Abstract: Microcirculation assessment systems and methods for determining a systemic response of a patient which may be related to sepsis. A microcirculation assessment device coupled with a patient obtains a microcirculation assessment of the patient. System logic applies an algorithm to the microcirculation assessment to indirectly determine the systemic response. Artificial intelligence and/or machine learning logic collects microcirculation assessment data and corresponding actual systemic responses to define the algorithm that correlates microcirculation assessment with systemic response. System logic may recommend a therapy based the systemic response. System logic may also govern the operation of therapy equipment to deliver a therapy. The microcirculation assessment device may utilize any suitable technology to obtain the microcirculation assessment, such as ultrasound, video capillaroscopy, or thermal imaging, for example.

Abstract: A system and method for monitoring sepsis in a patient. Logic processes ultrasound image data acquired by one or more pads applied to the patient. The logic determines vascular parameters values, such as blood vessel size or shape, and the logic further determines a sepsis status and/or progression from the vascular parameter values by performing an algorithm on the vascular parameter values. The algorithm is defined utilizing artificial intelligence techniques applied to an ongoing collection data sets acquired from a plurality of sepsis monitoring systems across a plurality of patients undergoing sepsis events, where each data set includes one or more vascular parameter values and a corresponding independently acquired sepsis status for the sepsis event. The data set may also include patient data such as weight, age, etc. The pads may be wirelessly coupled with a system module. The vascular parameters may include multiple vascular sites on the patient.

Abstract: Ultraviolet light disinfection systems expose medical devices, surfaces, patients and healthcare clinicians to UV light having wavelengths consist with killing microorganisms. UV light systems may use logic to govern the operation of UV light sources so as to apply a disinfecting dose of the UV light. UV detectors measure UV light exposure. Enclosures contain medical devices and flood the medical devices with the UV light. Some enclosures accommodate a person. Some UV systems project UV light onto high-touch surfaces of a healthcare environment. Some systems may be deployed within a patient transport vehicle. Some UV systems may be incorporated into medical devices.

Abstract: A disinfecting device having a housing and an ultraviolet source located in the housing. The disinfecting device may include a tube that includes a first end connected to the housing and a second end free of the housing. An end cap may be located at the second end of the tube. In use, ultraviolet light may be emitted from the ultraviolet source and propagated to the end cap in order to disinfect a portion of a medical device.

Abstract: A system for treating infections in patients that includes an elongate probe configured for insertion into the patient body and a system module coupled with the probe. Sensors are disposed along the probe that detect infectious substances or physiological symptoms of the patient. The probe also includes light disseminating devices configured to expose the infectious substances to a light capable of disrupting the infectious substances, such as light within the ultraviolet spectrum. System logic may activate the light disseminating devices in response to sensor signals. A wireless connection enables clinician interaction with the system via external computing devices. The sensors may be disposed on external surfaces or internal luminal surfaces of the probe. The light disseminating devices may project the light away from the external surfaces or within a lumen of the probe. The light disseminating devices may include optical fibers.

Abstract: System and methods for disinfecting ultrasound probes including a disinfection module operably and physically coupled with an ultrasound-imaging system including an ultrasound probe. The disinfection module is configured to expose the external surface of the ultrasound probe to UV light to define a high-level disinfection process. Sensors determine when the ultrasound probe is disposed within a disinfecting cavity of the disinfection module and logic governs the operation of UV light sources. Logic determines a contamination level of the probe and defines an appropriate disinfection level. Exposing the probe to hydrogen peroxide is an alternative to the UV light. Logic may activate the high-level disinfection process upon placement of the probe within the cavity.

Abstract: A sterile sheath configured to enshroud a non-sterile medical device. Certain non-sterile medical equipment, e.g., consoles, computing devices, etc. are not easily sterilizable without damaging the device itself. As such, these non-sterile medical devices remain outside of the sterile field. Engaging sterile medical devices that are within the sterile field with these non-sterile medical devices can compromise the sterility of the sterile field. Disclosed herein is a sheath configured to enshroud a portion of the non-sterile medical device. Further the sheath can include an access port to allow one or more sterile medical devices to engage the non-sterile medical device disposed within the sheath.

Abstract: Connection systems and methods establish safe, routine, functional connections between sterile single patient-use (“SPU”) medical devices and multiple patient-use (“MPU”) medical devices. For example, a connection system can include a male connector associated with an SPU medical device and a female connector associated with an MTV medical device. The male connector can include a flexible member therearound but proximal of a plug of the male connector. The female connector can include a rigid member around an opening of a receptacle of the female connector. The flexible member can conform to the rigid member with a procedural barrier therebetween when the plug of the male connector is inserted into the receptacle of the female connector. Upon insertion of the plug of the male connector into the receptacle of the female connector, one or more functional connections can be established across the procedural barrier between the SPU and MPU medical devices.