Abstract: A damping system arranged in the region of an injector base between a cylinder head and an injector mounted thereon of an internal combustion engine has a multi-part construction. A damping element forming part of the damping system is constructed as a metal cushion.

Abstract: The invention relates to a method for isolating nucleic acid molecules which are capable of specific interaction with native PrPSc and can differentiate between native PrPc and native PrPSc. The inventive method comprises the following steps: incubating a pool of nucleic acids with purified PrPSc preparations (PPPs); selecting and isolating the resulting protein/nucleic acid complexes and optionally amplifying the specific nucleic acids, in addition to optionally repeating the incubation and isolation stage. The invention also relates to the nucleic acid molecule produced by this method and the use thereof for diagnosing and treating transmissible spongiform encephalopathies.

Abstract: A microfluidic device for metering a fluid or for the metered dispensing of a fluid is provided, the device having a substrate, a pipette element having a dispensing side, which pipette element has a sealed side, and the device also having a heating device in the region of the sealed side. Alternatively, the microfluidic device is provided with the pipette element having a side that is connected to a reservoir, and a heating device in the region of the side connected to the reservoir.

Abstract: In the manufacture of at least one passage in a silicon wafer, in a first method step, starting from a first side of the wafer, a first recess is produced in the wafer, and in a second method step, starting from a second side of the wafer, a second recess is produced in the wafer. The first recess and the second recess are produced such that together they form a passage between the first and second sides of the silicon wafer.

Abstract: The present invention relates to methods for the detection or isolation of prion proteins by use of chaperones specifically binding to said proteins. The invention further relates to a method for in-vitro diagnosis of a transmissible spongiform encephalopathy and to pharmaceutical compositions, preferably for the prevention or treatment of said disease.

Abstract: In a micromechanical sensor and/or a method for manufacturing a micromechanical sensor for detecting a state variable of a substance, the sensor includes at least one heating element, one temperature measuring element and optionally an inlet opening into and/or an outlet opening out of the cavity for this purpose. The sensor includes a cavity configured to at least partially receive the substance through one of the inlet openings and discharge it again at least partially through one of the outlets or outlet openings. The at least one state variable of the substance is detected here as a function of at least one variable representing the operation of the at least one heating element and/or the operation of the at least one temperature element.

Abstract: Pigment concentrates comprising at least one pigment, a polyethylene wax prepared from one ethylene and, if desired, one comonomer using a metallocene catalyst, if desired a thermoplastic polymer and, if desired, additives can be used to color plastic moldings and plastic sheets.

Abstract: The invention relates to a method for passing information between different applications running on one or more computers comprising the following steps:

Abstract: An insert filter 10 for cleaning a gas stream, particularly for the intake air of an internal combustion engine or an air-conditioning unit, which includes a filter frame 11, a filter element 12 placed in the filter frame 11, and a shaft cover 13 and which is placed in the shaft 14 of a duct system 15 that guides the gas stream such that an unfiltered side 16 is separated from a clean side 17 by the filter element 12 and the filter frame 11. The shaft cover 13 closes a shaft opening 24 through which the insert filter 10 is inserted in the shaft 14. The filter frame 11 is connected to the shaft cover 13 so that the filter frame 11 can be removed from the shaft 14 without any need for additional removal aids by simply pulling on the shaft cover 13.

Abstract: The invention describes a process for the identification and isolation of nucleic acid molecules capable of distinguishing the isoforms PrPc and PrPSc of prion proteins as well as nucleic acid molecules obtainable by this process. Furthermore, pharmaceutical compositions and diagnostic compositions are described which comprise nucleic acid molecules specifically binding prion protein isoforms as well as diagnostic methods using such molecules.

Abstract: A filter element formed of a pleated filter medium (11) and having a seal or gasket element (15) on its periphery or end faces. On one side of the filter element, which may represent either the inlet or the outlet side of the filter element, at least one adhesive track or reinforcing member (12, 13, 14), and preferably at least two adhesive tracks or reinforcing members (12, 13, 14), is/are arranged in such a way that the filter element can be bent to a curved configuration in one direction.

Abstract: Emulsifiable ethylene polymers comprising copolymers of from 90 to 95% by weight of ethylene, from 4 to 10% by weight of one or more C3-C12 alkenecarboxylic acids, and from 0 to 1.2% by weight of one or more tertiary esters of the corresponding C3-C12 alkenecarboxylic acids, where the wax has a cinematic melt viscosity of from 800 to 3000 mm2/s, measured at 120° C.; and a process for preparing the novel emulsifiable ethylene polymers, emulsions comprising the novel ethylene polymers, a process for preparing the emulsions from the novel ethylene polymers, and also floor cleaners, car cleaners, leather cleaners and stone cleaners, and coatings for surfaces made from wood, metal, paper, glass or from plastics, comprising aqueous emulsions of the novel emulsifable waxes.

Abstract: Pigment concentrates comprising at least one pigment, a polyethylene wax prepared from one ethylene and, if desired, one comonomer using a metallocene catalyst, if desired a thermoplastic polymer and, if desired, additives can be used to color plastic moldings and plastic sheets.

Abstract: The present invention relates to methods for the detection or isolation of prion proteins by use of chaperones specifically binding to said proteins. The invention further relates to a method for in vitro diagnosis of a transmissible spongiform encephalopathy and to pharmaceutical compositions, preferably for the prevention or treatment of said disease.

Abstract: A printed circuit board tester includes an electronic analyzer and a grid pattern of contact points arranged in a regular pattern in a grid pattern plane. The contact points of the grid pattern are electrically connected to the electronic analyzer such that test points of a circuit board can be electrically scanned, whereby several contact points of the grid pattern are electrically interconnected. The circuit board is connectable to the contact points of the grid pattern by an adapter and/or a translator. The tester includes several grid bases, each of which comprises a contact point narrow side surface at which the contact points are arranged. The grid bases are provided with tracks, each of which is electrically connected to several contact points. Each track includes an electrical terminal connection leading to a terminal contact for connecting the electronic analyzer such that several contact points are electrically connected to a terminal contact.

Abstract: A filter material for separating solid, particulate and gaseous components from fluids, which is enclosed on both the upstream and downstream sides with a particle filtering medium.

Abstract: The invention describes a process for the identification and isolation of nucleic acid molecules capable of distinguishing the isoforms PrPc and PrPSc of prion proteins as well as nucleic acid molecules obtainable by this process. Furthermore, pharmaceutical compositions and diagnostic compositions are described which comprise nucleic acid molecules specifically binding prion protein isoforms as well as diagnostic methods using such molecules.

Abstract: The present invention relates to pharmaceutical compositions comprising a soluble laminin receptor precursor (LRP) or a modification thereof. The present invention also relates to pharmaceutical compositions comprising a compound which blocks the interaction of LRP and PrPSc or PrPc. Said compositions allow the treatment of diseases associated with the presence of PrPSc. In addition, the present invention provides an expression vector for the recombinant production of LRP or any other kind of protein in the baculovirus system.

Abstract: An insert filter 10 for cleaning a gas stream, particularly for the intake air of an internal combustion engine or an air-conditioning unit, which includes a filter frame 11, a filter element 12 placed in the filter frame 11, and a shaft cover 13 and which is placed in the shaft 14 of a duct system 15 that guides the gas stream such that an unfiltered side 16 is separated from a clean side 17 by the filter element 12 and the filter frame 11. The shaft cover 13 closes a shaft opening 24 through which the insert filter 10 is inserted in the shaft 14. The filter frame 11 is connected to the shaft cover 13 so that the filter frame 11 can be removed from the shaft 14 without any need for additional removal aids by simply pulling on the shaft cover 13.

Abstract: An optically controllable microelectrode array for stimulating cells within a tissue is disclosed. The array comprises a substrate having a surface. The substrate is adapted to be placed on the tissue with the surface adjoining the cells. The substrate further comprises a plurality of electrodes on the surface in contact with the cells for stimulating the cells. The electrodes are dimensioned such that a first surface area on the electrodes in contact with the cells is essentially smaller than a second surface area on the cells in which the cells may be contacted by the electrodes. An electrical stimulus is exerted from the electrodes to the cells under the control of light impinging on the tissue.