Abstract: A method for determining system excitation by at least one input signal for model-based control of a technical system includes (i) providing the at least one input signal, wherein the at least one input signal physically affects at least one parameter of the technical system, (ii) defining at least one distribution assumption for the at least one parameter, (iii) defining a target function for optimizing the at least one input signal taking into account the at least one defined distribution assumption, the target function optimizing the at least one input signal at least based on a weighting of a sensitivity of the input signal, (iv) determining a numerical algorithm for solving the defined target function and an uncertainty quantification method for determining the sensitivity of the at least one input signal, (v) optimizing the defined target function based on the determined numerical algorithm and the determined uncertainty quantification method, and (vi) determining the system excitation based on the opti

Abstract: In a device and method for determining a filter output variable of a filter, in particular of a filter for filtering a torsion bar moment of a steer-by-wire steering system of a vehicle, as a function of a filter input variable to be filtered, a predefined filter property of the filter is selected from a plurality of predefined filter properties depending on an input signal characteristic of the filter input variable. The input signal characteristic is determined depending on the filter input variable at a current point in time and at least one previous point in time, and the filter output variable of the filter is determined using the filter property.

Abstract: A method is for manufacturing a controller for a control section including a rack of a steering system of a vehicle. The method includes providing measurements characterizing an actual behavior of the control section at different operating points, and specifying a target behavior of the rack. The method also includes determining functions modeling a deviation of the actual behavior from the target behavior at a respective operating point for each one of the different operating points depending on the measurements. At least one parameter of the controller affects an actual transmission behavior of the control section. The at least one parameter includes a proportional gain factor, an integral gain factor, and/or a differential gain factor of the controller, and is determined depending on the deviations determined for the different operating points, such that the control section has a specified target transmission behavior.

Abstract: The present disclosure provides lipocalin muteins capable of binding CTGF as well as fusion proteins comprising said muteins, which are useful for analytical, diagnostic or therapeutical purposes, for example in the treatment of a fibrotic disease, a cancer, an autoimmune disease, or an infectious disease. The present disclosure also concerns methods of making the lipocalin muteins or fusion proteins described herein. The present disclosure further relates to nucleic acid molecules encoding such lipocalin muteins or fusion proteins. In addition, the present disclosure relates to therapeutic and/or diagnostic uses of such lipocalin muteins or fusion proteins as well as to compositions comprising one or more of such lipocalin muteins or fusion proteins.

Abstract: The disclosure provides multimeric proteins comprising three, four, or more monomer polypeptides, each comprising a first 4-1BB-targeting moiety, an oligomerization moiety, and optionally a linker. The monomer polypeptide may further comprise one or more additional targeting moieties. The oligomerization moiety promotes the trimerization, tetramerization, or higher state of oligomerization of the monomer polypeptides. Such multimeric proteins can be used in many pharmaceutical applications, for example, as anti-cancer agents and/or immune modulators. The present disclosure also concerns methods of making the multimeric proteins described herein as well as compositions comprising such multimeric proteins. The present disclosure further relates to nucleic acid molecules encoding such multimeric proteins and methods for the generation of such multimeric proteins and nucleic acid molecules.

Abstract: In an electric steering device, a plurality of periodic disturbances (M(f1o), M(f2o), . . . M(fno)) can occur which are to be compensated, while additionally occurring, in particular non-periodic, disturbances (Mstoer) are not to be compensated.

Abstract: In an electric steering device, a plurality of periodic disturbances (M(f1o), M(f2o), . . . M(fno)) can occur which are to be compensated, while additionally occurring, in particular non-periodic, disturbances (Mstoer) are not to be compensated. So as to enable simultaneous compensation of a plurality of such periodic disturbances based on a model (Gnom(s)) of the steering device, it is proposed to map the further disturbances Mstoer occurring in addition to the disturbances M(f1o), M(f2o), (Mfno) to be compensated, together with inaccuracies or modeling errors (?s) of the model (Gnom(s)) in the form of an unstructured disturbance (Mstoer).

Abstract: A torque actuator is regulated so as to permit an activation of the torque actuator such that steering wheel rotary oscillations that occur can be compensated. For this purpose, in one embodiment, a torsion bar torque is detected. A compensation torque is determined as a function of the detected torsion bar torque by means of a variable-frequency disturbance variable and state variable calculator. The compensation torque or a signal corresponding to the compensation torque is then taken into consideration during activation of the torque actuator.

Abstract: A torque actuator is regulated so as to permit an activation of the torque actuator such that steering wheel rotary oscillations that occur can be compensated. For this purpose, in one embodiment, a torsion bar torque is detected. A compensation torque is determined as a function of the detected torsion bar torque by means of a variable-frequency disturbance variable and state variable calculator. The compensation torque or a signal corresponding to the compensation torque is then taken into consideration during activation of the torque actuator.

Abstract: Provided is a way of using an estimator to determine a force (Fz), which acts from the outside on a steering gear of a steering device in a vehicle by way of a steering linkage, wherein a motor for generating a steering torque is assigned to the steering device. This is achieved by estimating the force (Fz) acting from the outside as a function of an effective motor torque (tor_RAeff), wherein the effective motor torque (tor_RAeff) is determined as a function of a motor torque and an efficiency, the efficiency being determined as a function of the estimated force (Fz).

Abstract: So as to provide, with high accuracy, an actuating variable for actuating a torque control element in an electric vehicle steering system and achieve this with reduced complexity as compared to the known methods and devices, an actual torsion-bar torque (MD) is detected, a differential torque is found from a predefined target torsion-bar torque (MD,ref) and the actual torsion-bar torque (MD), and the actuating variable is determined by means of an output feedback controller, as a function of the differential torque.

Abstract: Provided is a way of using an estimator to determine a force (Fz), which acts from the outside on a steering gear of a steering device in a vehicle by way of a steering linkage, wherein a motor for generating a steering torque is assigned to the steering device. This is achieved by estimating the force (Fz) acting from the outside as a function of an effective motor torque (tor_RAeff), wherein the effective motor torque (tor_RAeff) is determined as a function of a motor torque and an efficiency, the efficiency being determined as a function of the estimated force (Fz).

Abstract: So as to provide, with high accuracy, an actuating variable for actuating a torque control element in an electric vehicle steering system and achieve this with reduced complexity as compared to the known methods and devices, an actual torsion-bar torque (MD) is detected, a differential torque is found from a predefined target torsion-bar torque (MD,ref) and the actual torsion-bar torque (MD), and the actuating variable is determined by means of an output feedback controller, as a function of the differential torque.

Abstract: A method is disclosed for operating a power steering system in which a motor torque is computed by an electronic processor and established by suitable motor actuation, wherein a plausibility check is carried out for the computed motor torque as part of a 3-level design, wherein integration of a part above a motor torque limit curve and decrementation of an integrator with a part below the motor torque limit curve are performed, the target motor torque being limited to a first integration threshold in level 1, and the limitation is monitored in level 2, with an intrinsically safe motor torque limit curve being used as a function of an actual torque.