Patents by Inventor Stefan Laufer

Stefan Laufer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fused pyrrole compounds, pharmaceutical agents containing the same, and the use thereof
    Publication number: 20040122002
    Abstract: The present invention relates to fused pyrrole compounds of the formula 1.
    Type: Application
    Filed: September 27, 2002
    Publication date: June 24, 2004
    Inventors: Hans Guenter Striegel, Stefan Laufer, Karola Tollmann, Susanne Tries
  • 2-thio-substituted imidazole derivatives and the use thereof in the pharmaceutical industry
    Publication number: 20040116416
    Abstract: The invention relates to 2-thio-substituted imidazole derivatives of the formula I 1
    Type: Application
    Filed: January 28, 2004
    Publication date: June 17, 2004
    Inventors: Stefan Laufer, Dunja Kotschenreuther, Philipp Merckle, Karola Tollmann, Hans-Gunter Striegel
  • 4-Pyridyl-and 2,4-pyrimidinyl-substituted pyrrole derivatives and their use in pharmacy
    Publication number: 20030153558
    Abstract: The present invention relates to 4-pyridyl- und 2,4-pyrimidinyl-substituted pyrrole derivatives and their use in pharmacy, of the formula 1 1
    Type: Application
    Filed: November 5, 2002
    Publication date: August 14, 2003
    Inventors: Hans-Guenter Striegel, Stefan Laufer, Karola Tollmann, Susanne Tries
  • 2-arylalkylthio -imidazoles, 2-arylalkenyl -thio -imidazoles and 2-arylalkinyl -thio -imidazoles as anti -inflammatory substances and substances inhibiting the release of cytokine
    Patent number: 6432988
    Abstract: The invention relates to 4-heteroaryl-5-phenylimidazole derivatives having 2-arylalkylthio, 2-arylalkenylthio and 2-arylalkynylthio substitution, of the general formula I: in which Ar is a phenyl radical, Het is a hetero aromatic radical, A is an alkylene chain, R1 is an alkylthio, alkylsulfinyl, alkylsulfonyl, sulfonamido or alkylcarbonyl group and R2 is an alkyl, hydroxyl, alkoxy, alkoxycarbonyl, sulfonamido, carboxyl, nitro or aminocarbonyl group or a halogen atom. n can be 1 or 2 and m is 0 to 2. The compounds according to the invention show antiinflammatory activity.
    Type: Grant
    Filed: May 11, 2001
    Date of Patent: August 13, 2002
    Assignee: Merckle GmbH
    Inventors: Stefan Laufer, Hans-Günter Striegel, Karola Neher
  • Process for preparing 6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl-acetic acid
    Patent number: 6417371
    Abstract: The present invention relates to a process process for the preparation of the compound of the formula I where the compound of the formula III is reacted with oxalyl chloride and the product obtained is treated with hydrazine and an alkali metal hydroxide in the aqueous phase at elevated temperature, after treatment is complete a three-phase system is produced by addition of an ether and the compound of the formula I is obtained by acidifying the middle phase. The invention moreover relates to a polymorph of the compound of the formula I.
    Type: Grant
    Filed: January 26, 2001
    Date of Patent: July 9, 2002
    Assignee: Merckle GmbH
    Inventors: Thomas Kammermeier, Stefan Laufer, Philipp Merckle, Hans-Guenter Striegel
  • Process for preparing 6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl-acetic acid
    Publication number: 20020028953
    Abstract: The present invention relates to a process process for the preparation of the compound of the formula I 1
    Type: Application
    Filed: January 26, 2001
    Publication date: March 7, 2002
    Applicant: Merckle GmbH
    Inventors: Thomas Kammermeier, Stefan Laufer, Philipp Merckle, Hans-Guenter Striegel
  • ?A!-anellated pyrrole derivatives and their use in pharmacology
    Patent number: 5958943
    Abstract: The present invention relates to heterocyclic compounds of the formula ##STR1## in which R.sup.1 -R.sup.7, B, a and X have the meanings recited in the specification. These compounds are usable in the treatment of diseases of the rheumatoid variety and for the prevention of allergically induced diseases.
    Type: Grant
    Filed: March 28, 1996
    Date of Patent: September 28, 1999
    Assignee: Merckle GmbH
    Inventors: Stefan Laufer, Hans Gunther Striegel, Gerd Dannhardt
  • ?a!-Annelated pyrrole derivatives and pharmaceutical use thereof
    Patent number: 5942535
    Abstract: The present invention relates to heterocyclic compounds of the formula ##STR1## in which R.sup.1 -R.sup.7, B, a and X have the meanings recited in the specification. These compounds are usable in the treatment of diseases of the rheumatoid group and for the prevention of allergically induced diseases.
    Type: Grant
    Filed: March 28, 1997
    Date of Patent: August 24, 1999
    Assignee: Merckle GmbH
    Inventors: Stefan Laufer, Hans Gunther Striegel, Gerd Dannhardt
  • ?A!-annellated pyrrole derivatives and their use in pharmacology
    Patent number: 5939415
    Abstract: The present invention relates to heterocyclic compounds with the formula ##STR1## in which R.sup.1 to R.sup.7, B, a, and X have the meanings indicated in the specification. These compounds can be used for the treatment of diseases of the rheumatic variety and for the prevention of allergically-induced diseases.
    Type: Grant
    Filed: March 28, 1997
    Date of Patent: August 17, 1999
    Assignee: Merckle GmbH
    Inventors: Stefan Laufer, Hans Gunther Striegel, Gerd Dannhardt