Patents by Inventor Stefan Margraf

Stefan Margraf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11185827
    Abstract: A surface-modified filter membrane for filtering blood, in particular for separating blood plasma and blood serum, and a method for the production thereof, a filter provided therewith and the use thereof.
    Type: Grant
    Filed: July 16, 2018
    Date of Patent: November 30, 2021
    Assignee: BOEHRINGER INGELHEIM VETMEDICA GMBH
    Inventors: Christoph Weber, Heinz Schoeder, Jens Altrichter, Roland Kirchner, Stefan Margraf, Michael Scholl
  • Patent number: 10406271
    Abstract: The present invention relates to a method for filtering blood to produce plasma or serum and to a blood filter for the production of plasma or serum from a blood sample. The invention further relates to a kit comprising a blood filter for the production of plasma or serum from a blood sample and a syringe.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: September 10, 2019
    Assignee: Leukocare AG
    Inventors: Stefan Margraf, Martin Scholz
  • Publication number: 20190046715
    Abstract: The present invention relates to a method for filtering blood to produce plasma or serum and to a blood filter for the production of plasma or serum from a blood sample. The invention further relates to a kit comprising a blood filter for the production of plasma or serum from a blood sample and a syringe.
    Type: Application
    Filed: October 15, 2018
    Publication date: February 14, 2019
    Inventors: Stefan Margraf, Martin Scholz
  • Publication number: 20190015790
    Abstract: A surface-modified filter membrane for filtering blood, in particular for separating blood plasma and blood serum, and a method for the production thereof, a filter provided therewith and the use thereof.
    Type: Application
    Filed: July 16, 2018
    Publication date: January 17, 2019
    Applicant: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Christoph Weber, Heinz Ulrich Gerhard Schoeder, Jens Altrichter, Roland Kirchner, Stefan Margraf, Michael Scholl
  • Publication number: 20180318471
    Abstract: The invention relates to means and methods for the disinfection of an insertion channel to prevent in particular catheter sepsis, which significantly reduces the carry-over of germs even out of deeper skin layers by means of medical instruments, such as catheters, to be introduced into non-natural openings and also permits the decontamination of perioperatively contaminated medical instruments. The disinfection of the insertion channel is achieved by means of a method for the perioperative coating of a medical instrument to be inserted into an invasively produced opening before use, comprising the application of a viscous or foam-like composition containing at least one anti-infective compound, preferably a gel having octenidine, by means of an applicator, such that when said gel is used, the composition is also specifically effective in the first millimeters of the insertion channel. Furthermore, an immediate disinfecting action is provided over the entire coated surface.
    Type: Application
    Filed: July 13, 2018
    Publication date: November 8, 2018
    Applicant: Solvamed GmbH
    Inventors: Stefan Margraf, Jan Stange
  • Patent number: 10052414
    Abstract: The invention relates to means and methods for the disinfection of an insertion channel to prevent in particular catheter sepsis, which significantly reduces the carry-over of germs even out of deeper skin layers by means of medical instruments, such as catheters, to be introduced into non-natural openings and also permits the decontamination of perioperatively contaminated medical instruments. The disinfection of the insertion channel is achieved by means of a method for the perioperative coating of a medical instrument to be inserted into an invasively produced bodily opening before use, comprising the application of a preferably viscous or foam-like composition containing at least one anti-infective compound, preferably a gel having octenidine, by means of an applicator, such that when said gel is used, the composition is also specifically effective in the first millimeters of the insertion channel. Furthermore, an immediate disinfecting action is provided over the entire coated surface.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: August 21, 2018
    Assignee: Solvamed GmbH
    Inventors: Stefan Margraf, Jan Stange
  • Publication number: 20180204137
    Abstract: The present invention relates to the use of a composition comprising (a) at least three different amino acids, (b) at least two different amino acids and a saponin or (c) at least one dipeptide or tripeptide for stabilizing biomolecules immobilized on a solid carrier. The invention furthermore relates to a method for producing stabilized biomolecules, comprising embedding the biomolecules in the compositions according to the invention and a method of producing a solid carrier having biomolecules attached thereto. The invention furthermore relates to a solid carrier producible or produced by the method of the invention and a method of diagnosing a disease using the carrier of the invention.
    Type: Application
    Filed: October 18, 2017
    Publication date: July 19, 2018
    Inventors: Stefan Margraf, Anja Breuer, Martin Scholz, Jens Altrichter
  • Patent number: 9926383
    Abstract: The present invention relates to a method of producing a solid coated carrier carrying biological material. Furthermore, the invention relates to a solid coated carrier to which biological material is attached and uses of the solid coated carrier for the preparation of a medical product. Moreover, the invention provides a method for the contacting, filtration or cleaning of blood, lymph or liquor cerebrospinalis of a patient, a method for the diagnosis of a disease and a diagnostic composition.
    Type: Grant
    Filed: May 7, 2007
    Date of Patent: March 27, 2018
    Assignee: LEUKOCARE AG
    Inventors: Stefan Margraf, Martin Scholz
  • Patent number: 9797895
    Abstract: The present invention relates to the use of a composition comprising (a) at least three different amino acids, (b) at least two different amino acids and a saponin or (c) at least one dipeptide or tripeptide for stabilizing biomolecules immobilized on a solid carrier. The invention furthermore relates to a method for producing stabilized biomolecules, comprising embedding the biomolecules in the composition according to the invention and a method of producing a solid carrier having biomolecules attached thereto. The invention furthermore relates to a solid carrier producible or produced by the method of the invention and a method of diagnosing a disease using the carrier of the invention.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: October 24, 2017
    Assignee: Leukocare AG
    Inventors: Stefan Margraf, Anja Breuer, Martin Scholz, Jens Altrichter
  • Publication number: 20160082174
    Abstract: The present invention relates to a method for filtering blood to produce plasma or serum and to a blood filter for the production of plasma or serum from a blood sample. The invention further relates to a kit comprising a blood filter for the production of plasma or serum from a blood sample and a syringe.
    Type: Application
    Filed: December 9, 2015
    Publication date: March 24, 2016
    Inventors: Stefan Margraf, Martin Scholz
  • Publication number: 20140370067
    Abstract: The invention relates to means and methods for the disinfection of an insertion channel to prevent in particular catheter sepsis, which significantly reduces the carry-over of germs even out of deeper skin layers by means of medical instruments, such as catheters, to be introduced into non-natural openings and also permits the decontamination of perioperatively contaminated medical instruments. The disinfection of the insertion channel is achieved by means of a method for the perioperative coating of a medical instrument to be inserted into an invasively produced bodily opening before use, comprising the application of a preferably viscous or foam-like composition containing at least one anti-infective compound, preferably a gel having octenidine, by means of an applicator, such that when said gel is used, the composition is also specifically effective in the first millimeters of the insertion channel. Furthermore, an immediate disinfecting action is provided over the entire coated surface.
    Type: Application
    Filed: January 22, 2013
    Publication date: December 18, 2014
    Inventors: Stefan Margraf, Jan Stange
  • Publication number: 20120118825
    Abstract: The present invention relates to a method for filtering blood to produce plasma or serum and to a blood filter for the production of plasma or serum from a blood sample. The invention further relates to a kit comprising a blood filter for the production of plasma or serum from a blood sample and a syringe.
    Type: Application
    Filed: June 17, 2010
    Publication date: May 17, 2012
    Applicant: Leukocare AG
    Inventors: Stefan Margraf, Martin Scholz
  • Publication number: 20120107829
    Abstract: The present invention relates to the use of a composition comprising (a) at least three different amino acids, (b) at least two different amino acids and a saponin or (c) at least one dipeptide or tripeptide for stabilizing biomolecules immobilized on a solid carrier. The invention furthermore relates to a method for producing stabilized biomolecules, comprising embedding the biomolecules in the composition according to the invention and a method of producing a solid carrier having biomolecules attached thereto. The invention furthermore relates to a solid carrier producible or produced by the method of the invention and a method of diagnosing a disease using the carrier of the invention.
    Type: Application
    Filed: March 31, 2010
    Publication date: May 3, 2012
    Applicant: LEUKOCARE AG
    Inventors: Stefan Margraf, Anja Breuer, Martin Scholz, Jens Altrichter
  • Publication number: 20100291665
    Abstract: The present invention relates to a method of producing a solid coated carrier carrying biological material. Furthermore, the invention relates to a solid coated carrier to which biological material is attached and uses of the solid coated carrier for the preparation of a medical product. Moreover, the invention provides a method for the contacting, filtration or cleaning of blood, lymph or liquor cerebrospinalis of a patient, a method for the diagnosis of a disease and a diagnostic composition.
    Type: Application
    Filed: November 7, 2008
    Publication date: November 18, 2010
    Applicant: LEUKOCARE AG
    Inventors: Stefan Margraf, Martin Scholz, Jens Altrichter
  • Publication number: 20100261223
    Abstract: A device and a method for detecting components in blood, in particular for determining the concentration of components in blood or water is provided. Moreover, a use of a device and/or a method for determining components in blood is provided and a kit including the device and a fluorescence standard.
    Type: Application
    Filed: October 31, 2008
    Publication date: October 14, 2010
    Inventors: Stefan Margraf, Martin Scholz
  • Publication number: 20090298078
    Abstract: The present invention relates to a method for the detection of an activation of the immune system, preferably in the sense of an NET formation, or the extent of cell death in a non-tumorous tissue or in a body fluid, wherein free DNA is measured in a sample from an individual. Furthermore, the invention relates to a method for the production of a kit for the detection of an activation of the immune system or the extent of cell death in an individual, comprising the packaging of a fluorescent dye and a DNA standard in at least one container.
    Type: Application
    Filed: October 1, 2007
    Publication date: December 3, 2009
    Applicant: Leukocare AG
    Inventor: Stefan Margraf
  • Publication number: 20090269778
    Abstract: The present invention relates to a method of producing a solid coated carrier carrying biological material. Furthermore, the invention relates to a solid coated carrier to which biological material is attached and uses of the solid coated carrier for the preparation of a medical product. Moreover, the invention provides a method for the contacting, filtration or cleaning of blood, lymph or liquor cerebrospinalis of a patient, a method for the diagnosis of a disease and a diagnostic composition.
    Type: Application
    Filed: May 7, 2007
    Publication date: October 29, 2009
    Applicant: LEUKOCARE AG
    Inventors: Stefan Margraf, Martin Scholz