Abstract: The invention relates to a liquid separator for separating liquid from a gas-liquid mixture, having a housing, an inlet, an outlet, a flow path connecting the inlet to the outlet, and a separating device, arranged in the flow path, for liquid separation, wherein a wall body is attached to the inner side of a housing portion adjoining the outlet, surrounds an annular collar projecting into the housing from the outlet, and extends towards a liquid outlet, wherein the wall body, together with a wall of the housing, defines a flow channel so that liquid collected at the outlet can be discharged through the flow channel via the liquid outlet.

Abstract: A method and a device for the production of polyamide 6 pellets wherein an intermediate drying is not necessary and a combined pelletizing and extraction take place. Depending on the intended use, the pellets may directly be used or subjected to further treatment steps. A device for the production of polyamide 6 pellets includes a melt device for providing a melt of polyamide 6, an underwater pelletizing system which is operable under increased pressure, and a vertical vessel having a cylindrical section and a tapered bottom section. The tapered bottom section is provided with a cooling device and is connected to a pipe comprising a screw and/or a rotary gate valve for conveying pellets. The device includes a circuit for circulating an aqueous solution of ? caprolactam through the underwater pelletizing system and the vertical vessel.

Abstract: The present invention provides a combination therapy for effectively treating and/or preventing diseases associated with cells expressing CLDN18.2, including cancer diseases such as pancreatic cancer and metastases thereof.

Abstract: A drum brake for a motor vehicle has a pocket for collecting abraded brake particles. The pocket is accessible from above via an opening. After the introduction of a suction device into the opening, the abraded brake particles can be extracted by suction. Pollution of the environment with abraded brake particles is thereby avoided.

Abstract: A liquid separator (10) for separating liquid from a gas-liquid mixture has a housing (12), an inlet (14), an outlet (16), a flow path (18) connecting the inlet (14) to the outlet (16), and a separation device (20), arranged in the flow path (18), for liquid separation, wherein a diverting element (22) is arranged adjacent to the separation device (20). Said diverting element separates an inlet region (24) of the housing (12), into which the inlet (14) opens, and an outlet region (26) of the housing (12), from which the outlet (16) opens, from one another, wherein the flow path (18) extends from the inlet region (24) via a low-flow region (46) into the outlet region (26).

Abstract: The present invention is directed to a method for modifying the retention time of RNA on a chromatographic column. The present invention also concerns a method for purifying RNA from a mixture of at least two RNA species. Furthermore, the present invention relates to a method for co-purifying at least two RNA species from a mixture of at least two RNA species. In particular, the present invention provides a method for harmonizing the numbers of A and/or U nucleotides in at least two RNA species. The present invention is also directed to RNA obtainable by said methods, a composition comprising said RNA or a vaccine comprising said RNA and methods for producing such RNA and compositions. Further, the invention concerns a kit, particularly a kit of parts, comprising the RNA, composition or vaccine. The invention is further directed to a method of treating or preventing a disorder or a disease, first and second medical uses of the RNA, composition and vaccine.

Abstract: The invention relates to an industrial process controller comprising at least three field devices coupled to one another by means of a data link, with the field devices controlling and/or monitoring an industrial process, wherein the field devices are configured to store a block chain, wherein the block chain comprises a plurality of blocks, and wherein the blocks store use data. The process controller is characterized in that the field devices are configured to delete one or more blocks from the block chain and to adapt the block chain to the change caused by the deletion.

Abstract: The present invention relates to a method for quality control analysis of an RNA sample comprising n different RNA molecule species using reverse transcription and a polymerase chain reaction (PCR) based assay, dPCR, preferably ddPCR, thereby determining at least one quality parameter. Moreover, the RNA molecules in the RNA sample may be in complexed form. In particular, the method is suitable for use in quality control during or following production of RNA samples for pharmaceutical use.

Abstract: A drum brake for a motor vehicle has a pocket for collecting abraded brake particles. The pocket is accessible from above via an opening. After the introduction of a suction device into the opening, the abraded brake particles can be extracted by suction. Pollution of the environment with abraded brake particles is thereby avoided.

Abstract: A liquid separator for separating liquid out of a gas/liquid mixture, including an inlet, an outlet, a flow path connecting the inlet to the outlet and at least one separating device arranged in the flow path, the liquid separator being designed and embodied with simple structure and a compact construction to enable reliable separation of liquids in such a way that the separating device has a fabric portion for liquid separation through which the flow path passes, the fabric portion being arranged at an angle of 1° to 15° relative to the main flow direction in the separating device.

Abstract: Method for bending a plastic pipe including arranging a bending portion of a plastic pipe in a heating zone of a heater and performing contactless local heating of the bending portion, wherein the heater is adapted to provide a first predetermined temperature difference between a neutral zone of the bending portion and a compression zone of the bending portion and a second predetermined temperature difference between the neutral zone and the compression zone of the bending area and an expansion zone of the bending area, introducing bending forces on holding regions arranged on the plastic pipe at a distance from the bending area and/or introducing bending forces on the bending area for deforming the plastic pipe into a deformation position and cooling the plastic pipe in the deformation position.

Abstract: The present invention is directed to a method for modifying the retention time of RNA on a chromatographic column. The present invention also concerns a method for purifying RNA from a mixture of at least two RNA species. Furthermore, the present invention relates to a method for co-purifying at least two RNA species from a mixture of at least two RNA species. In particular, the present invention provides a method for harmonizing the numbers of A and/or U nucleotides in at least two RNA species. The present invention is also directed to RNA obtainable by said methods, a composition comprising said RNA or a vaccine comprising said RNA and methods for producing such RNA and compositions. Further, the invention concerns a kit, particularly a kit of parts, comprising the RNA, composition or vaccine. The invention is further directed to a method of treating or preventing a disorder or a disease, first and second medical uses of the RNA, composition and vaccine.

Abstract: The present invention is concerned with methods for analyzing RNA molecules. The provided methods involve conjugates for RNA cleavage comprising a chemical moiety with RNA cleaving activity and an oligonucleotide. The oligonucleotide is designed based on a target sequence present in an RNA molecule, and the cleavage of the RNA molecule is inter alia carried out at conditions allowing the hybridization of the oligonucleotide to the target 5 sequence. Thereby, the method is easily applicable to RNA molecules of any sequence. The method further involves the analysis of the RNA fragments obtained after cleavage to obtain information on the physical properties of the RNA molecule.

Abstract: Method for bending a plastic pipe including arranging a bending portion of a plastic pipe in a heating zone of a heater and performing contactless local heating of the bending portion, wherein the heater is adapted to provide a first predetermined temperature difference between a neutral zone of the bending portion and a compression zone of the bending portion and a second predetermined temperature difference between the neutral zone and the compression zone, of the bending area and an expansion zone of the bending area, introducing bending forces on holding regions arranged on the plastic pipe at a distance from the bending area and/or introducing bending forces on the bending area for deforming the plastic pipe into a deformation position and cooling the plastic pipe in the deformation position.

Abstract: The invention relates to an industrial process controller comprising at least three field devices coupled to one another by means of a data link, with the field devices controlling and/or monitoring an industrial process, wherein the field devices are configured to store a block chain, wherein the block chain comprises a plurality of blocks, and wherein the blocks store use data. The process controller is characterized in that the field devices are configured to delete one or more blocks from the block chain and to adapt the block chain to the change caused by the deletion.

Abstract: Described is a method for producing a stator, in particular for electric motors. In a first step, a plurality of flexible electrical conductors are combined to form a conductor bundle. In a second step, two end regions of the conductor bundle are pressed in such a way that a central region of the conductor bundle formed between the two end regions remains flexible. Also described is a corresponding stator.

Abstract: A novel, particularly rationally designed, modular parking brake actuator for an electric drum brake system. An axle A1 from the motor, including a screw gear pinion coupled in a rotationally fixed manner, and an axle of the spindle arrangement, including a screw gear which is coupled in a rotationally fixed manner to the drive nut, define under a deflection of 90° a single wheel gearbox stage of the parking brake actuator.

Abstract: A novel, particularly rationally designed, modular parking brake actuator for an electric drum brake system. An axle A1 from the motor, including a screw gear pinion coupled in a rotationally fixed manner, and an axle A2 of the spindle arrangement, including a screw gear which is coupled in a rotationally fixed manner to the drive nut, define under a deflection of 90° a single wheel gearbox stage of the parking brake actuator.

Abstract: Described is a method for producing a stator, in particular for electric motors. In a first step, a plurality of flexible electrical conductors are combined to form a conductor bundle. In a second step, two end regions of the conductor bundle are pressed in such a way that a central region of the conductor bundle formed between the two end regions remains flexible. Also described is a corresponding stator.

Abstract: The invention relates to an oil filter arrangement having a housing comprising a receiving space for a filter element, wherein a discharge opening is provided at the bottom of the receiving space and a discharge valve is provided in the discharge opening wherein the discharge valve comprises a valve body, which is movable between a closing position and an opening position in a displaceable manner and is moved to the locking position by a first spring element when the filter element is inserted, wherein the first spring element is disposed on the valve body on the side of the valve body facing away from the discharge opening and is configured as a compound spring having a flat, bent metal band. The metal band acts against the filter element or against an end disk of the filter element when the filter element is inserted.