Patents by Inventor Stefan Henke
Stefan Henke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20130307403Abstract: A spark plug with a particular configuration, particularly in the area of a gasket that seals between a shell and insulator, increases the mechanical strength of the spark plug and helps prevent breaking, cracking and/or other failures in the insulator. The spark plug is designed such that the shell, insulator and gasket, which may be in the form of a sleeve-like cylindrical gasket or a ring-like annular gasket, work together to provide better support for the insulator against axial and/or radial stresses. This improved support can offset certain stresses, such as radial stress RS that can be exerted against the insulator core nose when the engine experiences knocking or misfiring.Type: ApplicationFiled: May 9, 2013Publication date: November 21, 2013Inventor: Stefan Henke
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Publication number: 20130177613Abstract: A packaging assembly or kit includes packaging material containing a solid formulation including pimobendan dispersed in a polyvalent acid. The kit may also include a package leaflet or user instruction including the information concerning use of the solid formulation, for example, via the oral route for the prevention and/or treatment of congestive heart failure in a mammal in need of such prevention or treatment, preferably in a dog, cat or rodent.Type: ApplicationFiled: March 14, 2013Publication date: July 11, 2013Applicant: BOEHRINGER INGELHEIM VETMEDICA GMBHInventors: Martin A. Folger, Bernhard Hassel, Stefan Henke, Jens Lehmann (nee Schmalz)
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Publication number: 20130178467Abstract: Aqueous cyclodextrin-free solution of meloxicam for administration by oral or parenteral route, containing a pharmacologically acceptable meloxicam salt of an organic or inorganic base and one or more suitable excipients, the content of dissolved meloxicam salt being more than 10 mg/mL. The formulation according to the invention has a shelf-life of up to 24 months or more.Type: ApplicationFiled: March 14, 2013Publication date: July 11, 2013Applicant: BOEHRINGER INGELHEIM VETMEDICA GMBHInventors: Stefan Henke, Bernd Kruss, Bernhard Hassel, Hans-Juergen Kroff, Martin A. Folger, Klaus Daneck, Axel Prox
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Publication number: 20130005714Abstract: Water soluble meloxicam granules comprising: (a) meloxicam; (b) a salt forming agent which forms the meglumine, sodium, potassium, or ammonium salt of meloxicam; (c) a binder; (d) a sugar or sweetener; and (e) a carrier, and optionally a flavoring agent and optionally other excipients, processes for preparing them and their use for treating respiratory or inflammatory complaints in mammals.Type: ApplicationFiled: September 5, 2012Publication date: January 3, 2013Applicant: BOEHRINGER INGELHEIM VETMEDICA GMBHInventors: Stefan HENKE, Martin Andreas FOLGER, Jens SCHMALZ, Diana KEILHOFER, Hans-Juergen KROFF, Nina HERZ
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Patent number: 8273952Abstract: The present invention relates generally to the field of molecular biology and concerns a method for improving plant growth characteristics. More specifically, the present invention concerns a method for improving plant growth characteristics by modulating expression in a plant of a plant nucleic acid encoding a cyclin dependent kinase (CDK) and/or by modulating activity in a plant of a plant CDK protein, which CDK protein comprises different motifs or which CDK nucleic acid encodes such protein. The present invention also concerns plants having modulated expression of a plant CDK nucleic acid and/or modulated activity of a plant CDK protein, which CDK protein comprises different sequence motifs or which nucleic acid encodes such protein and which plants have improved growth characteristics relative to corresponding wild type plants.Type: GrantFiled: May 31, 2007Date of Patent: September 25, 2012Assignee: BASF Plant Science GmbHInventors: Stefan Henkes, Christian Dammann
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Publication number: 20120227134Abstract: A method for producing a plant with increased yield as compared to a corresponding wild type plant whereby the method comprises at least the following step: increasing or generating in a plant or a part thereof one or more activities of a polypeptide selected from the group consisting of 2-oxoglutarate-dependent dioxygenase, 3-ketoacyl-CoA thiolase, 3?-phosphoadenosine 5?-phosphate phosphatase, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, 5OS chloroplast ribosomal protein L21, 57972199. R01.1-protein, 60952769. R01.1-protein, 60S ribosomal protein, ABC transporter family protein, AP2 domain-containing transcription factor, argonaute protein, AT1 G29250.Type: ApplicationFiled: November 5, 2010Publication date: September 6, 2012Applicant: BASF PLANT SCIENCE COMPANY GMBHInventors: Hardy Schön, Oliver Thimm, Gerhard Ritte, Oliver Bläsing, Stefan Henkes, Koen Bruynseels, Yves Hatzfeld, Valerie Frankard, Ana Isabel Sanz Molinero, Christophe Reuzeau, Steven Vandenabeele, Bryan McKersie, Krishna Kolliparra, Christian Dammann
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Publication number: 20120148640Abstract: The invention relates to novel solid formulations comprising as pharmaceutically active compound pimobendan and to processes for producing such solid formulations. The invention furthermore relates to a method for manufacturing a medicament for the prevention and/or treatment of congestive heart failure, wherein the solid formulations according to the invention are used.Type: ApplicationFiled: February 22, 2012Publication date: June 14, 2012Applicant: BOEHRINGER INGELHEIM VETMEDICA GMBHInventors: Martin A. Folger, Bernhard Hassel, Stefan Henke, Jens Schmalz
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Patent number: 7951991Abstract: The invention provides polynucleotides encoding plant prenyl protease polypeptides, vectors, host cells, and transgenic plant comprising the polynucleotides. The invention also provides methods of producing transgenic plants that have altered levels of prenyl protease polynucleotides and polypeptides, and transgenic plants that have increased tolerance to an environmental stress as compared to a wild type plant.Type: GrantFiled: July 17, 2007Date of Patent: May 31, 2011Assignees: BASF Plant Science GmbH, Performance Plants, Inc.Inventors: Rodrigo Sarria-Millan, Stefan Henkes, Damian Allen, Oswaldo da Costa e Silva, Ruoying Chen, Jiangxin Wan, Yafan Huang, Delina Mary-Jane Melo, Monika Maria Kuzma, Angela Patricia Gilley Sample
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Publication number: 20110098183Abstract: This invention relates generally to plant cells and/or plants with increased tolerance to environmental stress and/or increased yield as compared to a corresponding, e.g. non-transformed, wild type plant cell by increasing or generating one or more activities of polypeptides associated with abiotic stress responses and abiotic stress tolerance in plants. In particular, this invention relates to plant cells and/or plants tailored to grow under conditions of environmental stress, and/or to plant cells and/or plant showing increased yield under environmental stress conditions. The invention also deals with methods of producing and screening for and breeding such plant cells and/or plants.Type: ApplicationFiled: December 19, 2008Publication date: April 28, 2011Applicant: BASF Plant Science GmbHInventors: Oliver Bläsing, Oliver Thimm, Stefan Henkes, Bruce Wesley, Resham Kulkarni, Krishna Kollipara, Christophe Reuzeau
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Publication number: 20100229259Abstract: The present invention relates generally to the field of molecular biology and concerns a method for improving plant growth characteristics. More specifically, the present invention concerns a method for improving plant growth characteristics by modulating expression in a plant of a plant nucleic acid encoding a cyclin dependent kinase (CDK) and/or by modulating activity in a plant of a plant CDK protein, which CDK protein comprises different motifs or which CDK nucleic acid encodes such protein. The present invention also concerns plants having modulated expression of a plant CDK nucleic acid and/or modulated activity of a plant CDK protein, which CDK protein comprises different sequence motifs or which nucleic acid encodes such protein and which plants have improved growth characteristics relative to corresponding wild type plants.Type: ApplicationFiled: May 31, 2007Publication date: September 9, 2010Applicant: BASF Plant Science GmbHInventors: Stefan Henkes, Christian Dammann
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Patent number: 7722093Abstract: The invention relates to a fitting for connecting lengths of pipe by compression, having a substantially cylindrical internal contour. The fitting has a ridge which is configured in a radially outward direction and in which a sealing element is provided. The fitting is slidable onto the lengths of pipe, the internal contour having a region of non-circular cross-section. The invention also relates to a connecting arrangement for connecting lengths of pipe by compression, comprising a length of pipe and a fitting plus a sealing element which is arranged in the ridge. One axial gap which extends over the entire connecting region is formed between the length of pipe and the internal contour of the fitting in the uncompressed state. Such an axial gap with an open end would ensure that a leak exists even in the region of the sealing element in an uncompressed state.Type: GrantFiled: June 24, 2005Date of Patent: May 25, 2010Assignee: Yorkshire Fittings Ltd.Inventor: Stefan Henke
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Publication number: 20100065444Abstract: The invention relates to a pack comprising a packaging material and soft capsules, to a process for the stabilisation of soft capsules, and to a process for the production of the pack.Type: ApplicationFiled: December 10, 2007Publication date: March 18, 2010Inventors: Stefan Henke, Holger Peitz
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Publication number: 20090314664Abstract: The invention relates to a pack comprising a container (2) and solid pharmaceutical administration forms packed in blister packs (4).Type: ApplicationFiled: July 4, 2007Publication date: December 24, 2009Applicant: MERCK PATENT GMBHInventors: Stefan Henke, Peitz Holger
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Publication number: 20090162322Abstract: The invention relates to an oral administration form which comprises at least one species of probiotic microorganisms, where it itself and/or the probiotic bacteria is/are provided with a coating which comprises at least two cellulose ethers.Type: ApplicationFiled: May 4, 2005Publication date: June 25, 2009Inventors: Markus Rudolph, Stefan Henke, Iris Manneck
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Patent number: 7473819Abstract: A transgenic plant transformed by a protein kinase stress-related protein (PKSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased tolerance to environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic plants. Also provided are isolated PKSRP, and isolated nucleic acid coding PKSRP, and vectors and host cells containing the latter. Further provided are methods of producing transgenic plants expressing PKSRP, and methods of identifying novel PKSRP and methods of modifying the expression of PKSRP in plants.Type: GrantFiled: December 20, 2007Date of Patent: January 6, 2009Assignee: BASF Plant Science GmbhInventors: Oswaldo da Costa e Silva, Manabu Ishitani, Stefan Henkes, Nocha van Thielen, Ruoying Chen
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Patent number: 7425665Abstract: A transgenic plant transformed by a protein kinase stress-related protein (PKSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased tolerance to environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic plants. Also provided are isolated PKSRP, and isolated nucleic acid coding PKSRP, and vectors and host cells containing the latter. Further provided are methods of producing transgenic plants expressing PKSRP, and methods of identifying novel PKSRP and methods of modifying the expression of PKSRP in plants.Type: GrantFiled: January 10, 2007Date of Patent: September 16, 2008Assignee: BASF Plant Science GmbHInventors: Oswaldo da Costa e Silva, Manabu Ishitani, Stefan Henkes, Nocha van Thielen, Ruoying Chen
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Publication number: 20080219961Abstract: The invention relates to a method for stabilising solid pharmaceutical administration forms which comprises at least one species of microorganism, and to a pack comprising packaging and a solid pharmaceutical administration form which comprises at least one species of microorganism.Type: ApplicationFiled: August 30, 2006Publication date: September 11, 2008Applicant: MERCK PATENT GMBHInventors: Markus Rudolph, Stefan Henke, Iris Manneck, Holger Peitz, Andrea Christ
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Publication number: 20080178356Abstract: A transgenic plant transformed by a protein kinase stress-related protein (PKSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased tolerance to environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic plants. Also provided are isolated PKSRP, and isolated nucleic acid coding PKSRP, and vectors and host cells containing the latter. Further provided are methods of producing transgenic plants expressing PKSRP, and methods of identifying novel PKSRP and methods of modifying the expression of PKSRP in plants.Type: ApplicationFiled: December 20, 2007Publication date: July 24, 2008Applicant: BASF Plant Science GmbHInventors: Oswaldo da Costa e Silva, Manabu Ishitani, Stefan Henkes, Nocha Van Thielen, Ruoying Chen
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Publication number: 20080132493Abstract: Aqueous cyclodextrin-free solution of meloxicam suitable for administration by needleless injection, containing a pharmacologically acceptable meloxicam salt of an organic or inorganic base and one or more suitable excipients, the content of dissolved meloxicam salt being from 35 to 100 mg/ml. The formulation according to the invention has a shelf-life of up to 24 months or more.Type: ApplicationFiled: August 27, 2007Publication date: June 5, 2008Inventors: Martin Andreas Folger, Stefan Henke, Bernhard Hassel, Bernd Zierenberg
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Publication number: 20080072350Abstract: The present invention provides novel polynucleotides encoding plant prenyl protease polypeptides, fragments and homologs thereof. Also provided are vectors, host cells, and recombinant methods for producing said polypeptides. The invention further provides novel polynucleotides encoding plant promoters, polypeptides, fragments and homologs thereof. The invention additionally provides methods of constructing transgenic plants that have altered levels of prenyl protease polynucleotides and polypeptides. Methods for identifying prenyl protease enzymes substrates and inhibitors are also provided. The invention further relates to methods of applying these novel plant polypeptides to the identification, prevention, and/or conferment of resistance to various plant diseases and/or disorders, particularly drought resistance.Type: ApplicationFiled: July 17, 2007Publication date: March 20, 2008Applicants: BASF Plant Science GmbH, Performance Plants, Inc.Inventors: Rodrigo Sarria-Millan, Stefan Henkes, Damian Allen, Oswaldo da Costa e Silva, Ruoying Chen, Jiangxin Wan, Yafan Huang, Delina Melo, Monika Kuzma, Angela Gilley Sample