Patents by Inventor Starlynn Clarke

Starlynn Clarke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-PSMA ANTIBODIES AND CAR-T STRUCTURES
    Publication number: 20240131074
    Abstract: Anti-PSMA antibodies (e.g., UniAbs™) and CAR-T structures are disclosed, along with methods of making such antibodies and CAR-T structures, compositions, including pharmaceutical compositions, comprising such antibodies and CAR-T structures, and their use to treat disorders that are characterized by the expression of PSMA.
    Type: Application
    Filed: February 25, 2022
    Publication date: April 25, 2024
    Inventors: Starlynn Clarke, Brian Avanzino, Kevin Dang, Nathan Trinklein, Katherine Harris
  • HEAVY CHAIN ANTIBODIES BINDING TO PSMA
    Publication number: 20230242668
    Abstract: Anti-PSMA heavy chain antibodies (e.g., UniAbs™) are disclosed, along with methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat disorders that are characterized by the expression of PSMA.
    Type: Application
    Filed: February 3, 2023
    Publication date: August 3, 2023
    Inventors: Wim van Schooten, Starlynn Clarke, Kevin Dang, Ben Buelow
  • MULTISPECIFIC HEAVY CHAIN ANTIBODIES WITH MODIFIED HEAVY CHAIN CONSTANT REGIONS
    Publication number: 20230203161
    Abstract: Multispecific, human heavy chain antibodies (e.g., UniAbs™) that have modified heavy chain constant regions that impart advantageous properties are provided. The invention further concerns methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat disorders that are characterized by expression of one or more of the binding targets described herein.
    Type: Application
    Filed: April 29, 2021
    Publication date: June 29, 2023
    Inventors: Katherine Harris, Ute Schellenberger, Omid Vafa, Nathan Trinklein, Wim Van Schoofen, Shelley Force Aldred, Duy Pham, Starlynn Clarke
  • ANTI-BCMA HEAVY CHAIN-ONLY ANTIBODIES
    Publication number: 20230060847
    Abstract: Anti-BCMA heavy chain-only antibodies (UniAb) and disclosed, along with methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat B-cell disorders characterized by the expression of BCMA.
    Type: Application
    Filed: August 29, 2022
    Publication date: March 2, 2023
    Inventors: Nathan Trinklein, Shelley Force Aldred, Starlynn Clarke, Wim van Schooten
  • MULTISPECIFIC HEAVY CHAIN ANTIBODIES WITH MODIFIED HEAVY CHAIN CONSTANT REGIONS
    Publication number: 20220332820
    Abstract: Multispecific, human heavy chain antibodies (e.g., UniAbs™) that have modified heavy chain constant regions that impart advantageous properties are provided. The invention further concerns methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat disorders that are characterized by expression of one or more of the binding targets described herein.
    Type: Application
    Filed: November 23, 2021
    Publication date: October 20, 2022
    Inventors: Katherine Harris, Ute Schellenberger, Omid Vafa, Nathan Trinklein, Wim van Schooten, Shelley Force Aldred, Duy Pham, Starlynn Clarke
  • Anti-BCMA heavy chain-only antibodies
    Patent number: 11427642
    Abstract: Anti-BCMA heavy chain-only antibodies (UniAb) and disclosed, along with methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat B-cell disorders characterized by the expression of BCMA.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: August 30, 2022
    Assignee: TENEOONE, INC.
    Inventors: Nathan Trinklein, Shelley Force Aldred, Starlynn Clarke, Wim van Schooten
  • HEAVY CHAIN ANTIBODIES BINDING TO PSMA
    Publication number: 20220195068
    Abstract: Anti-PSMA heavy chain antibodies (e.g., UniAbs™) are disclosed, along with methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat disorders that are characterized by the expression of PSMA.
    Type: Application
    Filed: April 3, 2020
    Publication date: June 23, 2022
    Inventors: Wim van Schooten, Starlynn Clarke, Kevin Dang, Ben Buelow
  • HEAVY CHAIN ANTIBODIES BINDING TO CD38
    Publication number: 20210388106
    Abstract: Binding compounds, such as human heavy-chain antibodies (e.g., UniAbs™) binding to CD38 are disclosed, along with methods of making such binding compounds, compositions, including pharmaceutical compositions, comprising such binding compounds, and their various uses.
    Type: Application
    Filed: October 28, 2019
    Publication date: December 16, 2021
    Inventors: Wim van Schooten, Starlynn Clarke, Kevin Dang
  • Multispecific heavy chain antibodies with modified heavy chain constant regions
    Patent number: 11186639
    Abstract: Multispecific, human heavy chain antibodies (e.g., UniAbs™) that have modified heavy chain constant regions that impart advantageous properties are provided. The invention further concerns methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat disorders that are characterized by expression of one or more of the binding targets described herein.
    Type: Grant
    Filed: May 5, 2021
    Date of Patent: November 30, 2021
    Assignee: TENEOONE, INC.
    Inventors: Katherine Harris, Ute Schellenberger, Omid Vafa, Nathan Trinklein, Wim van Schooten, Shelley Force Aldred, Duy Pham, Starlynn Clarke
  • MULTISPECIFIC HEAVY CHAIN ANTIBODIES WITH MODIFIED HEAVY CHAIN CONSTANT REGIONS
    Publication number: 20210340255
    Abstract: Multispecific, human heavy chain antibodies (e.g., UniAbs™) that have modified heavy chain constant regions that impart advantageous properties are provided. The invention further concerns methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat disorders that are characterized by expression of one or more of the binding targets described herein.
    Type: Application
    Filed: May 5, 2021
    Publication date: November 4, 2021
    Inventors: Katherine Harris, Ute Schellenberger, Omid Vafa, Nathan Trinklein, Wim van Schooten, Shelley Force Aldred, Duy Pham, Starlynn Clarke
  • HEAVY CHAIN ANTIBODIES BINDING TO ECTOENZYMES
    Publication number: 20200207867
    Abstract: Human heavy chain antibodies, such as UniAbs™, binding to ectoenzymes are provided along with combinations of such heavy chain antibodies and multi-specific heavy chain antibodies, targeting non-overlapping epitopes on ectoenzymes, including synergistic combinations. Methods of making such antibodies, compositions including pharmaceutical compositions comprising such antibodies, and methods directed to the treatment of disease or conditions associated with the expression of ectoenzymes are also included.
    Type: Application
    Filed: September 13, 2018
    Publication date: July 2, 2020
    Inventors: Starlynn Clarke, Kevin Dang, Shelley Force Aldred, Nathan Trinklein, Wim van Schooten
  • ANTI-BCMA HEAVY CHAIN-ONLY ANTIBODIES
    Publication number: 20200157232
    Abstract: Anti-BCMA heavy chain-only antibodies (UniAb) and disclosed, along with methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat B-cell disorders characterized by the expression of BCMA.
    Type: Application
    Filed: June 20, 2018
    Publication date: May 21, 2020
    Inventors: Nathan Trinklein, Shelley Force Aldred, Starlynn Clarke, Wim van Schooten