Abstract: An electronically-controlled capturing system for capturing data representing an amount of a drug expelled or discharged from a drug reservoir includes an electronic circuit including an electric energy unit, a processing unit operable by electric power obtained from the electric energy unit and operable to acquire data, and an electronic storage unit connected to the processing unit and configured to store the acquired data. The processing unit is operable to write the acquired data in the storage unit and is operable to read and provide the stored data from the electronic storage unit. The capturing system also includes a data reading disabling unit operably connected to the processing unit , the electronic storage unit and/or the electric energy unit. The data reading disabling unit is switchable into an activated state, in which the data reading disabling unit persistently prevents readout or providing of stored data from the electronic storage unit.

Abstract: The present disclosure relates to an injection device for setting and injecting of a dose of a medicament. The injection device includes an elongated housing extending along a longitudinal direction and configured to accommodate a cartridge, a first member movably arranged inside the elongated housing for setting of the dose, and a second member, and a piston rod configured to advance in a longitudinal distal direction and operable to exert a distally directed pressure onto a bung of the cartridge for expelling of the dose. Depending on the setting, the first member is rotatable relative to the second member or is rotationally locked to the second member. The injection device includes a filling level indicator threadedly engaged with one of the first member and the second member, the filling level indicator being rotationally locked and longitudinally slidingly engaged with the other one of the first member and the second member.

Abstract: The present disclosure relates to a drug delivery device. The drug delivery device comprises a drug container containing a drug liquid, wherein the drug liquid includes insulin glargine dissolved therein, and a hollow needle defining an elongated interior space through which the drug liquid is dispensable from the drug container, wherein the needle is at least partially made of a steel resistant to chloride, wherein the elongated interior space is in fluid communication with the drug container in a storage or pre-delivery condition, for example within a timeframe of at least 1 hour in absence of significant exchange of drug liquid inside the interior space.

Abstract: A drug delivery device comprising a first module comprising a zinc-air cell located at one end of the first module, a second module for attachment to the one end of the first module and comprising electronics, and activation means for activating the zinc-air cell and being designed such that at least one air hole is created in an air tight sealing of the zinc-air cell when the second module is attached to the one end of the first module.

Abstract: An assembly for a drug delivery device, the assembly comprising: a housing unit, the housing unit comprising a housing for receiving a reservoir and a dispensing mechanism configured to dispense liquid drug content from the reservoir in a dispensing operation, a cap which is releasably connected to the housing unit, the cap, when connected to the housing unit, at least partially covers a distal dispensing end of the assembly, which is uncovered when the cap is disconnected from the housing unit, a first information feature having coded first content, wherein the first information feature is machine-readable to retrieve the first content from the first information feature, a second information feature, wherein the first information feature is visible and/or machine-readable when the cap is connected to the housing unit and removable together with the cap from the housing unit or rendered unreadable when the cap is disconnected from the housing unit.

Abstract: A drug delivery device, comprising: a housing, a plunger arranged within the housing and movable along the longitudinal axis and adapted to push a piston within a container in a distal direction, the plunger being prevented from rotating and comprising an external thread, a drive nut arranged within the housing and comprising an internal thread engaging the thread of the plunger, an axial bearing arranged between the drive nut and the housing to limit axial movement of the drive nut relative to the housing, a mechanism configured to exert a force on the drive nut in the distal direction through a rotatable component coupled to the drive nut for joint rotation and at least one non-rotatable component, wherein a bearing is arranged between the at least one rotatable component and the at least one non-rotatable component, the bearing having a smaller diameter than the axial bearing.

Abstract: An assembly for a drug delivery device comprises: a housing having a proximal end and a distal end, a dose setting and drive mechanism comprising a dose setting member moveable relative to the housing in a dose setting operation from an initial position to a dose set position, the dose setting and drive mechanism further comprising a piston rod displaceable in the distal direction relative to the housing in a dose delivery operation, wherein, during the dose delivery operation, the piston rod is displaced relative to the housing by a displacement distance which is determined by the set dose, a guide track, a tracking member configured to cooperate with the guide track, and a coupling mechanism configured to operatively couple the tracking member to the dose setting and drive mechanism, wherein the coupling mechanism has a coupled state and a non-coupled state.

Abstract: The present disclosure relates to a flexible container for an injection device including a flexible bag having an interior volume to be filled with a liquid medicament, an outlet located at a first end of the bag, and a contraction member connected to the bag to displace a second end of the bag located opposite to the first end towards the first end.

Abstract: The present disclosure relates to an injection device configured to expel a dose of a medicament, the injection device comprising: an elongated housing extending in a longitudinal direction, a piston rod movable relative to the housing in a longitudinal distal direction to exert a dispensing pressure onto a bung of a cartridge at least partially filled with an injectable medicament, a rod extension movably arranged on or in a distal end of the piston rod, a driver operably engaged with the piston rod and movable relative to the housing in a longitudinal proximal direction for setting of the dose and movable relative to the housing in the longitudinal distal direction for dispensing of the dose, and an adjuster arranged on or in the driver and operably engaged with the rod extension to move the rod extension in longitudinal direction relative to the piston rod.

Abstract: Described herein are specialized needle assemblies for injection systems. One example injection system includes a needle assembly configured to removably attach to a drug delivery device and a housing configured to receive a drug cartridge. The needle assembly includes a needle configured to extend through an outlet port of the drug delivery device and establish fluid communication with the drug cartridge within the housing of the drug delivery device. The needle assembly may include a fluid flow sensor monitoring the fluid flow and/or occlusions within the needle assembly, and provide indications of an occluded or clogged needle and/or one or more indications of proper flow through the needle, e.g., non-occlusion of the needle. In some examples, the arrangement of the needle assembly includes sensors to detect an occlusion within a portion of a needle.

Abstract: An injection device comprises a housing with a receptacle for the product, a dosing mechanism for setting a product dosage, a dispensing mechanism for dispensing the product, at least one sleeve, which is rotatable relative to the housing in order to eject the set product dosage, and a stop wheel coupled to the at least one sleeve such that the stop wheel is rotatable relative to the housing and the at least one sleeve for setting a product dosage and together with the at least one sleeve relative to the housing in order to eject the set product dosage. The device further comprises a first detector for detecting movement of the stop wheel relative to the housing and/or the at least one sleeve and a data processing unit connected to the first detector reading, storing, processing, transmitting, and/or displaying signals received from the first detector.

Abstract: An assembly for a drug delivery device is presented. The assembly comprises a housing and a piston rod having a longitudinal axis, a distal end and a proximal end. The piston rod further comprises a piston rod interaction feature, and a piston rod guide being movable with respect to the piston rod, the piston rod guide further comprising a guide interaction feature corresponding to the piston rod interaction feature, the piston rod guide being movable with respect to the piston rod to switch between a first state and a second state of the assembly, the second state being different from the first state.

Abstract: A drive mechanism for a drug delivery device with a reduced operating loudness includes a dose selector, a housing, and a ratchet with a gear element comprising a plurality of gear teeth connected with the dose selector and a pawl element rotationally constrained to the housing comprising at least one pawl tooth. The at least one pawl tooth engages with the gear teeth and is located opposite to the gear teeth. One of the gear element and the pawl element moves forth and back relative to the other element of the gear and pawl elements along a first direction for de-engagement and re-engagement of the opposite gear teeth and at least one pawl tooth when the gear element rotates relative to the housing during dose setting using the dose selector.

Abstract: An assembly for a drug delivery device is provided comprising a housing, and a lead screw having a longitudinal axis, a distal end and a proximal end, the lead screw being rotatably fixed during dose setting and dose delivery and axially movable in a distal direction relative to the housing, the lead screw further including a thread. The assembly further comprises a drive nut threadedly engaged with and screwable along the lead screw thread and a dial link connected with the drive nut and axially movable and rotatably fixed relative to the drive nut, where the dial link comprises a first portion of a feedback ratchet. The assembly is configured such that, during dose delivery, the assembly generates a feedback signal.

Abstract: An injection device comprising a housing with a receptacle for the product, a dosing mechanism for setting a product dosage to be administered and for displaying the set product dosage and a dispensing mechanism for dispensing the product. The dispensing mechanism may include a piston rod, at least one sleeve rotatable relative to the housing to eject the set product dosage, and a button moveable relative to the housing and relative to the at least one sleeve in the dispensing direction from a dosing position into a dispensing position to eject the set product dosage. The device can further include a first detector for detecting the position of the button relative to the housing or the at least one sleeve, a second detector for detecting rotational movement of the at least one sleeve or a component part coupled to the at least one sleeve and a feedback generator mechanism.

Abstract: A drive train for a wind-up injection device, comprises a torsional energy storage adapted to be loaded or unloaded by a rotatable element, a rotatable user handle coupled with a button, a rotationally drivable expelling mechanism, and a clutch element coupled with the torsional energy storage via the rotatable element and comprising a ratchet for maintaining the rotatable element at one of a number of discrete angular positions, wherein via the rotatable element, the clutch element is adapted to transmit a torque from the user handle to the torsional energy storage or from the torsional energy storage to the expelling mechanism, and wherein the ratchet is switchable from one position to an adjacent position by a torque transmitted from the user handle to the torsional energy storage, and wherein the drive train is adapted to dampen torque peaks by a flexible impact portion in the area of the clutch element.

Abstract: An injection device comprises a housing with a receptacle for a product, a dosing mechanism for setting a product dosage to be administered and for displaying the product dosage that has been set, and a dispensing mechanism for dispensing the product. The dosing mechanism comprises a dosing sleeve which is rotatable relative to the housing in a first direction for setting a product dosage and which is rotatable relative to the housing in a second, opposite direction for correcting or dispensing a product dosage. The dispensing mechanism comprises a piston rod, at least one sleeve, and a clutch. The device further comprises a first detector for detecting movement of the clutch relative to the dosing sleeve and/or the housing and/or the at least one sleeve and a data processing unit connected to the first detector for reading, storing, processing, transmitting, and/or displaying signals received from the first detector.

Abstract: A system comprises a first member, a second member, and a third member, wherein the first and second members are rotatable relative to the third member, wherein the first and second members are coupled to one another by a dead-angle follower coupling, wherein the dead-angle follower coupling is configured such that the first and second members are rotatable relative to one another, wherein the second and third members are rotationally coupled to one another by a switchable coupling mechanism, wherein the switchable coupling mechanism is switchable between two different states, a locked state and a non-locked state, wherein the maximum torque transferable between the second and third members via the switchable coupling mechanism in the locked state is greater than in the non-locked state, wherein the switchable coupling mechanism is in the locked state when the first member is in a locking position relative to the second member.

Abstract: A drug delivery device is provided having a housing, a lead screw that is rotatably fixed with respect to the housing during dose setting and during dose delivery and that is axially moveable in a delivery direction relative to the housing for dose delivery, a number sleeve threadedly engaged with the housing to be screwable relative to the housing, and a dial link which is axially moveable and rotatable with respect to the housing for dose setting and which is prevented from rotation with respect to the housing for dose delivery. The dial link is rotatably fixed with the number sleeve when the dial link and the number sleeve are in a first arrangement, and the number sleeve and the dial link are rotatable with respect to one another when the dial link and the number sleeve are in a second arrangement.

Abstract: A drive train (T) for a wind-up injection device (1) for injecting a liquid drug comprises a torsional energy storage (9) adapted to be loaded or unloaded by a rotatable element (6), a rotatable user handle (8), a rotationally driveable expelling mechanism (5) adapted to expel the liquid drug and a clutch element (12) coupled with the torsional energy storage (9) via the rotatable element (6) and comprising a ratchet (12.4) for maintaining the rotatable element (6) at one of a number of discrete angular positions against the torque of the torsional energy storage (9). The clutch element (12) is adapted to transmit a torque from the user handle (8) via the rotatable element (6) to the torsional energy storage (9) or alternatively from the torsional energy storage (9) via the rotatable element (6) to the expelling mechanism (5), wherein the ratchet (12.4) is switchable from one position to an adjacent position by a torque transmitted from the user handle (8) to the torsional energy storage (9).