Patents by Inventor Stefan K. G. Grebe
Stefan K. G. Grebe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20230204544Abstract: Provided herein are single-substance multi-point calibration techniques for quantitative mass spectrometry using the theoretical relative abundance of isotopes in a calibrator. Also provided herein are methods of determining the concentration of an analyte using a calibrator for the analyte.Type: ApplicationFiled: May 21, 2021Publication date: June 29, 2023Inventors: Stefan K.G. Grebe, Jennifer V. Kemp, Anthony D. Maus, Steven Lewis Ramsay
-
Patent number: 10712336Abstract: Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided.Type: GrantFiled: August 7, 2019Date of Patent: July 14, 2020Assignee: Mayo Foundation for Medical Education and ResearchInventors: Ravinder J. Singh, Robert L. Taylor, Stefan K. G. Grebe
-
Publication number: 20190361000Abstract: Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided.Type: ApplicationFiled: August 7, 2019Publication date: November 28, 2019Applicant: Mayo Foundation for Medical Education and ResearchInventors: Ravinder J. Singh, Robert L. Taylor, Stefan K.G. Grebe
-
Patent number: 10416149Abstract: Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided.Type: GrantFiled: September 20, 2017Date of Patent: September 17, 2019Assignee: Mayo Foundation for Medical Education and ResearchInventors: Ravinder J. Singh, Robert L. Taylor, Stefan K. G. Grebe
-
Publication number: 20180080921Abstract: Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided.Type: ApplicationFiled: September 20, 2017Publication date: March 22, 2018Applicant: Mayo Foundation for Medical Education and ResearchInventors: Ravinder J. Singh, Robert L. Taylor, Stefan K.G. Grebe
-
Patent number: 9778246Abstract: Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided.Type: GrantFiled: February 13, 2015Date of Patent: October 3, 2017Assignee: Mayo Foundation for Medical Education and ResearchInventors: Ravinder J. Singh, Robert L. Taylor, Stefan K. G. Grebe
-
Publication number: 20150153322Abstract: Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided.Type: ApplicationFiled: February 13, 2015Publication date: June 4, 2015Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCHInventors: Ravinder J. Singh, Robert L. Taylor, Stefan K.G. Grebe
-
Patent number: 8987002Abstract: Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided.Type: GrantFiled: May 3, 2013Date of Patent: March 24, 2015Assignee: Mayo Foundation for Medical Education and ResearchInventors: Ravinder J. Singh, Robert L. Taylor, Stefan K. G. Grebe
-
Patent number: 8592218Abstract: Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided.Type: GrantFiled: October 19, 2012Date of Patent: November 26, 2013Assignee: Mayo Foundation for Medical Education and ResearchInventors: Ravinder J. Singh, Robert L. Taylor, Stefan K. G. Grebe
-
Publication number: 20130244335Abstract: Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided.Type: ApplicationFiled: May 3, 2013Publication date: September 19, 2013Applicant: Mayo Foundation for Medical Education and ResearchInventors: Ravinder J. Singh, Robert L. Taylor, Stefan K.G. Grebe
-
Publication number: 20130237590Abstract: This document provides methods and materials involved in assessing thyroid neoplasms. For example, methods and materials for using microRNA (miR) levels (e.g., miR122 levels) to determine whether a thyroid neoplasm (e.g., a follicular thyroid neoplasm) is benign or malignant as well as methods and materials for using miR levels (e.g., miR122 levels) to determine whether a malignant thyroid cancer patient is likely to have a favorable or unfavorable outcome are provided. This document also provides methods and materials involved in treating cancer.Type: ApplicationFiled: July 14, 2011Publication date: September 12, 2013Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCHInventors: Norman L. Eberhardt, Bryan Mciver, Stefan K.G. Grebe, Honey V. Reddi, Alicia Algeciras-Schimnich
-
Patent number: 8349613Abstract: Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided.Type: GrantFiled: February 7, 2011Date of Patent: January 8, 2013Assignee: Mayo Foundation for Medical Education and ResearchInventors: Ravinder J. Singh, Robert L. Taylor, Stefan K. G. Grebe
-
Patent number: 7901944Abstract: Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided.Type: GrantFiled: March 26, 2010Date of Patent: March 8, 2011Assignee: Mayo Foundation for Medical Education and ResearchInventors: Ravinder J. Singh, Robert L. Taylor, Stefan K. G. Grebe
-
Publication number: 20090226925Abstract: Nucleic acids and methods for amplifying and detecting mutant BRAF sequences are provided herein. In particular, nucleic acids and methods for amplifying and detecting BRAF sequences that encode the V600E BRAF mutant are provided herein.Type: ApplicationFiled: April 15, 2009Publication date: September 10, 2009Inventors: Stefan K.G. Grebe, Mark R. Pittelkow, Kevin C. Halling, Aleksandar Sekulic, Kendall W. Cradic, Ming Mai