Abstract: Methods of treating and evaluating subjects having neoactive mutants are described herein.

Abstract: A cable guidance system for a computed tomography system, wherein a gantry of the computed tomography system is repositionable in a direction of movement perpendicular to the gantry, the cable guidance system comprising: a vertical column arranged on the gantry and running vertically upward from a base of the computed tomography system; and a first articulated arm and a second articulated arm. The first articulated arm is rotatably connected to an upper end of the vertical column above the gantry via a first point of articulation, and rotatably connected, via a second point of articulation, to the second articulated arm which is likewise arranged above the gantry. At least one supply line runs in a repositionably guided manner along longitudinal axes of the first and second articulated arms.

Abstract: A cable routing system for a computed tomography system having a gantry configured to be adjusted in a movement direction extending perpendicular to the gantry, the cable routing system comprising: a vertical column arranged on the gantry and extending vertically from a base of the computed tomography system; and a first and a second articulated arm. The first articulated arm is rotatably attached to an upper end of the vertical column above the gantry via a first point of articulation. The first articulated arm is also rotatably attached to the second articulated arm, which is also arranged above the gantry, via a second point of articulation. The vertical column and the first and the second articulated arm are configured to route at least one supply line at least in part along their respective longitudinal axes.

Abstract: A conditioning roller assembly includes two conditioning rollers which are rotatably mounted on associated bearing arrangements, and a holder which includes a first holder component and a second holder component that are connected together by a hinge and a spring arrangement for providing a pre-tensioning of the conditioning rollers. The first holder component is releasably connected to the first bearing arrangement, the second holder component is releasably connected to the second bearing arrangement, and the conditioning rollers, with the bearing arrangements, are detachable in each case from the components without the holder being disassembled.

Abstract: The invention relates to a transport vehicle for transporting at least one transport unit. The transport vehicle including at least one drive unit having at least one electric drive, at least one steerable vehicle wheel, at least one standing platform, at least one control unit (6), and at least one loading fork, and at least two longitudinal outriggers, which are arranged parallel to one another and at a distance from one another and extend in a longitudinal direction of the transport vehicle and between which the loading fork is arranged so as to be height-adjustable and which are in each case connected to the drive unit by one end section and at the respective other end section of which in each case at least one non-steerable vehicle wheel is arranged.

Abstract: A conditioning roller assembly includes a first conditioning roller which is rotatably mounted on a first holder, a second conditioning roller which is rotatably mounted on a second holder, and a pivoting arrangement which includes a first component and a second component which are connected together by a hinge with an axis extending parallel to the longitudinal axes of the conditioning rollers, and a resilient arrangement for providing pre-tensioning of the conditioning rollers. The first holder and/or the second holder is mounted so as to be pivotable in each case about a pivot axis relative to the associated first component and/or second component for servicing purposes.

Abstract: A base body of a computed tomography drum is disclosed. In an embodiment, the base body includes at least the following components: a base plate, an outer ring and an inner ring. The inner ring is arranged concentrically with the outer ring. The outer ring and the inner ring are arranged on the base plate. At least two of the components are configured as separately producible components. Two of the separately producible components are connected to one another by way of at least one of: bonding, welding, riveting, clinching, clinch-bonding and/or rivet-bonding.

Abstract: The invention relates to a transport vehicle for transporting at least one transport unit. The transport vehicle including at least one drive unit having at least one electric drive, at least one steerable vehicle wheel, at least one standing platform, at least one control unit (6), and at least one loading fork, and at least two longitudinal outriggers, which are arranged parallel to one another and at a distance from one another and extend in a longitudinal direction of the transport vehicle and between which the loading fork is arranged so as to be height-adjustable and which are in each case connected to the drive unit by one end section and at the respective other end section of which in each case at least one non-steerable vehicle wheel is arranged.

Abstract: A conditioning roller assembly includes two conditioning rollers which are rotatably mounted on associated bearing arrangements, and a holder which includes a first holder component and a second holder component that are connected together by a hinge and a spring arrangement for providing a pre-tensioning of the conditioning rollers. The first holder component is releasably connected to the first bearing arrangement, the second holder component is releasably connected to the second bearing arrangement, and the conditioning rollers, with the bearing arrangements, are detachable in each case from the components without the holder being disassembled.

Abstract: A medical examination or treatment facility includes a C-arm, arranged on a support bracket of a robot configured to move the C-arm in space. In an embodiment, the C-arm is made up of a plurality of arm elements in the form of sheet metal parts and at least one coupling unit including at least one cast metal part for coupling the C-arm to the support bracket.

Abstract: Methods of treating and evaluating subjects having neoactive mutants are described herein.

Abstract: A test equipment has a signal input/signal output and a use-site calibration unit for determining a user-site compensation function. The user-site compensation function has a compensation magnitude function and a compensation Hilbert phase function. The calibration unit has a level meter and a calculator. The level meter is configured to measure a magnitude characteristic of the electrical signal, the magnitude characteristic being the basis for the determination of the compensation Hilbert phase function. The calculator is configured to determine a Hilbert phase characteristic of the electrical signal based on a Hilbert transformation of a function dependent on the measured magnitude characteristic and to determine the compensation Hilbert phase function on the basis of the Hilbert phase characteristic.

Abstract: A roller shell for a conditioning roller includes a number of teeth which are distributed over the periphery thereof and which extend in an axial direction. Each of the teeth includes a leading flank, a trailing flank and a radial outer surface region having an angulation defined therein. The angulation may include a recess or a step in the outer surface region.

Abstract: Methods of diagnosing subjects having a cell proliferation-related disorder or suspected of having a cell proliferation-related disorder associated with mutant IDH enzymes with 2HG neoactivity.

Abstract: An examination and/or treatment device includes a multi-axis robot having an articulated arm that can be moved in space as well as leads received in a flexible cladding tube and guided to one or more examination or treatment devices arranged on the articulated arm or a support arranged thereon. In an embodiment, on the articulated arm is provided a carriage arrangement including a carriage, having at least one deflection roller and that can be linearly displaced against at least one restoring element that builds up a restoring force. The cladding tube or a guide tube surrounding the cladding tube is guided around the deflection roller.

Abstract: Methods of treating and evaluating subjects having neoactive mutants are described herein.

Abstract: A combination of a CHK1 inhibitor and a WEE1 inhibitor are provided.

Abstract: Methods of treating and evaluating subjects having neoactive mutants of IDH (e.g., IDH1 or IDH2).

Abstract: An examination and/or treatment device includes a multi-axis robot having an articulated arm that can be moved in space as well as leads received in a flexible cladding tube and guided to one or more examination or treatment devices arranged on the articulated arm or a support arranged thereon. In an embodiment, on the articulated arm is provided a carriage arrangement including a carriage, having at least one deflection roller and that can be linearly displaced against at least one restoring element that builds up a restoring force. The cladding tube or a guide tube surrounding the cladding tube is guided around the deflection roller.

Abstract: A medical examination or treatment facility includes a C-arm, arranged on a support bracket of a robot configured to move the C-arm in space. In an embodiment, the C-arm is made up of a plurality of arm elements in the form of sheet metal parts and at least one coupling unit including at least one cast metal part for coupling the C-arm to the support bracket.