Patents by Inventor Steen Hauge Matthiesen

Steen Hauge Matthiesen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR PERFORMING A STRINGENT WASH STEP IN HYBRIDIZATION APPLICATIONS
    Publication number: 20110311974
    Abstract: The invention provides methods and compositions for performing a stringent wash step in a hybridization assay between at least one molecule and a target. The invention may, for example, eliminate the use of, or reduce the dependence on formamide in the stringent wash step. Compositions for use in the invention include an aqueous composition comprising at least one polar aprotic solvent in an amount effective to denature non-complementary sequences in a hybridization product.
    Type: Application
    Filed: December 2, 2009
    Publication date: December 22, 2011
    Inventor: Steen Hauge Matthiesen
  • Compositions and Methods for RNA Hybridization Applications
    Publication number: 20110306047
    Abstract: The invention provides methods and compositions for hybridizing at least one molecule to an RNA target. The invention may, for example, eliminate the use of, or reduce the dependence on formamide in RNA hybridization applications. Compositions for use in the invention include an aqueous composition comprising at least one nucleic acid sequence and at least one polar aprotic solvent in an amount effective to enable hybridization to RNA.
    Type: Application
    Filed: December 2, 2009
    Publication date: December 15, 2011
    Applicant: DAKO DENMARK A/S
    Inventor: Steen Hauge Matthiesen
  • Compositions and Methods for Detection of Chromosomal Aberrations with Novel Hybridization Buffers
    Publication number: 20110281263
    Abstract: The present invention provides compositions and methods for the detection of nucleic acid sequences associated with chromosomal aberrations. The invention may, for example, eliminate the use of or reduce the dependence on formamide in hybridization. Compositions for use in the invention include an aqueous composition comprising at least one nucleic acid sequence and at least one polar aprotic solvent in an amount effective to denature double-stranded nucleotide sequences.
    Type: Application
    Filed: May 27, 2009
    Publication date: November 17, 2011
    Inventors: Steen Hauge Matthiesen, Kenneth H. Petersen, Tim Svenstrup Poulsen
  • Hybridization Compositions and Methods
    Publication number: 20110229975
    Abstract: The invention provides methods and compositions for hybridizing at least one molecule to a target. The invention may, for example, eliminate the use of or reduce the dependence on formamide in hybridization. Compositions for use in the invention include an aqueous composition comprising at least one nucleic acid sequence and at least one polar aprotic solvent in an amount effective to denature double-stranded nucleotide sequences.
    Type: Application
    Filed: May 27, 2009
    Publication date: September 22, 2011
    Inventors: Steen Hauge Matthiesen, Kenneth H. Petersen, Tim Svenstrup Poulsen, Charles M. Hansen
  • APPARATUS AND METHODS FOR PROCESSING BIOLOGICAL SAMPLES AND A RESERVOIR THEREFOR
    Publication number: 20110189782
    Abstract: An apparatus for processing at least one biological sample accommodated on at least one carrier member (15) in a chamber includes, at least one reservoir (18) able to accommodate a fluid on a surface inside the chamber adjacent to and/or facing a substantial part of the at least one biological sample. The apparatus may comprise a bottom member (12) arranged to support at least one carrier member (15) carrying at least one biological sample and a lid (14) including at least one fluid reservoir (18). The reservoir filled with water provides humidity to the chamber and impedes drying out of the sample.
    Type: Application
    Filed: January 28, 2011
    Publication date: August 4, 2011
    Applicant: DakoCytomation Denmark A/S
    Inventors: Gregory A. Testa, Tim Svenstrup Poulsen, Steen Hauge Matthiesen, Ole Feldballe Rasmussen, Lars Winther
  • Apparatus and methods for processing biological samples and a reservoir therefor
    Patent number: 7901634
    Abstract: An apparatus for processing at least one biological sample accommodated on at least one carrier member (15) in a chamber includes at least one reservoir (18) able to accommodate a fluid arranged on a surface inside the chamber adjacent to and/or facing a substantial part of the at least one biological sample. The apparatus may comprise a bottom member (12) arranged to support at least one carrier member (15) carrying at least one biological sample and a lid (14) including at least one fluid reservoir (18). The reservoir filled with water provides humidity to the chamber and impedes drying out of the sample.
    Type: Grant
    Filed: January 7, 2005
    Date of Patent: March 8, 2011
    Assignee: Dako Denmark A/S
    Inventors: Gregory A. Testa, Tim Svenstrup Poulsen, Steen Hauge Matthiesen, Ole Feldballe Rasmussen, Lars Winther