Abstract: A positioning system, including: a first plate; a second plate coupled to the first plate and pivotable about an axis; a pair of voice coil actuators configured to rotate the second plate about this axis; and a processor configured to drive currents to the pair of voice coil actuators; wherein the pair of voice coil actuators comprises a first and second magnet structures mounted on the first plate at equal and opposite distance from the axis, and a first and second coils mounted on the second plate and positioned such that the respective first and second magnet structures move in and out of the first and second coils when the second plate rotates about the axis; wherein each of the first and second magnet structures substantially conforms to an arc having a center at the axis and a radius equal to the distance of the magnet structure from the axis.

Abstract: Methods of modulating eosinophil migration, chemotaxis or generation, in vitro, ex vivo, and in vivo are provided. Methods include contacting eosinophils with an amount of 5-HT2A receptor agonist or antagonist sufficient to modulate eosinophil migration, chemotaxis or generation.