Patents by Inventor Stavros Prionas

Stavros Prionas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10380736
    Abstract: Methods of obtaining a suspect nodules' sizes and/or growth rate are provided. In one embodiment, the method begins with at a first time: (i) obtaining a first three dimensional (3D) data set cube of voxels of a patient's anatomy including nodules; (ii) creating a second 3D data set cube of the same size as the first where all voxel values are set to zero; (iii) creating multiple Maximum-Intensity-Projection (MIP) images from the first 3D data set cube taken at different angles; (iv) replacing those voxels in the second 3D data set cube with corresponding voxels from the first 3D data set cube that provide non-zero values in the multiple MIP images; and (v) converting data in the second 3D data set cube into closed surface volumes, cross sectional areas or linear dimensions using image segmentation. Data from a second time can be used to determine growth rate.
    Type: Grant
    Filed: October 11, 2016
    Date of Patent: August 13, 2019
    Inventors: Larry Partain, George Zentai, Stavros Prionas, Raisa Pavlyuchkova
  • Patent number: 10022565
    Abstract: A method of delivering external radiation beams to a target volume in a body portion includes positioning a radioactive isotope source at a plurality of locations spaced apart around the body portion, and collimating radiation beams of the radioactive isotope source from the plurality of locations, whereby the target volume in the body portion is deposited with a predetermined dose distribution. A radiation device employs a member having a configuration adapted to surround a body portion to be irradiated. The member has a channel and a plurality of collimators spaced apart along and coupled to the channel. The plurality of collimators define a plurality of dwelling locations for a radioactive isotope source in the channel and are configured to collimate radiation beams of the radioactive isotope source.
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: July 17, 2018
    Assignee: Varian Medical Systems, Inc.
    Inventors: Stavros Prionas, Michael C. Green, Edward Seppi, Larry D. Partain, James Clayton, Stanley Mansfield, John Boone
  • Publication number: 20160317839
    Abstract: A method of delivering external radiation beams to a target volume in a body portion includes positioning a radioactive isotope source at a plurality of locations spaced apart around the body portion, and collimating radiation beams of the radioactive isotope source from the plurality of locations, whereby the target volume in the body portion is deposited with a predetermined dose distribution. A radiation device employs a member having a configuration adapted to surround a body portion to be irradiated. The member has a channel and a plurality of collimators spaced apart along and coupled to the channel. The plurality of collimators define a plurality of dwelling locations for a radioactive isotope source in the channel and are configured to collimate radiation beams of the radioactive isotope source.
    Type: Application
    Filed: July 11, 2016
    Publication date: November 3, 2016
    Inventors: Stavros Prionas, Michael C. Green, Edward Seppi, Larry D. Partain, James Clayton, Stanley Mansfield, John Boone
  • Patent number: 9387342
    Abstract: A method of delivering external radiation beams to a target volume in a body portion includes positioning a radioactive isotope source at a plurality of locations spaced apart around the body portion, and collimating radiation beams of the radioactive isotope source from the plurality of locations, whereby the target volume in the body portion is deposited with a predetermined dose distribution. A radiation device employs a member having a configuration adapted to surround a body portion to be irradiated. The member has a channel and a plurality of collimators spaced apart along and coupled to the channel. The plurality of collimators define a plurality of dwelling locations for a radioactive isotope source in the channel and are configured to collimate radiation beams of the radioactive isotope source.
    Type: Grant
    Filed: July 21, 2008
    Date of Patent: July 12, 2016
    Assignee: Varian Medical Systems, Inc.
    Inventors: Stavros Prionas, Michael C. Green, Edward Seppi, Larry D. Partain, James Clayton, Stanley Mansfield, John Boone
  • Patent number: 8935099
    Abstract: Techniques described herein generally relate to identifying, assessing, and managing cancer growth rates and potential metastasis.
    Type: Grant
    Filed: September 19, 2012
    Date of Patent: January 13, 2015
    Assignee: Varian Medical Systems, Inc.
    Inventors: Larry Partain, Mingshan Sun, Edward J. Seppi, Raisa Pavlyuchkova, Arundhuti Ganguly, Stavros Prionas, James E. Clayton
  • Patent number: 8483803
    Abstract: A method for use in a medical procedure includes obtaining a contrast-enhanced image of a portion of a patient, the portion of the patient having an object, obtaining a non-contrast-enhanced image of the portion, wherein the contrast-enhanced image and the non-contrast-enhanced image are created at different times, and determining a position of the object using the contrast-enhanced image and the non-contrast-enhanced image. A method for use in a medical procedure includes obtaining a contrast-enhanced image of a portion of a patient, the portion of the patient having an object, obtaining a non-contrast-enhanced image of the portion, and determining a position of the object using the contrast-enhanced image and the non-contrast-enhanced image, wherein the act of determining the position is performed is substantially real time.
    Type: Grant
    Filed: September 15, 2008
    Date of Patent: July 9, 2013
    Assignee: Varian Medical Systems, Inc.
    Inventors: Larry Partain, Hassan Mostafavi, Stavros Prionas
  • Publication number: 20130071333
    Abstract: Techniques described herein generally relate to identifying, assessing, and managing cancer growth rates and potential metastasis.
    Type: Application
    Filed: September 19, 2012
    Publication date: March 21, 2013
    Applicant: VARIAN MEDICAL SYSTEMS, INC.
    Inventors: Larry PARTAIN, Mingshan SUN, Edward J. SEPPI, Raisa PAVLYUCHKOVA, Arundhuti GANGULY, Stavros PRIONAS, James E. CLAYTON
  • Patent number: 8036435
    Abstract: A method of analyzing a volumetric data set obtained by an imaging system from an object is provided includes defining a first region of interest comprising a population of voxels of a first tissue part of the object to obtain a first distribution of radiation attenuation coefficient values, defining a second region of interest comprising a sample of voxels of a second tissue part of the object to obtain a second distribution of radiation attenuation coefficient values, and distinguishing the second tissue from the first tissue using the properties of the first and second distributions of radiation attenuation coefficients.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: October 11, 2011
    Assignee: Varian Medical Systems, Inc.
    Inventors: Larry Partain, Stavros Prionas, John Boone
  • Publication number: 20100069742
    Abstract: A method for use in a medical procedure includes obtaining a contrast-enhanced image of a portion of a patient, the portion of the patient having an object, obtaining a non-contrast-enhanced image of the portion, wherein the contrast-enhanced image and the non-contrast-enhanced image are created at different times, and determining a position of the object using the contrast-enhanced image and the non-contrast-enhanced image. A method for use in a medical procedure includes obtaining a contrast-enhanced image of a portion of a patient, the portion of the patient having an object, obtaining a non-contrast-enhanced image of the portion, and determining a position of the object using the contrast-enhanced image and the non-contrast-enhanced image, wherein the act of determining the position is performed is substantially real time.
    Type: Application
    Filed: September 15, 2008
    Publication date: March 18, 2010
    Applicant: VARIAN MEDICAL SYSTEMS, INC.
    Inventors: Larry PARTAIN, Hassan MOSTAFAVI, Stavros PRIONAS
  • Patent number: 7660384
    Abstract: A method of imaging a patient's uncompressed region of interest using X-ray cone beam computed tomography or cone beam digital tomography comprises the step of introducing an effective amount of a contrast agent to the uncompressed region of interest. A system for imaging a patient's uncompressed region of interest using cone beam computed tomography (CBCT) or cone beam digital tomography (CBDT) comprises an X-ray source transmitting an X-ray to the uncompressed region of interest, an image acquisition system acquiring a plurality of two-dimensional projection images data for a CBCT or CBDT data set with at least one of the projection images acquired in 35 milliseconds or less, and a processor generating a three-dimensional computed tomography image data set resolving voxels with dimensions of 0.4 mm or less in at least two orthogonal directions.
    Type: Grant
    Filed: May 23, 2008
    Date of Patent: February 9, 2010
    Assignee: Varian Medical Systems, Inc.
    Inventors: Larry Partain, Stavros Prionas, Edward Seppi, Robert Sutherland, David Humber, Hassan Mostafavi, Felix Fernando, John Boone
  • Publication number: 20100016649
    Abstract: A method of delivering external radiation beams to a target volume in a body portion includes positioning a radioactive isotope source at a plurality of locations spaced apart around the body portion, and collimating radiation beams of the radioactive isotope source from the plurality of locations, whereby the target volume in the body portion is deposited with a predetermined dose distribution. A radiation device employs a member having a configuration adapted to surround a body portion to be irradiated. The member has a channel and a plurality of collimators spaced apart along and coupled to the channel. The plurality of collimators define a plurality of dwelling locations for a radioactive isotope source in the channel and are configured to collimate radiation beams of the radioactive isotope source.
    Type: Application
    Filed: July 21, 2008
    Publication date: January 21, 2010
    Applicant: VARIAN MEDICAL SYSTEMS, INC.
    Inventors: Stavros Prionas, Michael C. Green, Edward Seppi, Larry D. Partain, James Clayton, Stanley Mansfield, John Boone
  • Publication number: 20090087045
    Abstract: A method of analyzing a volumetric data set obtained by an imaging system from an object is provided includes defining a first region of interest comprising a population of voxels of a first tissue part of the object to obtain a first distribution of radiation attenuation coefficient values, defining a second region of interest comprising a sample of voxels of a second tissue part of the object to obtain a second distribution of radiation attenuation coefficient values, and distinguishing the second tissue from the first tissue using the properties of the first and second distributions of radiation attenuation coefficients.
    Type: Application
    Filed: September 28, 2007
    Publication date: April 2, 2009
    Inventors: Larry Partain, Stavros Prionas, John Boone
  • Publication number: 20080226018
    Abstract: A method of imaging a patient's uncompressed region of interest using X-ray cone beam computed tomography or cone beam digital tomography comprises the step of introducing an effective amount of a contrast agent to the uncompressed region of interest. A system for imaging a patient's uncompressed region of interest using cone beam computed tomography (CBCT) or cone beam digital tomography (CBDT) comprises an X-ray source transmitting an X-ray to the uncompressed region of interest, an image acquisition system acquiring a plurality of two-dimensional projection images data for a CBCT or CBDT data set with at least one of the projection images acquired in 35 milliseconds or less, and a processor generating a three-dimensional computed tomography image data set resolving voxels with dimensions of 0.4 mm or less in at least two orthogonal directions.
    Type: Application
    Filed: May 23, 2008
    Publication date: September 18, 2008
    Applicant: Varian Medical Systems Technologies, Inc.
    Inventors: Larry D. Partain, Stavros Prionas, Edward Seppi, Robert Sutherland, David Humber, Hassan Mostafavi, Felix Fernando, John Boone
  • Patent number: 7394889
    Abstract: A method of imaging a patient's uncompressed region of interest using X-ray cone beam computed tomography or cone beam digital tomography comprises the step of introducing an effective amount of a contrast agent to the uncompressed region of interest. A system for imaging a patient's uncompressed region of interest using cone beam computed tomography (CBCT) or cone beam digital tomography (CBDT) comprises an X-ray source transmitting an X-ray to the uncompressed region of interest, an image acquisition system acquiring a plurality of two-dimensional projection images data for a CBCT or CBDT data set with at least one of the projection images acquired in 35 milliseconds or less, and a processor generating a three-dimensional computed tomography image data set resolving voxels with dimensions of 0.4 mm or less in at least two orthogonal directions.
    Type: Grant
    Filed: May 18, 2006
    Date of Patent: July 1, 2008
    Assignee: Varian Medical Systems Technologies, Inc.
    Inventors: Larry D. Partain, Stavros Prionas, Edward Seppi, Robert Sutherland, David Humber, Hassan Mostafavi, Felix Fernando, John Boone
  • Publication number: 20070269000
    Abstract: A method of imaging a patient's uncompressed region of interest using X-ray cone beam computed tomography or cone beam digital tomography comprises the step of introducing an effective amount of a contrast agent to the uncompressed region of interest. A system for imaging a patient's uncompressed region of interest using cone beam computed tomography (CBCT) or cone beam digital tomography (CBDT) comprises an X-ray source transmitting an X-ray to the uncompressed region of interest, an image acquisition system acquiring a plurality of two-dimensional projection images data for a CBCT or CBDT data set with at least one of the projection images acquired in 35 milliseconds or less, and a processor generating a three-dimensional computed tomography image data set resolving voxels with dimensions of 0.4 mm or less in at least two orthogonal directions.
    Type: Application
    Filed: May 18, 2006
    Publication date: November 22, 2007
    Inventors: Larry Partain, Stavros Prionas, Edward Seppi, Robert Sutherland, David Humber, Hassan Mostafavi, Felix Fernando, John Boone