Patents by Inventor Stefan Kol

Stefan Kol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLYCOSYLATION OF PROTEINS
    Publication number: 20230272445
    Abstract: The present invention relates to the finding of methods to shift the glycosylation profile of recombinant produced serum glycoproteins to the predominant bi-antennary form found in human plasma. This is accomplished by providing a mammalian cell line according to the invention with a series of gene disruptions and/or gene insertions that facilitate this shift.
    Type: Application
    Filed: November 16, 2022
    Publication date: August 31, 2023
    Inventors: Bjørn Gunnar Voldborg, Stefan Kol, Anders Holmgaard Hansen, Helene Faustrup Kildegaard
  • Glycosylation of proteins
    Patent number: 11624080
    Abstract: The present invention relates to the finding of methods to shift the glycosylation profile of recombinant produced semm glycoproteins to the predominant bi-antennary form found in human plasma. This is accomplished by providing a mammalian cell line according to the invention with a series of gene disruptions and/or gene insertions that facilitate this shift.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: April 11, 2023
    Assignee: DANMARKS TEKNISKE UNIVERSITET
    Inventors: Bjørn Gunnar Voldborg, Stefan Kol, Anders Holmgaard Hansen, Helene Faustrup Kildegaard
  • NEUROTROPHIC FACTOR PROTEIN CONJUGATES AND RELATED EMBODIMENTS
    Publication number: 20220160874
    Abstract: Compositions that comprise protein conjugates comprising an NTF and a nontoxic fragment of a Clostridial neurotoxin. Vectors, host cells, and methods of use and making are also described. Pharmaceutical compositions comprising the protein conjugates described herein are used to provide neuroprotection and treat neurodegenerative diseases and neuron damage amongst other things.
    Type: Application
    Filed: April 3, 2020
    Publication date: May 26, 2022
    Applicants: TECHNICAL UNIVERSITY OF DENMARK, SIRA PHARMACEUTICALS INC.
    Inventors: Bjørn VOLDBORG, Stefan KOL, Johnny ARNSDORF, Shaji JOSEPH, Elizabeth BRUNK
  • GLYCOSYLATION OF PROTEINS
    Publication number: 20210262000
    Abstract: The present invention relates to the finding of methods to shift the glycosylation profile of recombinant produced semm glycoproteins to the predominant bi-antennary form found in human plasma. This is accomplished by providing a mammalian cell line according to the invention with a series of gene disruptions and/or gene insertions that facilitate this shift.
    Type: Application
    Filed: November 16, 2018
    Publication date: August 26, 2021
    Inventors: Bjørn Gunnar Voldborg, Stefan Kol, Anders Holmgaard Hansen, Helene Faustrup Kildegaard