Patents by Inventor Stefan Jaroch

Stefan Jaroch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzoxazine and benzothiazine derivatives and their use in medicines
    Patent number: 6841550
    Abstract: The invention relates to compounds of formula (I) and their tautomeric and isomeric forms and salts, as well as to a method for producing said compounds and their use in medicines.
    Type: Grant
    Filed: September 16, 1999
    Date of Patent: January 11, 2005
    Assignee: Schering Aktiengesellschaft
    Inventors: Peter Hölscher, Hartmut Rehwinkel, Stefan Jaroch, Detlev Sülzle, Margrit Hillmann, Gerardine Anne Burton, Fiona Mcdougall McDonald
  • Nonsteroidal antiinflammatory agents
    Publication number: 20040254249
    Abstract: Compounds of Formula 1 1
    Type: Application
    Filed: June 24, 2004
    Publication date: December 16, 2004
    Inventors: Stefan Jaroch, Manfred Lehmann, Norbert Schmees, Bernd Buchmann, Harmur Rehwinkel, Peter Droescher, Werner Skuballa, Konrad Krolikiewicz, Hartwig Hennekes, Heike Schaecke, Arndr Schottelius
  • Nonsteroidal antiinflammatory agents
    Publication number: 20040209875
    Abstract: The invention relates to compounds of general formula I 1
    Type: Application
    Filed: December 19, 2003
    Publication date: October 21, 2004
    Inventors: Norbert Schmees, Manfred Lehmann, Hartmut Rehwinkel, Peter Strehike, Stefan Jaroch, Heike Schaecke, Amdt J.G. Schottelius
  • Nonsteroidal antiinflammatory agents
    Patent number: 6777409
    Abstract: The compound of formula 1 useful in the treatment of inflammation.
    Type: Grant
    Filed: July 27, 2001
    Date of Patent: August 17, 2004
    Assignee: Schering Aktiengesellschaft Patents
    Inventors: Stefan Jaroch, Manfred Lehmann, Norbert Schmees, Bernd Buchmann, Harmur Rehwinkel, Peter Droescher, Werner Skuballa, Konrad Krolikiewicz, Hartwig Hennekes, Heike Schaecke, Arndt Schottelius
  • Aminoalkyl-3, 4-dihydroquinoline derivatives as no-synthase inhibitors
    Publication number: 20040127712
    Abstract: 3,4-dihydroquinoline derivatives, a process for their production and their use in pharmaceutical agents.
    Type: Application
    Filed: October 29, 2003
    Publication date: July 1, 2004
    Inventors: Stefan Jaroch, Hartmut Rehwinkel, Peter Holscher, Detlev Sulzle, Margrit Hillmann, Gerardine Anne Burton, Fiona McDougall McDonald
  • Quinoline and isoquinoline derivatives, a process for their production and their use as inflammation inhibitors
    Publication number: 20040116694
    Abstract: The invention relates to quinoline and isoquinoline derivatives of general formula I 1
    Type: Application
    Filed: April 2, 2003
    Publication date: June 17, 2004
    Applicant: Schering AG
    Inventors: Stefan Jaroch, Manfred Lehmann, Norbert Schmees, Markus Berger, Harmut Rehwinkel, Konrad Krolikiewicz, Werner Skuballa, Heike Schaecke, Arndt J.G. Schottelius
  • Substituted quinoline CCR5 receptor antagonists
    Publication number: 20040072818
    Abstract: The present invention relates to CCR5 receptor antagonists of formulae (1a) or (1b): 1
    Type: Application
    Filed: June 26, 2003
    Publication date: April 15, 2004
    Applicant: Schering Aktiengesellschaft
    Inventors: Laura Dunning, Stefan Jaroch, Monica J. Kochanny, Wheeseong Lee, Xiongdong Lian, Meina Liang, Shou-Fu Lu, James Onuffer, Gary Phillips, Guo-Ping Wei, Bin Ye
  • Benzoxazine and benzothiazine derivatives and the use thereof in medicaments
    Publication number: 20040006075
    Abstract: Compounds of formula I, their tautomeric and isomeric forms and salts, 1
    Type: Application
    Filed: July 23, 2003
    Publication date: January 8, 2004
    Inventors: Hartmut Rehwinkel, Peter Hoelscher, Stefan Jaroch, Detley Suelzle, Margrit Hillmann, Gerardine Anne Burton, Fiona Macdougall
  • Fluorinated 3,4-dihydroquinoline derivatives used as NOS inhibitors
    Patent number: 6579883
    Abstract: The invention relates to compounds of formula (I), to a method for producing them and to their use in medicaments as NOS inhibitors.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: June 17, 2003
    Assignee: Schering Aktiengesellschaft
    Inventors: Stefan Jaroch, Hartmut Rehwinkel, Peter Hölscher, Detlev Sülzle, Margrit Hillmann, Gerardine Anne Burton, Fiona Macdougall McDonald
  • Nonsteroidal antiinflammatory agents
    Publication number: 20020077356
    Abstract: The compound of formula 1 1
    Type: Application
    Filed: July 27, 2001
    Publication date: June 20, 2002
    Inventors: Stefan Jaroch, Manfred Lehmann, Norbert Schmees, Bernd Buchmann, Harmur Rehwinkel, Peter Droescher, Werner Skuballa, Konrad Krolikiewicz, Hartwig Hennekes, Heike Schaecke, Arndr Schottelius
  • 3,4-Dihydroquinoline derivatives as nitrogen monoxide synthase (NOS) inhibitors
    Patent number: 6391887
    Abstract: The invention relates to compounds of formula (I), as defined herein. The invention also relates to the use of the inventive compounds for treatment of a disease caused by the effects of nitrogen monoxide in pathological conditions.
    Type: Grant
    Filed: August 14, 2000
    Date of Patent: May 21, 2002
    Assignee: Schering Aktiengesellschaft
    Inventors: Stefan Jaroch, Hartmut Rehwinkel, Peter Holscher, Detlev Sulzle, Margrit Hillmann, Gerardine Anne Burton, Fiona Mcdougall McDonald
  • Benzoxazine and benzothiazine derivatives and their use in pharmaceuticals
    Patent number: 6365736
    Abstract: Described are benzoxazine and benzothiazine compounds of the formula I defined herein, methods for their preparation and methods for their use in pharmaceuticals based on their activity as NO-synthases (NOS) inhibitors.
    Type: Grant
    Filed: June 15, 2000
    Date of Patent: April 2, 2002
    Assignee: Schering Aktiengesellschaft
    Inventors: Peter Hölscher, Hartmut Rehwinkel, Stefan Jaroch, Detlev Suelzle
  • Leukotriene-B4 derivatives, in particular 7-methylcyclohexyl-LTB4 antagonists
    Patent number: 6340706
    Abstract: The invention relates to leukotriene B4 derivatives of general formula (I) in which R1 stands for CH2OH, CH3, CF3, COOR4, CONR5R6; R2 stands for H or an organic acid radical with 1-15 C atoms; R3 stands for H; R4 is hydrogen, C1-C10-alkyl, C3-C10-cycloalkyl, a C6-C10-aryl radical optionally substituted by 1-3 halogen, phenyl, C1-C4-alkyl, C1-C4-alkoxy, fluoromethyl, chloromethyl, trifluoromethyl, carboxyl or hydroxy, or CH2—CO—(C6-C10) aryl, or a 5-6 link ring with at least 1 heteroatom; A is a trans-, trans-CH═CH—CH═CH, a —CH2CH2—CH═CH— or a tetramethylene group; B is a C1-C10 linear or branched-chain aklylene group or the group (a) or (b); D is a direct bonding, oxygen, sulphur, —C≡C—, —CH═CR7, or a direct bonding with B. The invention also relates to salts thereof, having physiologically compatible bases and their cyclodextrin clathrates.
    Type: Grant
    Filed: March 10, 2000
    Date of Patent: January 22, 2002
    Assignee: Schering Aktiengesellschaft
    Inventors: Bernd Buchmann, Wolfgang Frohlich, Claudia Giesen, Hartwig Hennekes, Stefan Jaroch, Werner Skuballa
  • Leukotriene B.sub.4 derivatives, in particular oximo-LTB.sub.4 - antagonists
    Patent number: 6160012
    Abstract: Leukotriene-B.sub.4 derivatives of general formula (I), in which R.sub.1 represents H, CF.sub.3, CH.sub.2 OH, and R.sub.2 represents H or an organic acid radical; R.sup.3 symbolizes H, C.sub.1 -C.sub.14 alkyl, C.sub.3 -C.sub.10 cycloalkyl, or a 5- to 6-membered aromatic heterocyclic ring with at least 1 heteroatom; R.sub.4 means hydrogen, C.sub.1 -C.sub.10 alkyl, C.sub.3 -C.sub.10 cycloalkyl; A symbolizes a trans, trans--CH.dbd.CH--CH.dbd.CH, a --CH.sub.2 CH.sub.2 --CH.dbd.CH-- or a tetramethylene group; B symbolizes a C.sub.1 -C.sub.10 -- straight-chain or branched-chain alkylene group or group (a) or (b); D can mean a direct bond, oxygen, sulfur, --C.tbd.C--, --CH.dbd.CR.sub.7, or together with B can also mean a direct bond; R.sub.5 and R.sub.6 are the same or different and represent H or C.sub.1 -C.sub.4 alkyl, or R.sub.6 represents H and R.sub.5 represents C.sub.1 -C.sub.15 alkanoyl or R.sub.8 represents SO.sub.2 ; R.sub.7 means H, C.sub.1 -C.sub.5 alkyl, chlorine, bromine; R.sub.
    Type: Grant
    Filed: March 27, 2000
    Date of Patent: December 12, 2000
    Assignee: Schering Aktiengesellschaft
    Inventors: Bernd Buchmann, Wolfgang Frohlich, Claudia Giesen, Hartwig Hennekes, Stefan Jaroch, Werner Skuballa