Patents by Inventor Stefan M. C. Pype

Stefan M. C. Pype has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CD40-interacting and TRAF-interacting proteins
    Patent number: 7098322
    Abstract: The present invention relates to novel proteins interacting with the cytoplasmic domain of CD40, which are useful in the treatment of CD40 and/or NF-?B related diseases. Surprisingly, these proteins do not show significant amino acid sequence identity with the members of tumor necrosis factor receptor associated factor (TRAF) family; and thus, offer the possibility to modulate the CD40 and/or NF-?B signaling pathway independently from interaction of TRAF with CD40.
    Type: Grant
    Filed: January 15, 2004
    Date of Patent: August 29, 2006
    Assignee: Vlaams Interuniversitair Instituut voor Biotechnologie VZW
    Inventors: Stefan M. C. Pype, Jacques E. F. Remacle, Danny F. E. Huylebroeck
  • CD40-Interacting and TRAF-interacting proteins
    Patent number: 6812203
    Abstract: The present invention relates to novel proteins interacting with the cytoplasmic domain of CD40, which are useful in the treatment of CD40 and/or NF-kB related diseases. Surprisingly, these proteins do not show significant homology with the TRAF-protein family and therefore offer the possibility to modulate the CD40 and/or NF-kB pathway independently from the TRAF-CD40 interaction.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: November 2, 2004
    Assignee: Vlaams Interuniversitair Instituut voor Biotechnologie VZW
    Inventors: Stefan M. C. Pype, Jacques E. F. Remacle, Danny F. E. Huylebroeck