Patents by Inventor Stefan MIX

Stefan MIX has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SQUALENE HOPENE CYCLASE DERIVATIVES AND USE THEREOF FOR PRODUCING AMBROX
    Publication number: 20230265474
    Abstract: Variants of Squalene Hopene Cyclase (SHC) isolated from Gluconobacter morbifer are provided as is a method for using the variant G. morbifer SHC to biocatalytically convert homofarnesol to ambrox.
    Type: Application
    Filed: September 2, 2021
    Publication date: August 24, 2023
    Inventors: Lyndsey Jane Bannon, Daniel Fernando Andrade Ribeiro Dourado, David Andrew Lipscomb, Peter Brian Alexander McIntyre, Stefan Mix, Thomas Shaw Shaw Moody, Derek Quinn, Paul Daniel Jones, Anubhav P.S. Narula
  • PROCESS FOR PRODUCING 4,5-DIHYDRO-1H-PYRAZOLES AND INTERMEDIATES
    Publication number: 20230159464
    Abstract: Described are processes for the manufacture of compounds containing a (S)-4,5-dihydro-1H-pyrazole ring. These processes include a chiral resolution step of an intermediate using selected chiral resolving agents. For example, the chiral resolving agents may be selected from (?)-quinine, (R)-phenethylamine, (S)-phenethylamine, (S)-1-naphthylethy lamine, (R)-(?)-2-amino-3-methyl-1-butanol, (?)-cinchonidine, (?)-spartein, (R)-1-naphthylethy lamine, D-arginine, L-lysine, (S)-(+)-2-pyrrolidinemethanol and(1R,2S)-(+)-cis-1-amino-2-indanol.
    Type: Application
    Filed: April 7, 2021
    Publication date: May 25, 2023
    Inventors: JEREMY GREEN, Stefan MIX, Vincent Brunet, Gareth Brown, Drazen Pavlovic
  • ENZYMATIC PROCESS FOR THE PREPARATION OF (1S,2R)-2-(DIFLUOROMETHYL)-1-(PROPOXYCARBONYL)CYCLOPROPANECARBOXYLIC ACID
    Publication number: 20200024621
    Abstract: Disclosed are methods of synthesizing enantioenriched difluoroalkylcyclopropyl amino esters and their salts, such as the dicyclohexylamine salt of (1S,2R)-2-(difluoromethyl)-1-(propoxycarbonyl)cyclopropane carboxylic acid. These compounds are useful intermediates in the synthesis of viral protease inhibitors.
    Type: Application
    Filed: June 7, 2019
    Publication date: January 23, 2020
    Inventors: Michael J. Abrahamson, Angelica B. Kielbus, William T. Riordan, David R. Hill, Sanjay R. Chemburkar, Rajarathnam E. Reddy, Timothy B. Towne, Jianzhang Mei, Stefan Mix, Gareth J. Brown
  • Enzymatic process for the preparation of (1S,2R)-2-(difluoromethyl)-1-(propoxycarbonyl)cyclopropanecarboxylic acid
    Patent number: 10316338
    Abstract: Disclosed are methods of synthesizing enantioenriched difluoroalkylcyclopropyl amino esters and their salts, such as the dicyclohexylamine salt of (1S,2R)-2-(difluoromethyl)-1-(propoxycarbonyl)cyclopropane carboxylic acid. These compounds are useful intermediates in the synthesis of viral protease inhibitors.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: June 11, 2019
    Assignee: Abb Vie Inc.
    Inventors: Michael J. Abrahamson, Angelica B. Kielbus, William T. Riordan, David R. Hill, Sanjay R. Chemburkar, Rajarathnam E. Reddy, Timothy B. Towne, Jianzhang Mei, Gareth J. Brown, Stefan Mix
  • Method of preparing AZA-pyridone compounds
    Patent number: 10183945
    Abstract: Disclosed herein are methods for obtaining aza-pyridone compounds, which can be useful for ameliorating and/or treating a disease and/or a condition, including an orthomyxovirus infection.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: January 22, 2019
    Assignee: ALIOS BIOPHARMA, INC.
    Inventors: Michael Hunter Welch, Leonid Beigelman, Robert Than Hendricks, Andras Horvath, Gareth Brown, Prasad Ganji, Stefan Mix
  • METHOD OF PREPARING AZA-PYRIDONE COMPOUNDS
    Publication number: 20170260189
    Abstract: Disclosed herein are methods for obtaining aza-pyridone compounds, which can be useful for ameliorating and/or treating a disease and/or a condition, including an orthomyxovirus infection.
    Type: Application
    Filed: March 10, 2017
    Publication date: September 14, 2017
    Inventors: Michael Hunter WELCH, Leonid BEIGELMAN, Robert Than HENDRICKS, Andras HORVATH, Gareth BROWN, Prasad GANJI, Stefan MIX