 26, 2020
    Applicant: Edwards Lifesciences Corporation
    Inventors: Netanel Benichou, Stanton J. Rowe, Sean Chow
  • Publication number: 20200352718
    Abstract: Embodiments of a heart shape preserving anchor are disclosed herein. The heart shape preserving anchor can include a frame having one or more wings extending from a lower end of the frame. The frame can be sized and shaped to distribute forces over a large surface area thereby reducing pressures applied on the heart. The anchor can include a tether for coupling to a prosthesis, such as a replacement heart valve prosthesis. In some embodiments, the anchor can include a tether adjustment mechanism which can be wirelessly operated to adjust a length of the tether relative to the frame.
    Type: Application
    Filed: July 21, 2020
    Publication date: November 12, 2020
    Inventors: Stanton J. Rowe, Yaron Keidar
  • Patent number: 10786353
    Abstract: Disclosed replacement heart valves can be designed to be delivered to a native valve site while crimped on a delivery catheter. The crimped profile of the replacement valve can be minimized by, for example, separating a frame or stent structure from a leaflet structure, along the axial direction. Disclosed replacement valves can be transitioned from a delivery configuration, in which the crimped profile can be minimized, to an operating configuration. The replacement valve can be fully assembled in both the delivery and operating configurations. In some embodiments, the leaflets can be positioned outside of the stent in the delivery configuration, and positioned inside of the stent lumen in the operating configuration. Disclosed replacement valves can include a flexible sleeve coupling the leaflets to the stent and facilitating the transition to the operating configuration. Methods of implanting said replacement valves are also disclosed.
    Type: Grant
    Filed: February 21, 2018
    Date of Patent: September 29, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Netanel Benichou, Stanton J. Rowe, Sean Chow
  • Patent number: 10772723
    Abstract: A prosthetic heart valve can include an expandable support stent, a valve assembly, and a connecting membrane. The support stent can have first and second end portions and can be configured to be radially expandable from a first configuration to a second configuration. The valve assembly can have an inlet portion, an outlet portion, and a plurality of leaflets, and the valve assembly can be supported in the support stent. The connecting membrane can be disposed radially between the support stent and the valve assembly, wherein the support stent and the valve assembly can be connected to the connecting membrane.
    Type: Grant
    Filed: August 17, 2017
    Date of Patent: September 15, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventor: Stanton J. Rowe
  • Patent number: 10722355
    Abstract: Prosthetic valve systems for replacing a native valve exhibiting regurgitation include a support structure and a transcatheter heart valve (THV) that is separate from the support structure. The support structure can be configured to be positioned such that it extends annularly around the native valve leaflets. After the support structure is deployed around the native valve leaflets, the THV can be expanded within the support structure such that the native valve leaflets are engaged between the support structure and the THV.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: July 28, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Stanton J. Rowe, Francesco Maisano, Oded Meiri
  • Publication number: 20200187945
    Abstract: Methods and devices for increasing oxygenation levels in the blood supply and thereby treating the condition of hypoxemia. Multiple approaches such as pressure reduction in the pulmonary circulatory system, reducing triggering mechanisms in the main pulmonary artery and restricting flow in the pulmonary circulatory system are disclosed. Interventions associated with those approaches can including shunting, restrictors, compliance devices, pharmacologic substances, etc.
    Type: Application
    Filed: December 13, 2019
    Publication date: June 18, 2020
    Applicant: NXT Biomedical
    Inventors: Stanton J. Rowe, Robert S. Schwartz, Glen Rabito, Robert C. Taft, Elliot Howard, Alexander Siegel, Joseph Passman
  • Publication number: 20200138568
    Abstract: This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises a main body formed by formed by a plurality of inner members forming an inner clover and a plurality of outer members forming an outer clover. The support frame can include gaps located between inner members of the plurality of inner members and outer members of the plurality of outer members. The inner clover can be radially inside the outer clover, and the outer clover can have larger dimensions than the inner clover. The support frames herein can be radially expandable and collapsible.
    Type: Application
    Filed: January 6, 2020
    Publication date: May 7, 2020
    Inventors: Emil Karapetian, Maria Charles Vija Stanislaus, Gregory Bak-Boychuk, Christopher J. Olson, Cristobal R. Hernandez, William C. Brunnett, Netanel Benichou, Lauren R. Freschauf, Alexander J. Siegel, Stanton J. Rowe, Alison S. Curtis
  • Patent number: 10617520
    Abstract: A method of implanting a prosthetic mitral heart valve includes advancing a guidewire through a femoral vein, an atrial septum, and a native mitral valve. A guide catheter is advanced over the guidewire and a delivery catheter is advanced through the guide catheter. A mitral valve assembly is disposed along a distal end of the delivery catheter. The mitral valve assembly includes a stent and a valve having three leaflets. The stent has a flared inlet end, an outlet end, and an intermediate portion with a plurality of prongs disposed along its outer surface. The mitral valve assembly is deployed with the flared inlet end positioned in a left atrium and the intermediate portion positioned between native mitral valve leaflets. The prongs penetrate surrounding tissue for preventing upward migration of the mitral valve assembly and the flared inlet end is shaped for preventing downward migration.
    Type: Grant
    Filed: August 22, 2017
    Date of Patent: April 14, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Stanton J. Rowe, Mark Chau, Son V. Nguyen
  • Publication number: 20200085600
    Abstract: Devices and methods of treating conditions cause or exacerbated by excessive fluid pressures or retentions, such as pulmonary hypertension, that involves shunting excessive fluid pressure from one bodily chamber or vessel to another bodily chamber or vessel.
    Type: Application
    Filed: September 19, 2019
    Publication date: March 19, 2020
    Applicant: NXT Biomedical
    Inventors: Robert S. Schwartz, Stanton J. Rowe, Robert C. Taft, Glen Rabito, Alexander Siegel, Joseph Passman
  • Publication number: 20200054450
    Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state.
    Type: Application
    Filed: October 28, 2019
    Publication date: February 20, 2020
    Inventors: Stanton J. Rowe, Larry L. Wood, Henry Bourang, George Bakis, Benjamin Spenser, Netanel Benichou, Assaf Bash, Yaron Keidar
  • Publication number: 20200054867
    Abstract: Devices and methods of treating fluid retention caused by congestive heart failure or other conditions resulting in edema, lymphoedema, or significant fluid retention (e.g., deep vein thrombosis, cellulitis, venous stasis insufficiency, or damage to the lymphatic network) are described. Specifically, a treatment device is used to create a passage or cannula between the lymphatic system (or other area of the body) and an external drainage device. This device can be only temporarily located in the patient or can be implanted within the patient for longer periods of time. The physician can safely and reliably remove excess fluid from the body via the device and optionally inject other treatment agents.
    Type: Application
    Filed: August 14, 2019
    Publication date: February 20, 2020
    Applicant: NXT Biomedical
    Inventors: Robert S. Schwartz, Stanton J. Rowe, Alexander Siegel, Joseph Passman, Robert C. Taft, Glen Rabito
  • Patent number: 10517727
    Abstract: Disclosed systems for implanting annuloplasty rings and other prosthetic devices can comprise a plurality of microanchors, sutures threaded through the microanchors, the sutures passing through the prosthetic device, individual microanchor guides, such as tubes or spears, for each microanchor that contain the microanchors during delivery and allow for positioning and deployment of the microanchors into annular tissue. The systems can also comprise a bracket that is temporarily coupled to the prosthetic device, holds the plurality of microanchor guides in position relative to one another and relative to the prosthetic device, and/or guides the sutures passing through the prosthetic device. The prosthetic device can include suture locking mechanisms to secure the prosthetic device to the sutures and to the implanted microanchors after the deployment devices have been removed.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: December 31, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Stanton J. Rowe, Alexander J. Siegel, Ralph Schneider
  • Publication number: 20190358030
    Abstract: Expandable docking stations for docking an expandable valve can include a valve seat, one or more sealing portions, and/or one or more retaining portions. The valve seat can be unexpandable or substantially unexpandable beyond a deployed size. The one or more sealing portions can be connected to the valve seat and extend radially outward of the valve seat. The one or more sealing portions can be constructed to expand outward of the valve seat and provide a seal over a range of sizes. The one or more retaining portions can be connected to the one or more sealing portions. The one or more retaining portions are configured to retain the docking station at a deployed position.
    Type: Application
    Filed: August 7, 2019
    Publication date: November 28, 2019
    Inventors: Dustin P. Armer, Michael D. Franklin, Sergio Delgado, Abhijeet Joshi, Dinesh L. Sirimanne, Russell T. Joseph, Eason Michael Abbott, Tram Ngoc Nguyen, Son V. Nguyen, Hien Tran Ngo, Vivian Tran, Charles L. Bowman, Stanton J. Rowe
  • Patent number: 10456251
    Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: October 29, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Stanton J. Rowe, Larry L. Wood, Henry Bourang, George Bakis, Benjamin Spenser, Netanel Benichou, Assaf Bash, Yaron Keidar
  • Publication number: 20190313774
    Abstract: A method and apparatus for attaching tissue to bone in a shifted position without requiring surgical detachment of muscle or connective tissue joining the tissue layer to the bone layer. The skin layer is gently pulled in a non-surgical manner and a fastener of the invention is driven through the skin layer into the bone layer to effect a “skin tightening” procedure.
    Type: Application
    Filed: June 26, 2019
    Publication date: October 17, 2019
    Applicant: Zift Medical, LLC
    Inventors: Robert S. Schwartz, Stanton J. Rowe, Robert A. Van Tassel, Ralph Schneider, Ming Wu, David John Blaeser, Philip Jon Haarstad, Eric J. Simso, Douglas Jay Krone, Brian Zelickson, Robert A. Ganz, Matt Blaeser, Matt Keillor