Patents by Inventor Stefan Hafner

Stefan Hafner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9109200
    Abstract: The invention relates to the use of an enzyme preparation which catalyzes the degradation of formaldehyde for reducing the formaldehyde content in a formaldehyde-containing formulation. In a preferred embodiment, the enzyme preparation contains a formaldehyde dismutase from a Pseudomonas putida strain. Further, the invention refers to a process for reducing the formaldehyde content in cross-linking agents for textile finishing or in polymer dispersions used, e.g. in construction chemistry. Further the invention relates to the use of an enzyme preparation which catalyzes the degradation of aldehydes for reducing the formaldehyde content in an aldehyde-containing formulation. Furthermore, the invention relates to a novel variant of the formaldehyde dismutase from Pseudomonas putida.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: August 18, 2015
    Assignee: BASF SE
    Inventors: Andrea Piatesi, Tilo Habicher, Michael Büschel, Li-Wen Wang, Jürgen Reichert, Rainer Packe-Wirth, Kai-Uwe Baldenius, Erich Kromm, Stefan Häfner, Carsten Schwalb, Hans Wolfgang Höffken
  • Publication number: 20120028333
    Abstract: The invention relates to the use of an enzyme preparation which catalyzes the degradation of formaldehyde for reducing the formaldehyde content in a formaldehyde-containing formulation. In a preferred embodiment, the enzyme preparation contains a formaldehyde dismutase from a Pseudomonas putida strain. Further, the invention refers to a process for reducing the formaldehyde content in cross-linking agents for textile finishing or in polymer dispersions used, e.g. in construction chemistry. Further the invention relates to the use of an enzyme preparation which catalyzes the degradation of aldehydes for reducing the formaldehyde content in an aldehyde-containing formulation. Furthermore, the invention relates to a novel variant of the formaldehyde dismutase from Pseudomonas putida.
    Type: Application
    Filed: March 31, 2010
    Publication date: February 2, 2012
    Inventors: Andrea Piatesi, Tilo Habicher, Michael Büschel, Li-Wen Wang, Jürgen Reichert, Rainer Packe-Wirth, Kai-Uwe Baldenius, Erich Kromm, Stefan Häfner, Carsten Schwalb, Hans Wolfgang Höffken
  • Publication number: 20100015674
    Abstract: The present invention features methods of increasing the production of a fine chemical, e.g., lysine from a microorganism, e.g., Corynebacterium by way of deregulating an enzyme encoding gene, i.e., fructose-1,6-bisphosphatase. In a preferred embodiment, the invention provides methods of increasing the production of lysine in Corynebacterium glutamicum by way of increasing the expression of fructose-1,6-bisphosphatase activity. The invention also provides a novel process for the production of lysine by way of regulating carbon flux towards oxaloacetate (OAA). In a preferred embodiment, the invention provides methods for the production of lysine by way of utilizing fructose or sucrose as a carbon source.
    Type: Application
    Filed: July 31, 2009
    Publication date: January 21, 2010
    Applicant: BASF SE
    Inventors: Oskar Zelder, Corinna Klopprogge, Hartwig Schroder, Stefan Häfner, Burkhard Kröger, Patrick Kiefer, Elmar Heinzle, Christoph Wittmann
  • Patent number: 7635580
    Abstract: The invention relates to methods for the production of sulfur-containing fine chemicals, in particular L-methionine, by fermentation using bacteria in which a nucleotide sequence encoding an S-adenosylmethionine synthase (metK) gene is expressed.
    Type: Grant
    Filed: May 23, 2003
    Date of Patent: December 22, 2009
    Assignee: Evonik Degussa GmbH
    Inventors: Hartwig Schröder, Burkhard Kröger, Oskar Zelder, Corinna Klopprogge, Stefan Häfner
  • Patent number: 7485444
    Abstract: The invention relates to methods for the fermentative production of sulfur-containing fine chemicals, in particular L-methionine, by using bacteria which express a nucleotide sequence coding for a methionine synthase (metH) gene.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: February 3, 2009
    Assignee: Evonik Degussa GmbH
    Inventors: Burkhard Kröger, Oskar Zelder, Corinna Klopprogge, Hartwig Schröder, Stefan Häfner
  • Publication number: 20080280333
    Abstract: Isolated polypeptide sequence having the sequence of SEQ ID NO:1 or muteins thereof having the ability to bind cAMP and repress the expression of the aceB gene of C. glutamicum and which can be obtained from SEQ ID NO:1 by inserting, deleting or substituting up to 20% of the amino acids.
    Type: Application
    Filed: February 8, 2007
    Publication date: November 13, 2008
    Applicant: BASF AG
    Inventors: Corinna Klopprogge, Oskar Zelder, Burkhard Kroger, Hartwig Schroder, Stefan Hafner, Heung-Shick Lee
  • Patent number: 7448465
    Abstract: An industrial truck has a steering axle with two axle tree bolster systems located at a lateral distance from each other. Each system has an axle body with an axle shaft (1) and an axle tree bolster (2) located on the lower end of the axle shaft (1). The axle tree bolster (2) and the axle shaft (1) are individual components that are connected with each other. The axle tree bolster (2) is preferably detachably fastened to the axle shaft (1). The rotational position of the axle tree bolster (2) relative to the axle shaft (1) can be adjustable. Means can also be provided for the positive and/or non-positive transmission of a torque from the axle shaft (1) to the axle tree bolsters (2).
    Type: Grant
    Filed: November 11, 2005
    Date of Patent: November 11, 2008
    Assignee: Linde Material Handling GmbH
    Inventors: Bernhard Götz, Stefan Hafner, Constantin Roβkopf
  • Publication number: 20080166774
    Abstract: The invention relates to a method for producing an amino acid comprising culturing a microorganism of the genus Corynebacterium or Brevibacterium wherein said microorganism is partially or completely deficient in at least one of the gene loci of the group which is formed by otsAB, treZ and treS, and subsequent isolation of the amino acid from the culture medium.
    Type: Application
    Filed: January 28, 2008
    Publication date: July 10, 2008
    Applicant: BASF AG
    Inventors: Corinna Klopprogge, Oskar Zelder, Burkhard Kroger, Hartwig Schroder, Stefan Hafner, Wolfgang Liebl
  • Publication number: 20080160585
    Abstract: The present invention features methods of increasing the production of a fine chemical, e.g., lysine from a microorganism, e.g., Corynebacterium by way of deregulating an enzyme encoding gene, i.e., fructose-1,6-bisphosphatase. In a preferred embodiment, the invention provides methods of increasing the production of lysine in Corynebacterium glutamicum by way of increasing the expression of fructose-1,6-bisphosphatase activity. The invention also provides a novel process for the production of lysine by way of regulating carbon flux towards oxaloacetate (OAA). In a preferred embodiment, the invention provides methods for the production of lysine by way of utilizing fructose or sucrose as a carbon source.
    Type: Application
    Filed: January 28, 2008
    Publication date: July 3, 2008
    Applicant: BASF Aktiengesellschaft
    Inventors: Oskar Zelder, Corinna Klopprogge, Hartwig Schroder, Stefan Hafner, Burkhard Kroger, Patrick Kiefer, Elmar Heinzle, Christoph Wittmann
  • Patent number: 7381549
    Abstract: The invention relates to methods for the fermentative production of sulfur-containing fine chemicals, in particular L-methionine, by using bacteria which express a nucleotide sequence coding for a methionine synthase (metH) gene.
    Type: Grant
    Filed: August 26, 2003
    Date of Patent: June 3, 2008
    Assignee: BASF Aktiengesellschaft
    Inventors: Burkhard Kröger, Oskar Zelder, Corinna Klopprogge, Hartwig Schröder, Stefan Häfner
  • Publication number: 20080118959
    Abstract: The invention relates to methods for the production of sulfur-containing fine chemicals, in particular L-methionine, by fermentation using bacteria in which a nucleotide sequence encoding an S-adenosylmethionine synthase (metK) gene is expressed.
    Type: Application
    Filed: May 23, 2003
    Publication date: May 22, 2008
    Inventors: Hartwig Schroder, Burkhard Kroger, Oskar Zelder, Corinna Klopprogge, Stefan Hafner
  • Publication number: 20080038787
    Abstract: The present invention features methods of increasing the production of a fine chemical, e.g., lysine from a microorganism, e.g., Corynebacterium by way of deregulating an enzyme encoding gene, i. e., glycerol kinase. In a preferred embodiment, the invention provides methods of increasing the production of lysine in Corynebacterium glutamicum by way of increasing the expression of glycerol kinase activity. The invention also provides a novel process for the production of lysine by way of regulating carbon flux towards oxaloacetate (OAA). In a preferred embodiment, the invention provides methods for the production of lysine by way of utilizing fructose or sucrose as a carbon source.
    Type: Application
    Filed: December 17, 2004
    Publication date: February 14, 2008
    Applicant: Basf Aktiengesellschaft
    Inventors: Oskar Zelder, Corinna Klopprogge, Hartwig Schroder, Stefan Hafner, Burkhard Kroger, Patrick Kiefer, Elmar Heinzle, Christoph Wittmann
  • Publication number: 20080032374
    Abstract: The present invention features methods of increasing the production of a fine chemical, e.g., lysine from a microorganism, e.g., Corynebacterium by way of deregulating an enzyme encoding gene, i.e., fructose-1,6-bisphosphatase. In a preferred embodiment, the invention provides methods of increasing the production of lysine in Corynebacterium glutamicum by way of increasing the expression of fructose-1,6-bisphosphatase activity. The invention also provides a novel process for the production of lysine by way of regulating carbon flux towards oxaloacetate (OAA). In a preferred embodiment, the invention provides methods for the production of lysine by way of utilizing fructose or sucrose as a carbon source.
    Type: Application
    Filed: December 17, 2004
    Publication date: February 7, 2008
    Applicant: Basf Aktiengesellschaft
    Inventors: Oskar Zelder, Corinna Klopprogge, Hartwig Schroder, Stefan Hafner, Burkhard Kroger, Patrick Kiefer, Elmar Heinzle, Christoph Wittmann
  • Patent number: 7282357
    Abstract: The invention relates to methods for the fermentative production of sulfur-containing fine chemicals, in particular L-methionine, by using bacteria which express a nucleotide sequence coding for a methionine synthase (metF) gene.
    Type: Grant
    Filed: August 26, 2003
    Date of Patent: October 16, 2007
    Assignee: BASF Aktiengesellschaft
    Inventors: Burkhard Kröger, Oskar Zelder, Corinna Kolpprogge, Hartwig Schröder, Stefan Häfner
  • Patent number: 7238502
    Abstract: The invention relates to methods for the fermentative production of sulfur-containing fine chemicals, in particular L-methionine, by using bacteria which express a nucleotide sequence coding for a methionine synthase (metA) gene.
    Type: Grant
    Filed: August 26, 2003
    Date of Patent: July 3, 2007
    Assignee: BASF Aktiengesellschaft
    Inventors: Burkhard Kröger, Oskar Zelder, Corinna Kolpprogge, Hartwig Schröder, Stefan Häfner
  • Publication number: 20070134768
    Abstract: The present invention features methods of increasing the production of a fine chemical, e.g., lysine from a microorganism, e.g., Corynebacterium by way of deregulating an enzyme encoding gene, i.e., lactate dehydrogenase. In a preferred embodiment, the invention provides methods of increasing the production of lysine in Corynebacterium glutamicum by way of the expression of lactate dehydrogenase activity. The invention also provides a novel process for the production of lysine by way of regulating carbon flux towards oxaloacetate (OAA). In a preferred embodiment, the invention provides methods for the production of lysine by way of utilizing fructose or sucrose as a carbon source.
    Type: Application
    Filed: December 17, 2004
    Publication date: June 14, 2007
    Applicant: BASF Aktiengesellschaft
    Inventors: Oskar Zelder, Corinna Klopprogge, Hartwig Schroder, Stefan Hafner, Burkhard Kroger, Patrick Kiefer, Elmar Heinzle, Christoph Wittmann
  • Patent number: 7192749
    Abstract: Isolated polypeptide sequence having the sequence of SEQ ID NO:1 or muteins thereof having the ability to bind cAMP and repress the expression of the aceB gene of C. glutamicum and which can be obtained from SEQ ID NO:1 by inserting, deleting or substituting up to 20% of the amino acids.
    Type: Grant
    Filed: May 13, 2003
    Date of Patent: March 20, 2007
    Assignee: BASF Aktiengesellschaft
    Inventors: Corinna Klopprogge, Oskar Zelder, Burkhard Kröger, Hartwig Schröder, Stefan Häfner, Heung-Shick Lee
  • Publication number: 20060223149
    Abstract: The invention relates to methods for the fermentative production of sulfur-containing fine chemicals, in particular L-methionine, by using bacteria which express a nucleotide sequence coding for a methionine synthase (metH) gene.
    Type: Application
    Filed: April 16, 2003
    Publication date: October 5, 2006
    Inventors: Burkhard Kröger, Oskar Zelder, Corinna Klopprogge, Hartwig Schröder, Stefan Häfner
  • Publication number: 20060156946
    Abstract: An industrial truck has a steering axle with two axle tree bolster systems located at a lateral distance from each other. Each system has an axle body with an axle shaft (1) and an axle tree bolster (2) located on the lower end of the axle shaft (1). The axle tree bolster (2) and the axle shaft (1) are individual components that are connected with each other. The axle tree bolster (2) is preferably detachably fastened to the axle shaft (1). The rotational position of the axle tree bolster (2) relative to the axle shaft (1) can be adjustable. Means can also be provided for the positive and/or non-positive transmission of a torque from the axle shaft (1) to the axle tree bolsters (2).
    Type: Application
    Filed: November 11, 2005
    Publication date: July 20, 2006
    Applicant: Linde Aktiengesellschaft
    Inventors: Bernhard Gotz, Stefan Hafner, Constantin Rosskopf
  • Publication number: 20060068476
    Abstract: The invention relates to methods for the fermentative production of sulfur-containing fine chemicals, in particular L-methionine, by using bacteria which express a nucleotide sequence coding for a methionine synthase (metF) gene.
    Type: Application
    Filed: August 26, 2003
    Publication date: March 30, 2006
    Inventors: Burkhard Kroger, Oskar Zelder, Corinna Klopprogge, Hartwig Schroder, Stefan Hafner