Patents by Inventor Stefan Meuer

Stefan Meuer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SKAP55 compositions and methods of use therefor
    Patent number: 5942415
    Abstract: Isolated nucleic acid molecules encoding a novel protein, SKAP55, that interacts with the protein tyrosine kinase Fyn, are disclosed. SKAP55 protein has an apparent native molecular weight of 55 kDa, an isoelectric point of 4.3 and contains a pleckstrin homology (PH) domain and a src homology 3 (SH3) domain. In addition to isolated nucleic acids molecules encoding SKAP55 protein, the invention provides antisense nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals carrying a SKAP55 transgene. The invention further provides isolated SKAP55 proteins and peptides, SKAP55 fusion proteins and anti-SKAP55 antibodies.
    Type: Grant
    Filed: September 13, 1996
    Date of Patent: August 24, 1999
    Inventors: Burkhart Schraven, Anne Marie-Cardine, Stefan Meuer, Henning Kirchgessner
  • Nucleic acid molecules encoding PP32: a newly identified CD45-associated protein
    Patent number: 5846822
    Abstract: This invention relates to a newly identified protein useful for treating diseases of the immune system, methods for obtaining said protein, isolated nucleic acids encoding said protein, and methods for obtaining inhibitors of said protein. The protein of this invention is characterized by an apparent molecular weight of about 32 kD, an isoelectric point of about 4.0-4.5 and coprecipitation with CD45. The protein may also be used in in vitro or in vivo assays to identify inhibitors of T cell activation.
    Type: Grant
    Filed: April 22, 1996
    Date of Patent: December 8, 1998
    Assignee: BASF Aktiengesselschaft
    Inventors: Stefan Meuer, Burkhart Schraven, David Schoenhaut, Sheldon Ratnofsky
  • Bispecific molecules recognizing lymphocyte antigen CD2 and tumor antigens
    Patent number: 5798229
    Abstract: The present invention relates to novel and highly effective bispecific antibody fragments which recognize lymphocyte CD2 antigen and any variable tumor antigen. Moreover, the invention relates to two new monoclonal antibodies terms AICD2.M1 and AICD2.M2. A combination of these antibodies, whereby at least one of them is a bispecific antibody fragment, can be used successfully in tumor therapy and diagnostics.
    Type: Grant
    Filed: August 2, 1994
    Date of Patent: August 25, 1998
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Wolfgang Strittmatter, Carlota-Silvia Jaggle, Stefan Meuer, Burkhart Shraven, Martin Wild
  • pp: A newly identified CD45-associated protein
    Patent number: 5510461
    Abstract: This invention relates to a newly identified protein useful for treating diseases of the immune system, methods for obtaining said protein, isolated nucleic acids encoding said protein, and methods for obtaining inhibitors of said protein. The protein of this invention is characterized by an apparent molecular weight of about 32 kD, an isoelectric point of about 4.0-4.5 and coprecipitation with CD45. The protein may also be used in in vitro or in vivo assays to identify inhibitors of T cell activation.
    Type: Grant
    Filed: February 14, 1994
    Date of Patent: April 23, 1996
    Assignee: BASF Aktiengesellschaft
    Inventors: Stefan Meuer, Burkhart Schraven, David Schoenhaut, Sheldon Ratnofsky