Patents by Inventor Stefan Floess

Stefan Floess has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection and quality control of regulatory T cells through DNA-methylation analysis of the Foxp3 gene
    Patent number: 10876163
    Abstract: The present invention relates to a method, in particular an in vitro method for identifying FoxP3-positive regulatory T cells, preferably CD25+CD4+ regulatory T cells of a mammal, comprising analysing the methylation status of at least one CpG position in the gene foxp3 or an orthologous or paralogous gene thereof, and the use of DNA-methylation analysis of the gene of the transcription factor FoxP3 for a detection and quality assurance and control of regulatory T cells. Furthermore, the present invention relates to a kit for performing the above methods as well as respective uses.
    Type: Grant
    Filed: February 28, 2007
    Date of Patent: December 29, 2020
    Assignees: Epiontis GmbH, Charite-Universitatsmedizin Berlin
    Inventors: Jochen Huehn, Stefan Floess, Alf Hamann, Sven Olek, Udo Baron
  • Detection and quality control of regulatory T cells through DNA-methylation analysis of the Foxp3 gene
    Publication number: 20070269823
    Abstract: The present invention relates to a method, in particular an in vitro method for identifying FoxP3-positive regulatory T cells, preferably CD25+CD4+ regulatory T cells of a mammal, comprising analysing the methylation status of at least one CpG position in the gene foxp3 or an orthologous or paralogous gene thereof, and the use of DNA-methylation analysis of the gene of the transcription factor FoxP3 for a detection and quality assurance and control of regulatory T cells. Furthermore, the present invention relates to a kit for performing the above methods as well as respective uses.
    Type: Application
    Filed: February 28, 2007
    Publication date: November 22, 2007
    Inventors: Jochen Huehn, Stefan Floess, Alf Hamann, Sven Olek, Udo Baron